88305 covers routine surgical pathology examination of a specimen. 88355 applies when quantitative morphometric analysis of skeletal muscle is also performed.
On this page
CMS RVU26D · Effective 2026-10-01
88355 in Austin
Office / nonfacility
$144.88
Base rate per service
Facility setting
Not available in this setting
Base rate per service
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
Surgical pathology
About 88355: Skeletal muscle morphometric analysis
Reports quantitative morphometric measurement of skeletal muscle biopsy tissue, typically when evaluating suspected myopathic or neurogenic disease beyond routine histologic examination.
A pathology laboratory performs quantitative morphometric assessment of skeletal muscle tissue, commonly from a biopsy obtained during evaluation of suspected myopathy, muscular dystrophy, or neurogenic muscle change. The analysis measures histologic muscle-fiber features; a pathologist interprets the findings in the context of the tissue and clinical question. It may be performed in a hospital laboratory or an independent pathology laboratory.
Report 88355 when skeletal muscle morphometric analysis is performed in addition to routine tissue examination, not for routine microscopic review alone. The report should identify the specimen and document the quantitative analysis and findings. CMS recognizes a professional component for interpretation and a technical component for the equipment and staff performing the test. Report modifier 26 for the professional component, modifier TC for the technical component, or neither modifier for the global service.
CMS billing rules for 88355
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU1.80 · 43%
- Practice expense (office) RVU2.37 · 56%
- Malpractice RVU0.03 · 1%
139
Medicare services in 2024 · #4614 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
88355 compared with similar codes
Office rates for Austin, from the same CMS release.
The same code, a different location
How does Austin compare?
In Beaumont, the office rate for 88355 is $133.09—$11.79 lower than the $144.88 rate in Austin. Both use the same code, release and participation basis.
88355 across payment areas
Same release and payment basis · bars start at $0
Austin · This locality
$144.88
$133.09
$11.79 lower than Austin
$139.83
$5.05 lower than Austin
$140.37
$4.51 lower than Austin
$139.59
$5.29 lower than Austin
$140.04
$4.84 lower than Austin
$140.59
$4.29 lower than Austin
Other payment areas listed in Texas appear first, followed by selected cross-country examples. The chart compares amounts, not distance.
Across 109 of 109 CMS payment localities with a supported office rate, 88355 ranges from $128.64 in Arkansas to $181.42 in San Jose-Sunnyvale-Santa Clara (San Benito Cnty). This is a geographic range, not an average.
The code’s RVUs stay the same in these comparisons. Geographic adjustments to work, practice expense and malpractice change the dollar amount. A city name alone may not identify the payment area for a service address.
Compare all 108 other payment areas
Rest Of Texas
Texas · 88355
Office
$136.15
Facility
Unavailable
$8.73 lower than Austin for the office setting.
Los Angeles-Long Beach-Anaheim (Los Angeles/Orange Cnty)
California · 88355
Office
$156.90
Facility
Unavailable
$12.02 higher than Austin for the office setting.
Dc + Md/Va Suburbs
District of Columbia · 88355
Office
$157.73
Facility
Unavailable
$12.85 higher than Austin for the office setting.
Miami
Florida · 88355
Office
$145.06
Facility
Unavailable
$0.18 higher than Austin for the office setting.
Chicago
Illinois · 88355
Office
$142.40
Facility
Unavailable
$2.48 lower than Austin for the office setting.
Manhattan
New York · 88355
Office
$157.54
Facility
Unavailable
$12.66 higher than Austin for the office setting.
Alaska*
Alaska · 88355
Office
$175.04
Facility
Unavailable
$30.16 higher than Austin for the office setting.
Alabama
Alabama · 88355
Office
$129.95
Facility
Unavailable
$14.93 lower than Austin for the office setting.
Arkansas
Arkansas · 88355
Office
$128.64
Facility
Unavailable
$16.24 lower than Austin for the office setting.
Arizona
Arizona · 88355
Office
$137.69
Facility
Unavailable
$7.19 lower than Austin for the office setting.
Bakersfield
California · 88355
Office
$148.63
Facility
Unavailable
$3.75 higher than Austin for the office setting.
Chico
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
El Centro
California · 88355
Office
$148.45
Facility
Unavailable
$3.57 higher than Austin for the office setting.
Fresno
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Hanford-Corcoran
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Madera
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Merced
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Modesto
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Napa
California · 88355
Office
$168.75
Facility
Unavailable
$23.87 higher than Austin for the office setting.
Oxnard-Thousand Oaks-Ventura
California · 88355
Office
$156.00
Facility
Unavailable
$11.12 higher than Austin for the office setting.
Redding
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Rest Of California
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Riverside-San Bernardino-Ontario
California · 88355
Office
$148.82
Facility
Unavailable
$3.94 higher than Austin for the office setting.
Sacramento-Roseville-Folsom
California · 88355
Office
$154.89
Facility
Unavailable
$10.01 higher than Austin for the office setting.
Salinas
California · 88355
Office
$154.27
Facility
Unavailable
$9.39 higher than Austin for the office setting.
San Diego-Chula Vista-Carlsbad
California · 88355
Office
$157.14
Facility
Unavailable
$12.26 higher than Austin for the office setting.
San Francisco-Oakland-Berkeley (Marin Cnty)
California · 88355
Office
$177.91
Facility
Unavailable
$33.03 higher than Austin for the office setting.
San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty)
California · 88355
Office
$177.87
Facility
Unavailable
$32.99 higher than Austin for the office setting.
San Jose-Sunnyvale-Santa Clara (San Benito Cnty)
California · 88355
Office
$181.42
Facility
Unavailable
$36.54 higher than Austin for the office setting.
San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty)
California · 88355
Office
$181.28
Facility
Unavailable
$36.40 higher than Austin for the office setting.
San Luis Obispo-Paso Robles
California · 88355
Office
$151.84
Facility
Unavailable
$6.96 higher than Austin for the office setting.
Santa Cruz-Watsonville
California · 88355
Office
$158.10
Facility
Unavailable
$13.22 higher than Austin for the office setting.
Santa Maria-Santa Barbara
California · 88355
Office
$154.64
Facility
Unavailable
$9.76 higher than Austin for the office setting.
Santa Rosa-Petaluma
California · 88355
Office
$159.67
Facility
Unavailable
$14.79 higher than Austin for the office setting.
Stockton
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Vallejo
California · 88355
Office
$168.70
Facility
Unavailable
$23.82 higher than Austin for the office setting.
Visalia
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Yuba City
California · 88355
Office
$148.44
Facility
Unavailable
$3.56 higher than Austin for the office setting.
Colorado
Colorado · 88355
Office
$145.85
Facility
Unavailable
$0.97 higher than Austin for the office setting.
Connecticut
Connecticut · 88355
Office
$147.79
Facility
Unavailable
$2.91 higher than Austin for the office setting.
Delaware
Delaware · 88355
Office
$139.53
Facility
Unavailable
$5.35 lower than Austin for the office setting.
Fort Lauderdale
Florida · 88355
Office
$142.12
Facility
Unavailable
$2.76 lower than Austin for the office setting.
Rest Of Florida
Florida · 88355
Office
$137.30
Facility
Unavailable
$7.58 lower than Austin for the office setting.
Atlanta
Georgia · 88355
Office
$141.93
Facility
Unavailable
$2.95 lower than Austin for the office setting.
Rest Of Georgia
Georgia · 88355
Office
$131.93
Facility
Unavailable
$12.95 lower than Austin for the office setting.
Hawaii, Guam
Hawaii · 88355
Office
$150.71
Facility
Unavailable
$5.83 higher than Austin for the office setting.
Iowa
Iowa · 88355
Office
$132.95
Facility
Unavailable
$11.93 lower than Austin for the office setting.
Idaho
Idaho · 88355
Office
$133.42
Facility
Unavailable
$11.46 lower than Austin for the office setting.
East St. Louis
Illinois · 88355
Office
$134.97
Facility
Unavailable
$9.91 lower than Austin for the office setting.
Rest Of Illinois
Illinois · 88355
Office
$133.96
Facility
Unavailable
$10.92 lower than Austin for the office setting.
Suburban Chicago
Illinois · 88355
Office
$143.62
Facility
Unavailable
$1.26 lower than Austin for the office setting.
Indiana
Indiana · 88355
Office
$133.99
Facility
Unavailable
$10.89 lower than Austin for the office setting.
Kansas
Kansas · 88355
Office
$132.19
Facility
Unavailable
$12.69 lower than Austin for the office setting.
Kentucky
Kentucky · 88355
Office
$131.41
Facility
Unavailable
$13.47 lower than Austin for the office setting.
New Orleans
Louisiana · 88355
Office
$135.75
Facility
Unavailable
$9.13 lower than Austin for the office setting.
Rest Of Louisiana
Louisiana · 88355
Office
$131.14
Facility
Unavailable
$13.74 lower than Austin for the office setting.
Metropolitan Boston
Massachusetts · 88355
Office
$158.00
Facility
Unavailable
$13.12 higher than Austin for the office setting.
Rest Of Massachusetts
Massachusetts · 88355
Office
$145.24
Facility
Unavailable
$0.36 higher than Austin for the office setting.
Baltimore/Surr. Cntys
Maryland · 88355
Office
$147.26
Facility
Unavailable
$2.38 higher than Austin for the office setting.
Rest Of Maryland
Maryland · 88355
Office
$141.75
Facility
Unavailable
$3.13 lower than Austin for the office setting.
Rest Of Maine
Maine · 88355
Office
$133.57
Facility
Unavailable
$11.31 lower than Austin for the office setting.
Southern Maine
Maine · 88355
Office
$139.20
Facility
Unavailable
$5.68 lower than Austin for the office setting.
Detroit
Michigan · 88355
Office
$138.20
Facility
Unavailable
$6.68 lower than Austin for the office setting.
Rest Of Michigan
Michigan · 88355
Office
$133.53
Facility
Unavailable
$11.35 lower than Austin for the office setting.
Minnesota
Minnesota · 88355
Office
$141.87
Facility
Unavailable
$3.01 lower than Austin for the office setting.
Metropolitan Kansas City
Missouri · 88355
Office
$135.43
Facility
Unavailable
$9.45 lower than Austin for the office setting.
Metropolitan St. Louis
Missouri · 88355
Office
$136.49
Facility
Unavailable
$8.39 lower than Austin for the office setting.
Rest Of Missouri
Missouri · 88355
Office
$129.33
Facility
Unavailable
$15.55 lower than Austin for the office setting.
Mississippi
Mississippi · 88355
Office
$129.02
Facility
Unavailable
$15.86 lower than Austin for the office setting.
Montana**
Montana · 88355
Office
$140.28
Facility
Unavailable
$4.60 lower than Austin for the office setting.
North Carolina
North Carolina · 88355
Office
$134.62
Facility
Unavailable
$10.26 lower than Austin for the office setting.
North Dakota**
North Dakota · 88355
Office
$139.69
Facility
Unavailable
$5.19 lower than Austin for the office setting.
Nebraska
Nebraska · 88355
Office
$133.57
Facility
Unavailable
$11.31 lower than Austin for the office setting.
New Hampshire
New Hampshire · 88355
Office
$143.40
Facility
Unavailable
$1.48 lower than Austin for the office setting.
Northern Nj
New Jersey · 88355
Office
$156.81
Facility
Unavailable
$11.93 higher than Austin for the office setting.
Rest Of New Jersey
New Jersey · 88355
Office
$150.07
Facility
Unavailable
$5.19 higher than Austin for the office setting.
New Mexico
New Mexico · 88355
Office
$133.91
Facility
Unavailable
$10.97 lower than Austin for the office setting.
Nevada**
Nevada · 88355
Office
$140.20
Facility
Unavailable
$4.68 lower than Austin for the office setting.
Nyc Suburbs/Long Island
New York · 88355
Office
$159.95
Facility
Unavailable
$15.07 higher than Austin for the office setting.
Poughkpsie/N Nyc Suburbs
New York · 88355
Office
$150.72
Facility
Unavailable
$5.84 higher than Austin for the office setting.
Queens
New York · 88355
Office
$158.98
Facility
Unavailable
$14.10 higher than Austin for the office setting.
Rest Of New York
New York · 88355
Office
$136.03
Facility
Unavailable
$8.85 lower than Austin for the office setting.
Ohio
Ohio · 88355
Office
$133.40
Facility
Unavailable
$11.48 lower than Austin for the office setting.
Oklahoma
Oklahoma · 88355
Office
$131.59
Facility
Unavailable
$13.29 lower than Austin for the office setting.
Portland
Oregon · 88355
Office
$149.78
Facility
Unavailable
$4.90 higher than Austin for the office setting.
Rest Of Oregon
Oregon · 88355
Office
$139.67
Facility
Unavailable
$5.21 lower than Austin for the office setting.
Metropolitan Philadelphia
Pennsylvania · 88355
Office
$144.80
Facility
Unavailable
$0.08 lower than Austin for the office setting.
Rest Of Pennsylvania
Pennsylvania · 88355
Office
$133.74
Facility
Unavailable
$11.14 lower than Austin for the office setting.
Puerto Rico
Puerto Rico · 88355
Office
$141.14
Facility
Unavailable
$3.74 lower than Austin for the office setting.
Rhode Island
Rhode Island · 88355
Office
$143.93
Facility
Unavailable
$0.95 lower than Austin for the office setting.
South Carolina
South Carolina · 88355
Office
$134.12
Facility
Unavailable
$10.76 lower than Austin for the office setting.
South Dakota**
South Dakota · 88355
Office
$139.62
Facility
Unavailable
$5.26 lower than Austin for the office setting.
Tennessee
Tennessee · 88355
Office
$132.62
Facility
Unavailable
$12.26 lower than Austin for the office setting.
Utah
Utah · 88355
Office
$135.43
Facility
Unavailable
$9.45 lower than Austin for the office setting.
Virginia
Virginia · 88355
Office
$138.64
Facility
Unavailable
$6.24 lower than Austin for the office setting.
Virgin Islands
United States Virgin Islands · 88355
Office
$141.14
Facility
Unavailable
$3.74 lower than Austin for the office setting.
Vermont
Vermont · 88355
Office
$139.00
Facility
Unavailable
$5.88 lower than Austin for the office setting.
Rest Of Washington
Washington · 88355
Office
$145.02
Facility
Unavailable
$0.14 higher than Austin for the office setting.
Seattle (King Cnty)
Washington · 88355
Office
$161.08
Facility
Unavailable
$16.20 higher than Austin for the office setting.
Wisconsin
Wisconsin · 88355
Office
$136.27
Facility
Unavailable
$8.61 lower than Austin for the office setting.
West Virginia
West Virginia · 88355
Office
$130.35
Facility
Unavailable
$14.53 lower than Austin for the office setting.
Wyoming**
Wyoming · 88355
Office
$140.02
Facility
Unavailable
$4.86 lower than Austin for the office setting.
See how rates vary across the country
88355 · Office / nonfacility · Non-QP. Choose a state to explore its payment localities. A range means the amount varies within that state.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$128.64
$175.04
Color shows the midpoint of each state’s locality range.
View all state and territory rates as a table
| State / territory | Rate range | Localities |
|---|---|---|
| AK | $175.04 | 1 |
| AL | $129.95 | 1 |
| AR | $128.64 | 1 |
| AZ | $137.69 | 1 |
| CA | $148.44–$181.42 | 29 |
| CO | $145.85 | 1 |
| CT | $147.79 | 1 |
| DC | $157.73 | 1 |
| DE | $139.53 | 1 |
| FL | $137.30–$145.06 | 3 |
| GA | $131.93–$141.93 | 2 |
| GU | $150.71 | 1 |
| HI | $150.71 | 1 |
| IA | $132.95 | 1 |
| ID | $133.42 | 1 |
| IL | $133.96–$143.62 | 4 |
| IN | $133.99 | 1 |
| KS | $132.19 | 1 |
| KY | $131.41 | 1 |
| LA | $131.14–$135.75 | 2 |
| MA | $145.24–$158.00 | 2 |
| MD | $141.75–$157.73 | 3 |
| ME | $133.57–$139.20 | 2 |
| MI | $133.53–$138.20 | 2 |
| MN | $141.87 | 1 |
| MO | $129.33–$136.49 | 3 |
| MS | $129.02 | 1 |
| MT | $140.28 | 1 |
| NC | $134.62 | 1 |
| ND | $139.69 | 1 |
| NE | $133.57 | 1 |
| NH | $143.40 | 1 |
| NJ | $150.07–$156.81 | 2 |
| NM | $133.91 | 1 |
| NV | $140.20 | 1 |
| NY | $136.03–$159.95 | 5 |
| OH | $133.40 | 1 |
| OK | $131.59 | 1 |
| OR | $139.67–$149.78 | 2 |
| PA | $133.74–$144.80 | 2 |
| PR | $141.14 | 1 |
| RI | $143.93 | 1 |
| SC | $134.12 | 1 |
| SD | $139.62 | 1 |
| TN | $132.62 | 1 |
| TX | $133.09–$144.88 | 8 |
| UT | $135.43 | 1 |
| VA | $138.64–$157.73 | 2 |
| VI | $141.14 | 1 |
| VT | $139.00 | 1 |
| WA | $145.02–$161.08 | 2 |
| WI | $136.27 | 1 |
| WV | $130.35 | 1 |
| WY | $140.02 | 1 |
Where does this rate apply?
Austin is a Medicare payment area. Our Census mapping connects it to 31 cities and communities in Texas, including the examples shown here.
Some communities span more than one payment area. Follow a city link to compare all of its mapped areas, or check the service-location ZIP above for an address-level starting point.
- 88355 in Austin
Multiple payment areas
- 88355 in Barton Creek
- 88355 in Bee Cave
- 88355 in Briarcliff
- 88355 in Cedar Park
Multiple payment areas
- 88355 in Creedmoor
Multiple payment areas
- 88355 in Elgin
Multiple payment areas
- 88355 in Garfield
Use this rate
What is a percentage of Medicare worth?
Turn a percentage into dollars for 88355 in Austin. This uses the base rate on this page, so the locality and release stay consistent.
Reference amount per service
$159.37
$144.88 × 110% = $159.37
A contract may specify another Medicare year or additional adjustments. This is percentage arithmetic on the displayed base rate, not a claim adjudication.
Working with a whole code list?
Compare an offer across your annual code mix, including an older Medicare schedule or flat per-code rates.
How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 88355 in Austin.
PPRRVU2026_Oct_nonQPP.csv
11,266
- Code
- 88355
- Physician work
- 1.80
- Practice expense
- 2.37
- Malpractice
- 0.03
GPCI2026.csv
96
- Locality
- Austin
- Physician work
- 1.002
- Practice expense
- 1.058
- Malpractice
- 0.886
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 1.80 | × 1.002 | 1.8036 |
| Practice expense | 2.37 | × 1.058 | 2.5075 |
| Malpractice | 0.03 | × 0.886 | 0.0266 |
| Total RVUs | 4.3376 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Austin$144.88
Open 88355 in the RVU calculator →
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 1.8 | 1.002 |
| Practice expense | 2.37 | 1.058 |
| Malpractice | 0.03 | 0.886 |
(1.8 × 1.002 + 2.37 × 1.058 + 0.03 × 0.886) × $33.4009 = $144.88
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
How this rate has changed
88355 · Office / nonfacility
$144.88
Effective 2026-10-01
The base rate is $3.63 higher than on 2025-10-01, moving from $141.25 to $144.88 (2.6%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$141.25changed to$144.88
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 1.85 changed to 1.80
- Practice expense RVU 2.38 changed to 2.37
- Work GPCI 1.000 changed to 1.002
- Practice expense GPCI 1.046 changed to 1.058
- Malpractice GPCI 0.914 changed to 0.886
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
Earliest loaded release: $141.25
Held through RVU25B, RVU25C, RVU25D.
Explore release dates and calculate this code in an earlier period →
Each row uses the accepted CMS release effective on that date and the same contractor and locality identifiers. Missing rates stay visible. Historical boundaries may differ; verify the service address for an older claim.
Inspect every release and its CMS source
| Effective from | Office / nonfacility | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $144.88 | Not available in this setting | RVU26D |
| 2026-07-01 | $144.88 | Not available in this setting | RVU26C |
| 2026-04-01 | $144.88 | Not available in this setting | RVU26B |
| 2026-01-01 | $144.88 | Not available in this setting | RVU26A |
| 2025-10-01 | $141.25 | Not available in this setting | RVU25D |
| 2025-07-01 | $141.25 | Not available in this setting | RVU25C |
| 2025-04-01 | $141.25 | Not available in this setting | RVU25B |
| 2025-01-01 | $141.25 | Not available in this setting | RVU25A |
88355 billing questions
How is 88355 different from routine muscle biopsy pathology?
Routine microscopic examination evaluates the biopsy for diagnosis. 88355 represents additional quantitative morphometric analysis of skeletal muscle tissue, so the record should support that distinct analysis.
When should 88355 be chosen instead of 88356?
Use 88355 for morphometric analysis of skeletal muscle. 88356 is the related analysis code for nerve tissue.
Can 88355 be reported with the muscle biopsy pathology code?
Both may be reported when the muscle biopsy receives routine surgical pathology examination and a separately performed morphometric analysis. The documentation should show both services.
Which modifiers identify the components?
Modifier 26 identifies the professional interpretation, and modifier TC identifies the technical service. Without either modifier, the claim represents the global service.
What documentation supports 88355?
Document the skeletal muscle specimen, the quantitative morphometric work performed, the findings, and the pathologist's interpretation.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
