Choose 46607 when the biopsy is performed during high-resolution magnified anoscopy. Choose 46606 for anoscopy with biopsy without that high-resolution component.
On this page
CMS RVU26D · Effective 2026-10-01
46607 Anoscopy Medicare reimbursement rates in Colorado
High-resolution anoscopy with biopsy examines the anal canal under magnification and collects tissue from suspicious areas, such as lesions evaluated for anal dysplasia. Compare 46607 office and facility rates across CMS payment localities in Colorado.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 46607 in Colorado?
Colorado has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$239.00
1 of 1 localities have a supported rate.
Payment area: Colorado
One mapped payment locality.
Facility setting
$113.91
1 of 1 localities have a supported rate.
Payment area: Colorado
One mapped payment locality.
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Anoscopy
About 46607: High-resolution anoscopy with biopsy
High-resolution anoscopy with biopsy examines the anal canal under magnification and collects tissue from suspicious areas, such as lesions evaluated for anal dysplasia.
This service uses high-resolution magnification to inspect the anal canal and obtain one or more tissue samples from areas that look abnormal. It is commonly performed by colorectal surgeons and other clinicians trained in high-resolution anoscopy to evaluate findings such as abnormal anal cytology or suspected anal dysplasia. The magnified examination helps identify areas for biopsy; routine anoscopy with biopsy does not include this high-resolution component.
Report the code when the documented service includes both high-resolution anoscopy and biopsy. The record should identify the reason for examination, use of magnification, relevant findings, biopsy sites, and whether tissue was collected. The 0-day global period includes same-day preoperative and postoperative care. When related endoscopies are performed together, endoscopy-family pricing applies. A bilateral modifier is inappropriate. Medicare does not pay an assistant at surgery for this service, and co-surgeons and team surgery are not permitted.
CMS billing rules for 46607
- Global period
- Minor procedure with a 0-day global period: same-day preoperative and postoperative care is included.
- Multiple procedures
- Endoscopy family pricing applies when related endoscopies are performed together.
- Bilateral procedures
- Bilateral adjustment does not apply; the descriptor or anatomy makes modifier 50 inappropriate.
- Assistant at surgery
- Statutory restriction: assistant at surgery is not paid.
- Co-surgeons
- Co-surgeons not permitted.
- Team surgery
- Team surgery not permitted.
Where the value comes from
- Work RVU2.15 · 31%
- Practice expense (office) RVU4.46 · 65%
- Malpractice RVU0.30 · 4%
2.9K
Medicare services in 2024 · #2199 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
46607 compared with similar codes
Office rates for Colorado, from the same CMS release.
46601 describes high-resolution anoscopy without biopsy. When tissue is collected during the high-resolution examination, 46607 captures the combined service.
46600 is diagnostic anoscopy without high-resolution magnification or biopsy. It does not represent the magnified examination and tissue collection included in 46607.
Compare 46607 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Colorado →
Office / nonfacility
$239.00
Facility
$113.91
Need rates for a whole code list?
Fee-sheet and API access are in early access. Tell us which codes and locations your team needs.
How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 46607 in Colorado.
PPRRVU2026_Oct_nonQPP.csv
5,602
- Code
- 46607
- Physician work
- 2.15
- Practice expense
- 4.46
- Malpractice
- 0.30
GPCI2026.csv
37
- Locality
- Colorado
- Physician work
- 1.012
- Practice expense
- 1.064
- Malpractice
- 0.781
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 2.15 | × 1.012 | 2.1758 |
| Practice expense | 4.46 | × 1.064 | 4.7454 |
| Malpractice | 0.30 | × 0.781 | 0.2343 |
| Total RVUs | 7.1555 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Colorado$239.00
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 2.15 | 1.012 |
| Practice expense | 4.46 | 1.064 |
| Malpractice | 0.3 | 0.781 |
(2.15 × 1.012 + 4.46 × 1.064 + 0.3 × 0.781) × $33.4009 = $239.00
Facility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 2.15 | 1.012 |
| Practice expense | 0.94 | 1.064 |
| Malpractice | 0.3 | 0.781 |
(2.15 × 1.012 + 0.94 × 1.064 + 0.3 × 0.781) × $33.4009 = $113.91
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
46607 billing questions
How does this differ from anoscopy with biopsy without high-resolution magnification?
This code includes high-resolution magnification as well as biopsy. Use the standard anoscopy biopsy code when biopsy is performed without that magnified examination.
Can the high-resolution examination be reported separately when a biopsy is taken?
The biopsy code includes the high-resolution examination. Do not separately report the high-resolution anoscopy-only service for the same examination.
Does the code include pathology analysis of the biopsy?
It covers the anoscopy and tissue collection, not the laboratory’s histologic examination of the specimen. Pathology may be reported by the provider or laboratory performing that separate service.
How many units are reported when multiple areas are biopsied?
The code covers single or multiple biopsies during the high-resolution anoscopy session; the number of tissue samples does not determine units.
Can modifier 50 or an assistant-at-surgery modifier be used?
No. CMS identifies bilateral adjustment as inappropriate for this code and does not pay an assistant at surgery for it.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
