$135.40
Q4198 identifies Genesis amnio membrane, while Q4199 identifies Cygnus Matrix. Select the code matching the product supplied, not merely the wound area.
On this page
CMS RVU26D · Effective 2026-10-01
Q4199 Wound matrix Medicare reimbursement rates in Colorado
Report Q4199 for each square centimeter of Cygnus Matrix supplied with a primary wound procedure involving application of a skin substitute. Compare Q4199 office and facility rates across CMS payment localities in Colorado.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4199 in Colorado?
Colorado has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$135.40
1 of 1 localities have a supported rate.
Payment area: Colorado
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Wound care supply
About Q4199: Cygnus wound matrix supply
Report Q4199 for each square centimeter of Cygnus Matrix supplied with a primary wound procedure involving application of a skin substitute.
Q4199 identifies the Cygnus Matrix product used in wound care, measured by the area supplied in square centimeters. It represents the product, not the clinician’s work of preparing the wound or applying the matrix. Clinicians may use it when treating an appropriate wound in an outpatient or other setting where the product is supplied and applied as part of wound management.
This is an add-on code: report it only with an appropriate primary procedure, and Medicare pays it within that procedure’s global period. Document the product and the square centimeters supplied, along with the treated wound and the primary procedure. CMS assigns Q4199 technical-component-only status; a separate code covers interpretation. The code has no physician work RVUs in the supplied CMS facts, so its valuation is not based on separately reported physician work.
CMS billing rules for Q4199
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4199 compared with similar codes
Office rates for Colorado, from the same CMS release.
$135.40
Q4195 identifies PuraPly; Q4199 identifies Cygnus Matrix. These are separate product-specific supply codes and are not interchangeable based on similar use or measurement.
$163.58
15271 reports the primary skin-substitute application service for specified sites and wound areas. Q4199 reports the Cygnus Matrix product supplied per square centimeter and is add-on only.
Compare Q4199 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Colorado →
Office / nonfacility
$135.40
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for Q4199 in Colorado.
PPRRVU2026_Oct_nonQPP.csv
18,291
- Code
- Q4199
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
37
- Locality
- Colorado
- Physician work
- 1.012
- Practice expense
- 1.064
- Malpractice
- 0.781
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.012 | 0.0000 |
| Practice expense | 3.81 | × 1.064 | 4.0538 |
| Malpractice | 0.00 | × 0.781 | 0.0000 |
| Total RVUs | 4.0538 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Colorado$135.40
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0 | 1.012 |
| Practice expense | 3.81 | 1.064 |
| Malpractice | 0 | 0.781 |
(0 × 1.012 + 3.81 × 1.064 + 0 × 0.781) × $33.4009 = $135.40
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
Q4199 billing questions
How is the number of Q4199 units determined?
Report the square centimeters of Cygnus Matrix supplied. The record should support the product used and the measured amount.
Can Q4199 be billed by itself?
No. CMS identifies it as an add-on code, so it must be billed with an appropriate primary procedure.
Which primary procedure may accompany Q4199?
Use the applicable wound procedure for the treatment performed, such as a skin-substitute application code when that procedure describes the service. The wound site and extent determine the appropriate application code.
Is Q4199 the code for applying the matrix?
No. Q4199 represents the Cygnus Matrix product per square centimeter; the primary procedure reports the wound treatment or application service.
What documentation supports Q4199?
Record the wound treated, the Cygnus Matrix product supplied, the square centimeters used, and the associated primary procedure.
How does the global-period rule affect Q4199?
Medicare pays Q4199 within the global period of the primary procedure with which it is reported.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,288Q4196,,Puraply am 1 sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,289Q4197,,Puraply xt 1 sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,290Q4198,,Genesis amnio membrane 1sqcm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,291Q4199,,"Cygnus matrix, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,292Q4200,,Skin te 1 sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,293Q4201,,Matrion 1 sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,294Q4202,,"Keroxx (2.5g/cc), 1cc",C,,0.00,0.00,,0.00,,0.00,0.00,0.00,3,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
3401112,CA,69,VISALIA,1.017,1.096,0.536
3501112,CA,70,YUBA CITY,1.017,1.096,0.536
3601112,CA,75,REST OF CALIFORNIA,1.017,1.096,0.536
3704112,CO,01,COLORADO,1.012,1.064,0.781
3813102,CT,00,CONNECTICUT,1.020,1.077,1.210
3912202,DC,01,DC + MD/VA SUBURBS,1.054,1.178,1.113
4012102,DE,01,DELAWARE,1.005,0.988,0.899