CPT 52287: Bladder chemodenervationMedicare rate & RVUs in Guam

Reports cystoscopic injection of a chemodenervation agent into the bladder for conditions such as overactive bladder or neurogenic detrusor overactivity.

CMS RVU26DEffective Oct 1, 20261 payment locality84K Medicare services in 2024

Medicare pays $391.28 for 52287 in the office in Guam (Hawaii, Guam). Which amount applies depends on the service address.

$391.28Office (non-facility)
$147.09Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 52287 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Guam
  2. What 52287 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 52287 covers

A urologist typically performs this procedure by passing a cystoscope through the urethra and injecting a chemodenervation agent into the bladder wall. Common indications include overactive bladder with inadequate response or intolerance to medication and neurogenic detrusor overactivity. The code represents the cystoscopic injection service, not a biopsy or treatment of a bladder lesion. When the practice supplies onabotulinumtoxinA, the drug may be reported separately using the applicable drug code.

Report the service for the cystoscopic chemodenervation session; document the indication, agent and dose, injection sites, and procedure performed. The procedure has a 0-day global period, so same-day preoperative and postoperative care is included. When related endoscopies are performed together, endoscopy-family pricing applies. Modifier 50 is inappropriate for this service. Medicare does not pay an assistant at surgery, and co-surgeon and team-surgery reporting are not permitted. The physician fee schedule has different practice-expense inputs for office and facility settings.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

52287 in Hawaii, Guam

52287 office and facility rates by payment locality
Payment localityOfficeFacility
Hawaii, Guam$391.28$147.09

How the 52287 rate is calculated

Each of 52287’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 52287

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 3.12Practice expense 7.34Malpractice 0.43

10.8900 adjusted RVUs×$33.4009 conversion factor=$363.74

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 52287

The CMS indicators that decide how 52287 is paid alongside other services.

CMS payment indicators · 52287

Bladder chemodenervation

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

52287 without 51 · national office

$363.74

Bladder chemodenervation

52287-51 · Second procedure: 50%

$181.87

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

52287 compared with similar codes

Compare codes

52287 vs 52204 vs 52224 vs 52214: national Medicare rates

Swap in your local Medicare rate.

  • 52287
    Bladder chemodenervation · 3.12 wRVU
    $363.74
  • 52204
    Cystoscopic biopsy · 2.53 wRVU
    $355.39−$8.35
  • 52224
    Bladder lesion treatment · 3.95 wRVU
    $760.20+$396.46
  • 52214
    Cystoscopy treatment · 3.41 wRVU
    $727.47+$363.73

How to choose

52204Cystoscopic biopsy
Use 52287 for bladder chemodenervation injections. Use 52204 when the cystoscopy includes biopsy of bladder tissue.
52224Bladder lesion treatment
52287 describes injection for bladder chemodenervation; 52224 is for cystoscopic treatment of a bladder lesion.
52214Cystoscopy treatment
52287 involves injections into the bladder wall for chemodenervation. 52214 is used for cystoscopic fulguration or other treatment at specified urinary-tract sites.

52287 billing questions

How is this different from cystoscopy with biopsy?

52287 reports injections intended to chemodenervate the bladder. A biopsy code is for sampling bladder tissue, not for the therapeutic injection.

Can the medication be reported separately?

When the practice supplies onabotulinumtoxinA, report the drug separately using the applicable drug code. The cystoscopic injection service is reported with 52287.

Should modifier 50 be appended?

No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.

What happens when another related endoscopy is performed at the same session?

CMS endoscopy-family pricing applies when related endoscopies are performed together. Documentation should identify each distinct service performed.

What documentation supports 52287?

Document the bladder condition being treated, the chemodenervation agent and dose, the cystoscopic injection procedure, and the sites treated.

Can an assistant or co-surgeon be reported?

Medicare does not pay an assistant at surgery for this service. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 52287PPRRVU2026_Oct_nonQPP.csv, line 6,129 (RVU26D)
Geographic factors for Hawaii, GuamGPCI2026.csv, line 46 (RVU26D)

Open CMS sourceHow we calculate rates

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