$116.44
Q4388 identifies Neothelium 4L; Q4389 identifies Neothelium 4L+. Match the code to the specific product supplied.
On this page
CMS RVU26D · Effective 2026-10-01
Q4389 Wound matrix Medicare reimbursement rates in Iowa
Reports Neothelium 4L+ wound matrix by square centimeter when supplied for application to a wound with a separately reported primary procedure. Compare Q4389 office and facility rates across CMS payment localities in Iowa.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4389 in Iowa?
Iowa has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$116.44
1 of 1 localities have a supported rate.
Payment area: Iowa
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Skin substitute
About Q4389: Neothelium 4L+ wound matrix supply
Reports Neothelium 4L+ wound matrix by square centimeter when supplied for application to a wound with a separately reported primary procedure.
Q4389 represents the Neothelium 4L+ wound matrix product, measured by the square centimeter. It identifies the material supplied for wound coverage; it is not the clinician’s wound-preparation or application service. Wound-care physicians, podiatrists, and surgeons may use a matrix product during treatment of wounds that require coverage, with the application performed in an office, clinic, or facility setting.
Report the product code with the applicable primary procedure, not by itself. The clinical record should support the product used and the amount represented by the billed units. CMS classifies Q4389 as an add-on code, so payment is within the primary procedure’s global period. It is also technical-component-only; any separately reportable interpretation is represented by its own code rather than Q4389. The product code and the wound application service describe distinct parts of the treatment.
CMS billing rules for Q4389
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4389 compared with similar codes
Office rates for Iowa, from the same CMS release.
$116.44
Q4387 identifies Neothelium full thickness, while Q4389 identifies Neothelium 4L+. These are different product variants.
$145.07
15271 reports a wound application service, not the Neothelium product itself. Q4389 identifies the product and is reported with an applicable primary procedure.
Compare Q4389 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Iowa →
Office / nonfacility
$116.44
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for Q4389 in Iowa.
PPRRVU2026_Oct_nonQPP.csv
18,474
- Code
- Q4389
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
53
- Locality
- Iowa
- Physician work
- 1.000
- Practice expense
- 0.915
- Malpractice
- 0.397
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.000 | 0.0000 |
| Practice expense | 3.81 | × 0.915 | 3.4862 |
| Malpractice | 0.00 | × 0.397 | 0.0000 |
| Total RVUs | 3.4862 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Iowa$116.44
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0 | 1 |
| Practice expense | 3.81 | 0.915 |
| Malpractice | 0 | 0.397 |
(0 × 1 + 3.81 × 0.915 + 0 × 0.397) × $33.4009 = $116.44
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
Q4389 billing questions
How is Q4389 different from Q4388?
Both identify Neothelium products billed by square centimeter, but Q4389 specifies the 4L+ product, while Q4388 identifies Neothelium 4L. Select the code matching the product supplied.
Can Q4389 be billed without a wound application procedure?
No. CMS identifies Q4389 as an add-on code that must be billed with a primary procedure; it is paid within that procedure’s global period.
Is the product included in the application code?
Q4389 identifies the product, while the primary procedure represents the wound application service. Report the applicable codes together when the product is used with that procedure.
How should units be supported?
The code is measured per square centimeter. Documentation should identify Neothelium 4L+ and support the square-centimeter amount represented by the units billed.
Does Q4389 include professional interpretation?
No. CMS classifies Q4389 as technical-component-only; any separately reportable interpretation is represented by a separate code.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,471Q4386,,Acesso trifaca per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,472Q4387,,Neothelium ft per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,473Q4388,,Neothelium 4l per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,474Q4389,,Neothelium 4l+ per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,475Q4390,,Ascendion per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,476Q4391,,Amnioplast double per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,477Q4392,,Grafix duo per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
5006102,IL,15,SUBURBAN CHICAGO,1.007,1.027,1.772
5106102,IL,99,REST OF ILLINOIS,1.000,0.913,1.563
5208102,IN,00,INDIANA,1.000,0.927,0.486
5305102,IA,00,IOWA,1.000,0.915,0.397
5405202,KS,00,KANSAS,1.000,0.904,0.504
5515102,KY,00,KENTUCKY,1.000,0.889,0.915
5607202,LA,01,NEW ORLEANS,1.000,0.941,1.136