$150.00–$159.22
15271 describes applying a skin substitute to a qualifying trunk, arm, or leg wound. Q4301 identifies the Activate Matrix product used with the primary procedure.
On this page
CMS RVU26D · Effective 2026-10-01
Q4301 Wound matrix Medicare reimbursement rates in Michigan
Q4301 reports Activate Matrix by square centimeter when a clinician applies this specific matrix as part of a wound treatment procedure. Compare Q4301 office and facility rates across CMS payment localities in Michigan.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4301 in Michigan?
Michigan has 2 payment localities in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the 2 payment areas shown below, using the same CMS release.
Office / nonfacility
$116.19–$122.80
2 of 2 localities have a supported rate.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Wound care
About Q4301: Activate Matrix wound graft, per square centimeter
Q4301 reports Activate Matrix by square centimeter when a clinician applies this specific matrix as part of a wound treatment procedure.
Activate Matrix is a named wound matrix supplied for placement on a prepared wound bed. A wound-care clinician may use it during a skin-substitute application procedure, such as treatment of a lower-extremity wound. Q4301 identifies the product, not the work of preparing the wound and applying the matrix. The record should identify Activate Matrix by name and show where it was placed.
Report Q4301 in square-centimeter units supported by the product-use record, rather than counting wounds or packages. Document the wound location and measurements, the amount of Activate Matrix used, and the associated application procedure. CMS classifies Q4301 as an add-on code: it is billed with a primary procedure, and its payment falls within that procedure’s global period. CMS also designates Q4301 as technical-component-only; a separately reportable interpretation is represented by another code, not by Q4301. Select a different product code if the material used was not Activate Matrix.
CMS billing rules for Q4301
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4301 compared with similar codes
Office rates for Michigan, from the same CMS release.
$152.99–$161.61
15275 describes applying a skin substitute to qualifying sites that include the foot. Q4301 identifies the Activate Matrix product, measured in square centimeters.
$116.19–$122.80
Both are product-specific, square-centimeter codes. Use Q4301 for documented Activate Matrix and Q4309 for Via Matrix.
Compare Q4301 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
2 of 2 payment localities
Detroit →
Office / nonfacility
$122.80
Facility
Unavailable
Rest Of Michigan →
Office / nonfacility
$116.19
Facility
Unavailable
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Q4301 billing questions
When is Q4301 reported with a skin-substitute application code?
Report Q4301 for the Activate Matrix product when it is used with the documented primary application procedure. The application work is represented by the procedure code, not by Q4301.
How are units determined for Q4301?
Each unit represents one square centimeter of Activate Matrix. Use the documented product amount to support the units rather than the number of wounds treated.
Can Q4301 be billed by itself?
No. CMS classifies it as an add-on code billed with a primary procedure; its payment is within that procedure’s global period.
Does Q4301 include interpretation?
No. CMS designates Q4301 as technical-component-only and identifies a separate code for interpretation.
How does Q4301 differ from Q4309?
Choose by the product actually documented: Q4301 identifies Activate Matrix, while Q4309 identifies Via Matrix.
What documentation distinguishes Q4301 from other wound-product codes?
The record should name Activate Matrix, identify the treated site, and support the square centimeters billed. A generic entry such as “wound matrix applied” does not identify this product.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,385Q4298,,"Amniocore pro, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,386Q4299,,"Amniocore pro+, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,387Q4300,,"Acesso tl, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,388Q4301,,"Activate matrix, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,389Q4302,,"Complete aca, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,390Q4303,,"Complete aa, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,391Q4304,,"Grafix plus, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00