38227
No office rateCar-t receipt&prepj admn
Use 38227 for receipt and preparation of the CAR T-cell product; use 38228 for administering it to the patient.
On this page
CMS RVU26D · Effective 2026-10-01
38228 CAR T-cell administration Medicare reimbursement rates in Minnesota
Report this service for administering a patient’s own genetically modified T cells as CAR T-cell therapy, rather than for collecting or preparing the cells. Compare 38228 office and facility rates across CMS payment localities in Minnesota.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 38228 in Minnesota?
Minnesota has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$320.43
1 of 1 localities have a supported rate.
Payment area: Minnesota
One mapped payment locality.
Facility setting
$146.52
1 of 1 localities have a supported rate.
Payment area: Minnesota
One mapped payment locality.
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Cell therapy
About 38228: Autologous CAR T-cell administration
Report this service for administering a patient’s own genetically modified T cells as CAR T-cell therapy, rather than for collecting or preparing the cells.
This code identifies the administration step of autologous chimeric antigen receptor (CAR) T-cell therapy. A patient’s T lymphocytes are collected and modified for treatment, then the resulting cell product is administered back to that patient. Hematologists, oncologists, and other clinicians involved in cellular therapy typically oversee the infusion in a hospital or specialized treatment setting. The code is specific to CAR T-cell administration, not conventional chemotherapy or hematopoietic stem-cell transplantation.
Select the code for the actual administration of the autologous CAR T-cell product. Collection and preparation activities occur at different stages and are represented by separate codes in the CAR T sequence when applicable. Documentation should identify the autologous CAR T product and record that it was administered, including the date and supporting infusion documentation. CMS assigns physician work, practice expense, and malpractice relative values to the service; no additional payment rule is listed in the supplied CMS facts.
Where the value comes from
- Work RVU3.00 · 31%
- Practice expense (office) RVU6.35 · 66%
- Malpractice RVU0.20 · 2%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
38228 compared with similar codes
Office rates for Minnesota, from the same CMS release.
38226
No office rateCar-t prep t lymphcyt f/trns
38226 concerns preparing blood-derived T lymphocytes for transport. 38228 concerns administering the completed autologous CAR T-cell product.
38241
No office rateTransplt autol hct/donor
38241 describes autologous hematopoietic cell transplantation. 38228 is specific to administration of autologous CAR T cells.
Compare 38228 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Minnesota →
Office / nonfacility
$320.43
Facility
$146.52
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 38228 in Minnesota.
PPRRVU2026_Oct_nonQPP.csv
4,728
- Code
- 38228
- Physician work
- 3.00
- Practice expense
- 6.35
- Malpractice
- 0.20
GPCI2026.csv
66
- Locality
- Minnesota
- Physician work
- 1.000
- Practice expense
- 1.029
- Malpractice
- 0.296
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 3.00 | × 1.000 | 3.0000 |
| Practice expense | 6.35 | × 1.029 | 6.5341 |
| Malpractice | 0.20 | × 0.296 | 0.0592 |
| Total RVUs | 9.5934 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Minnesota$320.43
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 3 | 1 |
| Practice expense | 6.35 | 1.029 |
| Malpractice | 0.2 | 0.296 |
(3 × 1 + 6.35 × 1.029 + 0.2 × 0.296) × $33.4009 = $320.43
Facility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 3 | 1 |
| Practice expense | 1.29 | 1.029 |
| Malpractice | 0.2 | 0.296 |
(3 × 1 + 1.29 × 1.029 + 0.2 × 0.296) × $33.4009 = $146.52
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
38228 billing questions
How is 38228 different from 38227?
38228 identifies administration of the autologous CAR T-cell product. 38227 describes receipt and preparation of the product for administration, a distinct step.
Does 38228 cover cell collection or preparation?
No. It represents administration, not collection of the patient’s T cells or preparation of cells for transport or infusion.
What documentation supports reporting 38228?
Document that the product was autologous CAR T cells and that administration occurred. The infusion record should support the date and service performed.
Is 38228 reported for CAR T-cell collection?
No. Collection is a separate service; 38228 is selected for the later administration of the CAR T-cell product.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
4,72538225,,Car-t hrv bld-drv t lymphcyt,B,+,1.89,0.41,NA,0.41,,0.20,2.50,2.50,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
4,72638226,,Car-t prep t lymphcyt f/trns,B,+,0.77,0.17,NA,0.17,,0.07,1.01,1.01,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
4,72738227,,Car-t receipt&prepj admn,B,+,0.78,0.17,NA,0.17,,0.07,1.02,1.02,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
4,72838228,,Car-t admn autologous,A,,3.00,6.35,,1.29,,0.20,9.55,4.49,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
4,72938230,,Bone marrow harvest allogen,A,,3.41,1.08,NA,1.08,,0.72,5.21,5.21,0,000,0.00,0.00,0.00,2,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
4,73038232,,Bone marrow harvest autolog,A,,3.41,0.87,NA,0.87,,0.45,4.73,4.73,0,000,0.00,0.00,0.00,2,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
4,73138240,,Transplt allo hct/donor,R,,3.90,1.89,NA,1.89,,0.25,6.04,6.04,0,XXX,0.00,0.00,0.00,2,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
6314212,MA,99,REST OF MASSACHUSETTS,1.016,1.053,0.797
6408202,MI,01,DETROIT,1.000,0.965,1.686
6508202,MI,99,REST OF MICHIGAN,1.000,0.913,1.129
6606202,MN,00,MINNESOTA,1.000,1.029,0.296
6707302,MS,00,MISSISSIPPI,1.000,0.861,0.739
6805302,MO,02,METROPOLITAN KANSAS CITY,1.000,0.939,0.977
6905302,MO,01,METROPOLITAN ST. LOUIS,1.000,0.952,1.002