Both describe screening colonoscopy, but G0105 is for patients classified as high risk; G0121 is for those not classified as high risk.
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CMS RVU26D · Effective 2026-10-01
G0121 Screening colonoscopy Medicare reimbursement rates in Minnesota
Report G0121 for a colorectal cancer screening colonoscopy performed for an individual who is not classified as high risk. Compare G0121 office and facility rates across CMS payment localities in Minnesota.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for G0121 in Minnesota?
Minnesota has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$376.04
1 of 1 localities have a supported rate.
Payment area: Minnesota
One mapped payment locality.
Facility setting
$156.42
1 of 1 localities have a supported rate.
Payment area: Minnesota
One mapped payment locality.
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Colorectal screening
About G0121: Average-risk screening colonoscopy
Report G0121 for a colorectal cancer screening colonoscopy performed for an individual who is not classified as high risk.
G0121 represents a colonoscopy performed for colorectal cancer screening when the patient is not classified as high risk. A gastroenterologist, surgeon, or other qualified practitioner advances a colonoscope through the large bowel to examine the colon for abnormalities. The service may be performed in a physician office or a facility, such as an ambulatory surgery center or hospital outpatient department.
Select G0121 based on the screening indication and the patient’s risk classification, not simply because a colonoscopy occurred. The record should support screening intent and include the procedure findings and extent of examination. CMS assigns a 0-day global period, so same-day preoperative and postoperative care is included. Modifier 53 has separate pricing treatment. When multiple procedures occur in one session, the highest-valued procedure is paid in full and others at 50%. Do not report modifier 50; assistant-at-surgery payment is restricted, and co-surgeons and team surgery are not permitted.
CMS billing rules for G0121
- Global period
- Minor procedure with a 0-day global period: same-day preoperative and postoperative care is included.
- Multiple procedures
- Standard multiple procedure reduction: the highest-valued procedure is paid in full and others at 50% when performed in the same session.
- Bilateral procedures
- Bilateral adjustment does not apply; the descriptor or anatomy makes modifier 50 inappropriate.
- Assistant at surgery
- Statutory restriction: assistant at surgery is not paid.
- Co-surgeons
- Co-surgeons not permitted.
- Team surgery
- Team surgery not permitted.
Where the value comes from
- Work RVU3.18 · 28%
- Practice expense (office) RVU7.73 · 68%
- Malpractice RVU0.42 · 4%
301.6K
Medicare services in 2024 · #310 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
G0121 compared with similar codes
Office rates for Minnesota, from the same CMS release.
G0104 reports screening by flexible sigmoidoscopy. G0121 reports screening by colonoscopy, which examines the colon more extensively.
G0121 identifies a screening colonoscopy for a patient who is not high risk. CPT 45378 is used for a diagnostic colonoscopy when the clinical indication is diagnostic rather than screening.
Compare G0121 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Minnesota →
Office / nonfacility
$376.04
Facility
$156.42
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for G0121 in Minnesota.
PPRRVU2026_Oct_nonQPP.csv
15,093
- Code
- G0121
- Physician work
- 3.18
- Practice expense
- 7.73
- Malpractice
- 0.42
GPCI2026.csv
66
- Locality
- Minnesota
- Physician work
- 1.000
- Practice expense
- 1.029
- Malpractice
- 0.296
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 3.18 | × 1.000 | 3.1800 |
| Practice expense | 7.73 | × 1.029 | 7.9542 |
| Malpractice | 0.42 | × 0.296 | 0.1243 |
| Total RVUs | 11.2585 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Minnesota$376.04
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 3.18 | 1 |
| Practice expense | 7.73 | 1.029 |
| Malpractice | 0.42 | 0.296 |
(3.18 × 1 + 7.73 × 1.029 + 0.42 × 0.296) × $33.4009 = $376.04
Facility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 3.18 | 1 |
| Practice expense | 1.34 | 1.029 |
| Malpractice | 0.42 | 0.296 |
(3.18 × 1 + 1.34 × 1.029 + 0.42 × 0.296) × $33.4009 = $156.42
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
G0121 billing questions
When should G0121 be selected instead of G0105?
Use G0121 for a screening colonoscopy when the patient is not classified as high risk. G0105 is the corresponding screening code for a high-risk individual.
How does G0121 differ from G0104?
G0121 is for screening by colonoscopy. G0104 represents screening by flexible sigmoidoscopy, which examines a more limited portion of the colon.
What documentation supports G0121?
Document that the examination was for colorectal cancer screening and support the patient’s not-high-risk classification. The procedure report should describe the examination and its findings.
What does modifier 53 mean for this code?
Modifier 53 identifies a discontinued procedure, and CMS assigns it separate pricing treatment for G0121. The record should explain why the colonoscopy was discontinued.
Can G0121 be billed with modifier 50?
No. Do not append modifier 50 to this colonoscopy service.
How are multiple procedures in the same session paid?
CMS pays the highest-valued procedure in full and pays other procedures at 50% when multiple procedures are performed in the same session.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
