$70.04–$77.30
88182 describes a limited cell-marker analysis, such as DNA ploidy or immunocytochemistry. 88184 is the technical component for the first marker in a flow cytometry study.
On this page
CMS RVU26D · Effective 2026-10-01
88182 Cell marker study Medicare reimbursement rates in Missouri
Reports a limited cell-marker analysis, such as DNA ploidy, cell-cycle analysis, or immunocytochemistry, on a specimen submitted for diagnostic evaluation. Compare 88182 office and facility rates across CMS payment localities in Missouri.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 88182 in Missouri?
Missouri has 3 payment localities in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the 3 payment areas shown below, using the same CMS release.
Office / nonfacility
$132.09–$143.12
3 of 3 localities have a supported rate.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Where 88182 pays more and less in Missouri
3 payment localities
$132.09 to $143.12
Laboratory pathology
About 88182: Limited cell marker study
Reports a limited cell-marker analysis, such as DNA ploidy, cell-cycle analysis, or immunocytochemistry, on a specimen submitted for diagnostic evaluation.
This service covers a limited analysis of cells using markers or related measurements, including DNA ploidy, cell-cycle analysis, or immunocytochemistry. It is performed in a pathology or cytology laboratory, with laboratory staff and equipment supporting the technical work and a pathologist or other qualified professional interpreting the findings. It may be used to characterize tumor cells or other diagnostically relevant cells in a submitted specimen.
Report the service for each specimen that receives the limited study, rather than counting individual markers as separate units. Documentation should identify the specimen, the type and purpose of the analysis, and the resulting interpretation. CMS recognizes separate professional and technical components: modifier 26 identifies interpretation, modifier TC identifies the equipment and staff portion, and reporting without either modifier represents the global service. The professional and technical components are separately priced when billed with their respective modifiers.
CMS billing rules for 88182
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU0.75 · 17%
- Practice expense (office) RVU3.65 · 82%
- Malpractice RVU0.06 · 1%
2.3K
Medicare services in 2024 · #2361 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
88182 compared with similar codes
Office rates for Missouri, from the same CMS release.
$33.66–$34.59
88187 is the professional interpretation and report for flow cytometry with 2–8 markers. 88182 describes a limited cell-marker study, not a marker-count tier for flow cytometry.
$56.00–$57.62
88188 reports flow cytometry interpretation for 9–15 markers; 88182 is used for a limited cell-marker analysis such as cell-cycle analysis or immunocytochemistry.
Compare 88182 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
3 of 3 payment localities
Metropolitan Kansas City →
Office / nonfacility
$141.49
Facility
Unavailable
Metropolitan St. Louis →
Office / nonfacility
$143.12
Facility
Unavailable
Rest Of Missouri →
Office / nonfacility
$132.09
Facility
Unavailable
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88182 billing questions
When should 88182 be chosen instead of a flow cytometry code?
Use 88182 for a limited cell-marker study such as DNA ploidy, cell-cycle analysis, or immunocytochemistry. Flow cytometry procedures are reported with codes specific to their technical marker work and interpretation.
How many units should be reported?
Report one unit for each specimen receiving the limited study. Do not use the number of markers as the unit count.
Can the professional and technical portions be billed separately?
Yes. Modifier 26 identifies the professional interpretation, and modifier TC identifies the technical work. Without either modifier, the claim represents the global service.
What documentation supports 88182?
Document the specimen, the limited study performed, its diagnostic purpose, and the interpretation. The record should make clear that the work was a limited cell-marker analysis rather than flow cytometry marker testing.
Is 88182 reported once per marker?
No. For this code, the unit is the specimen receiving the limited analysis, not each marker assessed.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
11,15688177,,Cytp fna eval ea addl,A,,0.41,0.45,,0.45,NA,0.01,0.87,0.87,1,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,15788177,26,Cytp fna eval ea addl,A,,0.41,0.19,,0.19,,0.01,0.61,0.61,1,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,15888177,TC,Cytp fna eval ea addl,A,,0.00,0.26,,0.26,NA,0.00,0.26,0.26,1,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,15988182,,Cell marker study,A,,0.75,3.65,,3.65,NA,0.06,4.46,4.46,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,16088182,26,Cell marker study,A,,0.75,0.29,,0.29,,0.01,1.05,1.05,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,16188182,TC,Cell marker study,A,,0.00,3.36,,3.36,NA,0.05,3.41,3.41,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
11,16288184,,Flowcytometry/ tc 1 marker,A,,0.00,2.41,,2.41,NA,0.02,2.43,2.43,3,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00