$18.45–$20.15
95144 is for single-dose vials. 95165 is for multidose vials, with Medicare units based on 1 mL aliquots from each vial.
On this page
CMS RVU26D · Effective 2026-10-01
95165 Allergy extract preparation Medicare reimbursement rates in Missouri
Physician-supervised preparation of allergen extract in multidose vials for allergy shots, reported by doses prepared rather than injections administered. Compare 95165 office and facility rates across CMS payment localities in Missouri.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 95165 in Missouri?
Missouri has 3 payment localities in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the 3 payment areas shown below, using the same CMS release.
Office / nonfacility
$15.29–$16.65
3 of 3 localities have a supported rate.
Facility setting
$2.62–$2.66
3 of 3 localities have a supported rate.
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Where 95165 pays more and less in Missouri
3 payment localities
$15.29 to $16.65
Allergy and immunology
About 95165: Multidose allergen immunotherapy extract preparation
Physician-supervised preparation of allergen extract in multidose vials for allergy shots, reported by doses prepared rather than injections administered.
This service covers an allergist's selection of allergens and concentrations and supervision of custom extract preparation in multidose vials. Allergy and immunology practices typically prepare extracts after testing and clinical history identify relevant sensitivities to pollens, molds, dust mites, or animal dander. The preparing practice may administer the shots or send the extract to another office, such as a primary care clinic. Preparation does not include administering an injection.
Report units based on doses prepared, not shots given. For Medicare, one dose is a 1 mL aliquot from a multidose vial, regardless of the volume injected at a visit; a 10 mL vial therefore supports 10 units. The record should identify each vial's allergens, concentration, volume, preparation date, and supervising physician. When administered, injections are reported separately with 95115 for one injection or 95117 for two or more. CMS assigns substantially more practice-expense RVUs to this service in the office than in a facility.
Where the value comes from
- Work RVU0.06 · 12%
- Practice expense (office) RVU0.45 · 87%
- Malpractice RVU0.01 · 2%
5.9M
Medicare services in 2024 · #37 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
95165 compared with similar codes
Office rates for Missouri, from the same CMS release.
$54.15–$59.57
95146 covers preparation of two stinging-insect venoms. 95165 covers multidose extracts for non-venom allergens, such as pollens or dust mites.
$10.69–$11.78
95117 reports administering two or more allergy shots at a visit. 95165 reports preparation of the extract, whether or not an injection occurs that day.
95125
No office rateImmunotherapy 2/> injections
95125 combines extract provision with two or more injections and is not recognized by Medicare. When both services are furnished for non-venom immunotherapy, report the appropriate 95117 and 95165 units separately.
Compare 95165 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
3 of 3 payment localities
Metropolitan Kansas City →
Office / nonfacility
$16.44
Facility
$2.64
Metropolitan St. Louis →
Office / nonfacility
$16.65
Facility
$2.66
Rest Of Missouri →
Office / nonfacility
$15.29
Facility
$2.62
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95165 billing questions
How many units should be billed for a multidose vial?
Medicare counts one unit per 1 mL aliquot from the vial: a 5 mL vial supports 5 units, and a 10 mL vial supports 10. The volume injected at each visit does not change that count.
Can 95165 be billed on the same day as an injection code?
Yes, when extract preparation and administration both occur that day. Report preparation with 95165 and administration with 95115 for one injection or 95117 for two or more.
What if the allergist prepares the extract but another physician gives the shots?
The preparing practice reports 95165 for the doses prepared. The administering practice reports 95115 or 95117 for injections it gives, rather than reporting 95165 for extract it did not prepare.
Should the complete-service codes 95120 through 95134 be used for Medicare patients?
No. Medicare does not recognize those combined injection-and-extract codes. Report the appropriate injection and antigen preparation codes separately when both services are furnished.
When is 95144 used instead of 95165?
Use 95144 for extract prepared in single-dose vials. Use 95165 for extract prepared in multidose vials, with units based on the doses the vials contain.
Can an E/M visit be billed on an injection day?
A separately identifiable evaluation of new symptoms may be reported when it goes beyond routine injection screening and is documented. Append modifier 25 to the E/M code.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
12,48495147,,Antigen therapy services,A,,0.06,1.73,,0.01,,0.01,1.80,0.08,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
12,48595148,,Antigen therapy services,A,,0.06,2.60,,0.01,,0.01,2.67,0.08,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
12,48695149,,Antigen therapy services,A,,0.06,3.48,,0.01,,0.01,3.55,0.08,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
12,48795165,,Antigen therapy services,A,,0.06,0.45,,0.01,,0.01,0.52,0.08,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
12,48895170,,Antigen therapy services,A,,0.06,0.25,,0.01,,0.01,0.32,0.08,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
12,48995180,,Rapid desensitization,A,,2.01,2.04,,0.52,,0.07,4.12,2.60,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
12,49095199,,Unlisted all/immlg svc/px,C,,0.00,0.00,,0.00,,0.00,0.00,0.00,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00