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CMS RVU26D · Effective 2026-10-01

96422 Arterial infusion Medicare reimbursement rates in Missouri

Reports antineoplastic medication infused into an artery during the initial hour, such as regional chemotherapy delivered through an arterial catheter. Compare 96422 office and facility rates across CMS payment localities in Missouri.

Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.

What does Medicare pay for 96422 in Missouri?

Missouri has 3 payment localities in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the 3 payment areas shown below, using the same CMS release.

Office / nonfacility

$121.97–$133.94

3 of 3 localities have a supported rate.

Lowest: Rest Of Missouri

Highest: Metropolitan St. Louis

A spread of $11.97 per service.

Facility setting

No supported rate

These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.

Find 96422 in your payment locality →

Where 96422 pays more and less in Missouri

3 payment localities

$121.97 to $133.94

$121.97$127.95$133.94
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

Chemotherapy administration

About 96422: Intra-arterial chemotherapy infusion, initial hour

Reports antineoplastic medication infused into an artery during the initial hour, such as regional chemotherapy delivered through an arterial catheter.

Code 96422 represents chemotherapy delivered by infusion into an artery. Oncology clinicians may use this approach for regional treatment, such as delivering chemotherapy through a catheter positioned in the hepatic artery for liver-directed therapy. The code concerns the medication administration, not placement of the arterial catheter. It is distinct from an arterial injection and from infusion through a vein.

Select this code when the antineoplastic agent is infused intra-arterially and the administration fits the code’s first-hour scope. The medication may be reported separately when applicable; consider 96423 for qualifying additional infusion time. Document the agent, arterial route, and infusion start and stop times in the treatment record. Under the CMS incident-to rule supplied for this code, Medicare billing requires that the service be performed under physician supervision.

CMS billing rules for 96422

Professional and technical components
Incident-to service: billed only when performed under physician supervision.

Where the value comes from

  • Work RVU0.17 · 4%
  • Practice expense (office) RVU3.96 · 94%
  • Malpractice RVU0.07 · 2%

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

96422 compared with similar codes

Office rates for Missouri, from the same CMS release.

96420

Chemotherapy push

Intra-arterial route

$91.70–$100.54

Both involve intra-arterial chemotherapy, but 96420 is for push administration; 96422 is for infusion.

96423

Chemotherapy infusion

Intra-arterial, each additional hour

$66.04–$72.22

96422 covers the initial infusion period. Code 96423 is used for qualifying additional intra-arterial infusion time.

96413

Chemo IV infusion

Initial drug, first hour

$116.43–$127.44

96413 describes chemotherapy infusion through a vein; 96422 is for delivery into an artery.

Compare 96422 by payment locality

Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.

3 of 3 payment localities

Office and facility base rates · shared scale starting at $0

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96422 billing questions

When is 96422 used instead of 96420?

Use 96422 for chemotherapy administered by intra-arterial infusion. Code 96420 describes intra-arterial delivery by push technique.

Can the chemotherapy drug be billed separately?

The administration code reports the infusion service, not the medication supply. Report the drug separately when applicable.

When might 96423 be reported with 96422?

Code 96423 is the additional-hour code for intra-arterial chemotherapy infusion. The documented infusion duration must support reporting additional time.

What documentation supports 96422?

Record the antineoplastic agent, intra-arterial route, and infusion start and stop times in the treatment record.

What supervision is required for Medicare billing?

Under the CMS incident-to rule for this code, the service must be performed under physician supervision for Medicare billing.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.

Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.

RVUs for 96422PPRRVU2026_Oct_nonQPP.csv, line 12,806 (RVU26D)
Open CMS sourceHow this rate is calculatedBuild a fee sheet