Use 25066 for a deep soft-tissue biopsy in the forearm or wrist; use 25065 when the biopsy target is superficial.
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CMS RVU26D · Effective 2026-10-01
25066 Soft-tissue biopsy Medicare reimbursement rates in Nebraska
Report this service when a surgeon obtains a tissue sample from a deep soft-tissue mass in the forearm or wrist for diagnostic evaluation. Compare 25066 office and facility rates across CMS payment localities in Nebraska.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 25066 in Nebraska?
Nebraska has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
No supported rate
Facility setting
$326.57
1 of 1 localities have a supported rate.
Payment area: Nebraska
One mapped payment locality.
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Orthopedic surgery
About 25066: Deep forearm soft-tissue biopsy
Report this service when a surgeon obtains a tissue sample from a deep soft-tissue mass in the forearm or wrist for diagnostic evaluation.
This service covers obtaining a diagnostic tissue sample from a deep soft-tissue mass in the forearm or wrist, rather than removing the entire lesion. An orthopedic or hand surgeon commonly performs the biopsy in an operating room when the target lies beneath superficial tissues and requires operative exposure. The sample may be submitted for pathologic examination; the biopsy code describes the surgeon’s tissue-sampling procedure, not the pathologist’s interpretation.
Choose this code when the operative report supports a deep biopsy and describes the target, its location, the approach, and the tissue obtained. A superficial biopsy belongs to the related lower-level code; complete lesion removal is coded by the applicable excision code instead. CMS assigns a 90-day global period, including the day-before preoperative visit and related postoperative care for 90 days. When multiple procedures occur in one session, the highest-valued procedure is paid in full and others at 50%. For bilateral procedures reported with modifier 50, payment is 150%. Medicare does not pay an assistant at surgery; co-surgeons and team surgery are not permitted.
CMS billing rules for 25066
- Global period
- Major surgery with a 90-day global period: the day-before preoperative visit and 90 days of related postoperative care are included.
- Multiple procedures
- Standard multiple procedure reduction: the highest-valued procedure is paid in full and others at 50% when performed in the same session.
- Bilateral procedures
- Bilateral procedure with modifier 50 is paid at 150%.
- Assistant at surgery
- Statutory restriction: assistant at surgery is not paid.
- Co-surgeons
- Co-surgeons not permitted.
- Team surgery
- Team surgery not permitted.
Where the value comes from
- Work RVU4.16 · 39%
- Practice expense (office) RVU5.75 · 54%
- Malpractice RVU0.82 · 8%
1.1K
Medicare services in 2024 · #2886 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
25066 compared with similar codes
Office rates for Nebraska, from the same CMS release.
Use 25066 when the surgeon obtains a diagnostic tissue sample. Use 25076 when a deep lesion under 3 cm is excised.
Use 25066 for sampling a deep lesion. Use 25073 when the deep lesion is excised and measures 3 cm or larger.
Compare 25066 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Nebraska →
Office / nonfacility
Unavailable
Facility
$326.57
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 25066 in Nebraska.
PPRRVU2026_Oct_nonQPP.csv
2,379
- Code
- 25066
- Physician work
- 4.16
- Practice expense
- 5.75
- Malpractice
- 0.82
GPCI2026.csv
72
- Locality
- Nebraska
- Physician work
- 1.000
- Practice expense
- 0.923
- Malpractice
- 0.378
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 4.16 | × 1.000 | 4.1600 |
| Practice expense | 5.75 | × 0.923 | 5.3072 |
| Malpractice | 0.82 | × 0.378 | 0.3100 |
| Total RVUs | 9.7772 | ||
| Conversion factor | × 33.4009 | ||
Facility rate, Nebraska$326.57
Explore RVUs, geographic factors and the full formula
Facility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 4.16 | 1 |
| Practice expense | 5.75 | 0.923 |
| Malpractice | 0.82 | 0.378 |
(4.16 × 1 + 5.75 × 0.923 + 0.82 × 0.378) × $33.4009 = $326.57
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
25066 billing questions
How does this differ from 25065?
This code is for biopsy of deep forearm or wrist soft tissue. Code 25065 is for a superficial biopsy.
Can the surgeon report this when the whole mass is removed?
No. This code represents obtaining a diagnostic sample, not complete lesion removal. Select the applicable excision code when the operative service removes the lesion.
What documentation supports the deep-tissue selection?
Document the mass location and depth, the operative exposure or approach, and the tissue sampled. The record should make clear that the target was deep rather than superficial.
How is bilateral biopsy handled?
CMS identifies this as a bilateral procedure. When both sides are treated and modifier 50 is reported, payment is 150%.
Does the biopsy code include pathology interpretation?
The code describes the surgeon’s tissue-sampling procedure. A pathologist’s examination and interpretation of the submitted specimen are a separate professional service when performed and appropriately reported.
What global-period services are included?
The 90-day global period includes the day-before preoperative visit and related postoperative care during the following 90 days.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
