Both apply to urinary tract specimen FISH with three to five probes. The distinction is computer-assisted analysis under 88121 versus the method represented by 88120.
On this page
CMS RVU26D · Effective 2026-10-01
88120 Urine FISH Medicare reimbursement rates in Nebraska
Reports FISH analysis of a urinary tract specimen using three to five molecular probes, commonly to assess for urothelial carcinoma-associated chromosomal changes. Compare 88120 office and facility rates across CMS payment localities in Nebraska.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 88120 in Nebraska?
Nebraska has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$502.45
1 of 1 localities have a supported rate.
Payment area: Nebraska
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Cytopathology
About 88120: Urinary tract FISH, three to five probes
Reports FISH analysis of a urinary tract specimen using three to five molecular probes, commonly to assess for urothelial carcinoma-associated chromosomal changes.
This service uses fluorescent in situ hybridization to assess cells in a urinary tract specimen for chromosomal changes associated with urothelial carcinoma. It is commonly used in the evaluation or surveillance of patients with a history of bladder cancer, including when urine testing is used to look for evidence of recurrent disease. Laboratory personnel prepare and process the specimen; a pathologist interprets the findings. The code represents analysis with three to five probes for each specimen, rather than conventional microscopic urine cytology.
Report one unit for each specimen analyzed under the three-to-five-probe method. Documentation should identify the specimen, the FISH analysis performed, the probes or probe set used, and the interpreted result. CMS recognizes professional and technical components: modifier 26 identifies the interpretation, and modifier TC identifies the equipment and staff work. Report without either modifier when billing the global service, which includes both components.
CMS billing rules for 88120
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU1.17 · 7%
- Practice expense (office) RVU15.01 · 92%
- Malpractice RVU0.05 · 0%
55K
Medicare services in 2024 · #749 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
88120 compared with similar codes
Office rates for Nebraska, from the same CMS release.
88112 reports cell-enhanced cytopathology preparation and examination. 88120 reports FISH probe analysis for chromosomal changes, not cell morphology alone.
88108 is for cytopathology of a concentrated fluid specimen. 88120 is selected for urinary tract specimen FISH using three to five molecular probes.
Compare 88120 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Nebraska →
Office / nonfacility
$502.45
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 88120 in Nebraska.
PPRRVU2026_Oct_nonQPP.csv
11,115
- Code
- 88120
- Physician work
- 1.17
- Practice expense
- 15.01
- Malpractice
- 0.05
GPCI2026.csv
72
- Locality
- Nebraska
- Physician work
- 1.000
- Practice expense
- 0.923
- Malpractice
- 0.378
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 1.17 | × 1.000 | 1.1700 |
| Practice expense | 15.01 | × 0.923 | 13.8542 |
| Malpractice | 0.05 | × 0.378 | 0.0189 |
| Total RVUs | 15.0431 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Nebraska$502.45
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 1.17 | 1 |
| Practice expense | 15.01 | 0.923 |
| Malpractice | 0.05 | 0.378 |
(1.17 × 1 + 15.01 × 0.923 + 0.05 × 0.378) × $33.4009 = $502.45
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
88120 billing questions
How does 88120 differ from 88121?
Both describe urinary tract specimen FISH using three to five probes. 88121 is the related code for analysis using computer-assisted technology; select the code that matches the method documented.
Is this conventional urine cytology?
No. This code is for fluorescent in situ hybridization to detect chromosomal changes. Conventional cytology evaluates cell appearance and is reported with a different cytopathology code.
How many units are reported?
Report per specimen analyzed with the three-to-five-probe method. The probe count does not create a separate unit for each probe.
When should modifier 26 or TC be used?
Use modifier 26 for the professional interpretation alone and modifier TC for the technical work alone. An unmodified claim represents the global service, including both components.
What documentation supports the service?
Record the urinary tract specimen, the FISH method and probe set, the analysis performed, and the interpreted findings. The documentation should support that three to five probes were used for each specimen.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
