81455
No office rateSo/hl 51/>gsap dna/dna&rna
81455 identifies a targeted genomic sequencing panel for specified neoplasm types; G0452 reports the physician’s interpretation and report of molecular results.
On this page
CMS RVU26D · Effective 2026-10-01
G0452 Molecular interpretation Medicare reimbursement rates in Oklahoma
Reports a physician’s interpretation of molecular pathology test results, separately from or as part of the global diagnostic service. Compare G0452 office and facility rates across CMS payment localities in Oklahoma.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for G0452 in Oklahoma?
Oklahoma has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$44.93
1 of 1 localities have a supported rate.
Payment area: Oklahoma
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Molecular pathology
About G0452: Molecular pathology interpretation and report
Reports a physician’s interpretation of molecular pathology test results, separately from or as part of the global diagnostic service.
A physician reviews results from a molecular pathology assay and prepares an interpretation and report. The testing may analyze DNA or RNA from sources such as tumor tissue or blood to identify molecular findings relevant to diagnosis or treatment. A pathologist or another qualified physician may provide this service in a hospital, reference laboratory, or other setting where molecular diagnostic testing is performed.
Report G0452 for the physician’s interpretive service when supported by the work documented; the assay itself is represented by its applicable test code. CMS recognizes professional and technical components: modifier 26 identifies the interpretation, and modifier TC identifies the technical work, including equipment and staff. Without either modifier, the claim represents the global service. Documentation should identify the test results reviewed and include the physician’s interpretive findings and report. The CMS file lists modifiers 26 and TC as separately priced.
CMS billing rules for G0452
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU0.91 · 65%
- Practice expense (office) RVU0.47 · 34%
- Malpractice RVU0.02 · 1%
163.3K
Medicare services in 2024 · #428 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
G0452 compared with similar codes
Office rates for Oklahoma, from the same CMS release.
81479
No office rateUnlisted molecular pathology
81479 represents an unlisted molecular pathology procedure when the assay lacks a specific code. G0452 represents interpretive work, not the assay procedure.
81450
No office rateHl neo gsap 5-50dna/dna&rna
81450 identifies genomic sequencing for hematolymphoid neoplasms. G0452 describes the physician’s interpretation and report rather than the sequencing assay.
Compare G0452 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Oklahoma →
Office / nonfacility
$44.93
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for G0452 in Oklahoma.
PPRRVU2026_Oct_nonQPP.csv
15,270
- Code
- G0452
- Physician work
- 0.91
- Practice expense
- 0.47
- Malpractice
- 0.02
GPCI2026.csv
86
- Locality
- Oklahoma
- Physician work
- 1.000
- Practice expense
- 0.893
- Malpractice
- 0.777
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.91 | × 1.000 | 0.9100 |
| Practice expense | 0.47 | × 0.893 | 0.4197 |
| Malpractice | 0.02 | × 0.777 | 0.0155 |
| Total RVUs | 1.3453 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Oklahoma$44.93
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0.91 | 1 |
| Practice expense | 0.47 | 0.893 |
| Malpractice | 0.02 | 0.777 |
(0.91 × 1 + 0.47 × 0.893 + 0.02 × 0.777) × $33.4009 = $44.93
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
G0452 billing questions
When should G0452 be reported instead of the molecular assay code?
G0452 represents the physician’s interpretation and report, not the laboratory procedure that generates the molecular results. Report the applicable assay code for the testing itself.
How do modifiers 26 and TC affect G0452?
Modifier 26 reports the professional interpretation, while modifier TC reports the technical work, including equipment and staff. Without a modifier, G0452 represents the global service.
What documentation supports G0452?
Document the molecular test results reviewed and the physician’s interpretation and report. The record should make clear that the reported service includes interpretive work, not only test performance.
Can G0452 be reported with a molecular assay code?
Yes, the interpretation may be reported with the applicable molecular assay code when both the test and the physician’s interpretive service are furnished and documented.
Does G0452 describe a particular gene panel or specimen?
No. G0452 identifies the interpretation and report service; the assay code identifies the specific molecular test and its scope.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
15,267G0447,,Behavior counsel obesity 15m,A,,0.60,0.38,,0.15,,0.04,1.02,0.79,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
15,268G0448,,Place perm pacing cardiovert,E,,0.00,0.00,,0.00,,0.00,0.00,0.00,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
15,269G0451,,Devlopment test interpt&rep,A,,0.00,0.36,,0.36,NA,0.01,0.37,0.37,5,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,04,0,99,0.00,0.00,0.00
15,270G0452,,Molecular pathology interpr,A,,0.91,0.47,,0.47,NA,0.02,1.40,1.40,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
15,271G0452,26,Molecular pathology interpr,A,,0.91,0.39,,0.39,,0.01,1.31,1.31,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
15,272G0452,TC,Molecular pathology interpr,A,,0.00,0.08,,0.08,NA,0.01,0.09,0.09,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
15,273G0453,,Cont intraop neuro monitor,A,,0.60,0.17,NA,0.17,,0.05,0.82,0.82,0,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
8311502,NC,00,NORTH CAROLINA,1.000,0.933,0.639
8403302,ND,01,NORTH DAKOTA**,1.000,1.000,0.406
8515202,OH,00,OHIO,1.000,0.913,1.008
8604312,OK,00,OKLAHOMA,1.000,0.893,0.777
8702302,OR,01,PORTLAND,1.016,1.111,0.744
8802302,OR,99,REST OF OREGON,1.000,0.996,0.703
8912502,PA,01,METROPOLITAN PHILADELPHIA,1.018,1.041,1.193