$148.84
15271 reports the application procedure for qualifying trunk and extremity wounds; Q4101 reports the Apligraf product used with that procedure.
On this page
CMS RVU26D · Effective 2026-10-01
Q4101 Skin substitute Medicare reimbursement rates in Wisconsin
Q4101 reports Apligraf supplied for wound treatment, measured by area and billed with the procedure used to apply the product. Compare Q4101 office and facility rates across CMS payment localities in Wisconsin.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4101 in Wisconsin?
Wisconsin has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$121.91
1 of 1 localities have a supported rate.
Payment area: Wisconsin
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Wound care
About Q4101: Apligraf skin substitute supply
Q4101 reports Apligraf supplied for wound treatment, measured by area and billed with the procedure used to apply the product.
Q4101 represents Apligraf, a living skin substitute used to support healing of chronic wounds such as venous leg ulcers and diabetic foot ulcers. Wound-care physicians, surgeons, podiatrists, and other clinicians may apply it in outpatient wound clinics or other settings where these wounds are treated. The code represents the product, not the clinician’s application service.
Report the quantity based on the square centimeters of Apligraf supplied, and document the wound, product used, and amount applied. Q4101 is an add-on code: report it only with a primary application procedure, and its payment falls within that procedure’s global period. CMS assigns no physician work RVUs and assigns practice-expense RVUs. CMS classifies Q4101 as technical-component-only; a separate code covers interpretation.
CMS billing rules for Q4101
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4101 compared with similar codes
Office rates for Wisconsin, from the same CMS release.
$151.75
15275 reports the application procedure for qualifying wounds at specified sites such as the head, neck, hands, feet, or genitalia; Q4101 reports the product.
$121.91
Q4102 identifies Oasis wound matrix, not Apligraf. Select the product code that matches the skin substitute supplied.
Compare Q4101 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Wisconsin →
Office / nonfacility
$121.91
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for Q4101 in Wisconsin.
PPRRVU2026_Oct_nonQPP.csv
18,201
- Code
- Q4101
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
111
- Locality
- Wisconsin
- Physician work
- 1.000
- Practice expense
- 0.958
- Malpractice
- 0.308
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.000 | 0.0000 |
| Practice expense | 3.81 | × 0.958 | 3.6500 |
| Malpractice | 0.00 | × 0.308 | 0.0000 |
| Total RVUs | 3.6500 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Wisconsin$121.91
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0 | 1 |
| Practice expense | 3.81 | 0.958 |
| Malpractice | 0 | 0.308 |
(0 × 1 + 3.81 × 0.958 + 0 × 0.308) × $33.4009 = $121.91
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
Q4101 billing questions
Does Q4101 report the Apligraf application?
No. Q4101 reports the Apligraf product; report the applicable skin-substitute application procedure separately as the primary service.
What is the unit of service?
Q4101 is measured per square centimeter. Document the wound area treated and the amount of Apligraf used.
Can Q4101 be billed by itself?
No. It is an add-on code and must be reported with a primary procedure, such as the applicable skin-substitute application code.
How does the global-period rule affect payment?
Q4101 is paid within the primary procedure’s global period. Its payment is tied to that procedure rather than treated as a separate standalone service.
Does Q4101 include an interpretation?
No. CMS classifies Q4101 as technical-component-only, and a separate code covers interpretation.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,198Q4074,,Iloprost non-comp unit dose,E,,0.00,0.00,,0.00,,0.00,0.00,0.00,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
18,199Q4081,,"Epoetin alfa, 100 units esrd",E,,0.00,0.00,,0.00,,0.00,0.00,0.00,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
18,200Q4082,,Drug/bio noc part b drug cap,E,,0.00,0.00,,0.00,,0.00,0.00,0.00,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
18,201Q4101,,Apligraf,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,202Q4102,,Oasis wound matrix,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,203Q4103,,Oasis burn matrix,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,204Q4104,,Integra bmwd,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
10802402,WA,02,SEATTLE (KING CNTY),1.050,1.227,0.817
10902402,WA,99,REST OF WASHINGTON,1.013,1.053,0.761
11011402,WV,16,WEST VIRGINIA,1.000,0.869,1.431
11106302,WI,00,WISCONSIN,1.000,0.958,0.308
11203602,WY,21,WYOMING**,1.000,1.000,0.740
113"MAC Assignments as of November 22, 2023",,,,,,
114,,,,,,