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CMS RVU26D · Effective 2026-10-01

33221 Pacemaker generator Medicare reimbursement rates in Wyoming

Insertion of a pulse generator connected to an existing multiple-lead pacemaker system, typically when the leads remain in place and only the generator is implanted. Compare 33221 office and facility rates across CMS payment localities in Wyoming.

Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.

What does Medicare pay for 33221 in Wyoming?

Wyoming has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.

Office / nonfacility

No supported rate

Facility setting

$307.44

1 of 1 localities have a supported rate.

Payment area: Wyoming**

One mapped payment locality.

These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.

Find 33221 in your payment locality →

Cardiology procedure

About 33221: Multiple-lead pacemaker generator insertion

Insertion of a pulse generator connected to an existing multiple-lead pacemaker system, typically when the leads remain in place and only the generator is implanted.

Code 33221 describes placing a pacemaker pulse generator and connecting it to an existing multiple-lead pacing system. Electrophysiologists and other qualified cardiac surgeons commonly perform the procedure in a hospital operating room or electrophysiology setting. A typical clinical context is a multilead system, such as cardiac resynchronization pacing, whose leads are already in place and will be connected to the new generator.

Report 33221 when the procedure is limited to generator insertion with existing multiple leads; documentation should identify the existing leads and describe generator placement and connection. When the generator is removed and replaced, consider the replacement code for a multiple-lead system instead. CMS assigns a 90-day global period, including the day-before preoperative visit and 90 days of related postoperative care. For multiple procedures in one session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Modifier 50 is inappropriate. Assistant-at-surgery payment is statutorily restricted, and co-surgeons and team surgery are not permitted.

CMS billing rules for 33221

Global period
Major surgery with a 90-day global period: the day-before preoperative visit and 90 days of related postoperative care are included.
Multiple procedures
Standard multiple procedure reduction: the highest-valued procedure is paid in full and others at 50% when performed in the same session.
Bilateral procedures
Bilateral adjustment does not apply; the descriptor or anatomy makes modifier 50 inappropriate.
Assistant at surgery
Statutory restriction: assistant at surgery is not paid.
Co-surgeons
Co-surgeons not permitted.
Team surgery
Team surgery not permitted.

Where the value comes from

  • Work RVU5.41 · 57%
  • Practice expense (office) RVU2.84 · 30%
  • Malpractice RVU1.29 · 14%

167

Medicare services in 2024 · #4485 by national volume

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

33221 compared with similar codes

Office rates for Wyoming, from the same CMS release.

33213

Pacemaker generator

Existing dual leads

No office rate

Choose 33213 for generator insertion with an existing dual-lead system. Use 33221 when the existing pacing system has multiple leads.

33229

Pacemaker replacement

Multiple lead system

No office rate

33229 describes removing and replacing a generator in a multiple-lead system. Code 33221 is for generator insertion without that removal-and-replacement service.

33208

Pacemaker implant

Atrial and ventricular leads

No office rate

33208 describes implantation of a new atrial-and-ventricular pacing system. Code 33221 applies when multiple leads are already present and the service is generator insertion.

Compare 33221 by payment locality

Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.

1 of 1 payment localities

Office and facility base rates · shared scale starting at $0

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How this local rate is calculated

Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 33221 in Wyoming**.

PPRRVU2026_Oct_nonQPP.csv

3,850

Code
33221
Physician work
5.41
Practice expense
2.84
Malpractice
1.29

GPCI2026.csv

112

Locality
Wyoming**
Physician work
1.000
Practice expense
1.000
Malpractice
0.740
Facility calculation for 33221 in Wyoming**
ComponentRVULocality factorAdjusted
Physician work5.41× 1.0005.4100
Practice expense2.84× 1.0002.8400
Malpractice1.29× 0.7400.9546
Total RVUs9.2046
Conversion factor× 33.4009

Facility rate, Wyoming**$307.44

Explore RVUs, geographic factors and the full formula

Facility

Facility calculation inputs
ComponentRVULocal GPCI
Work5.411
Practice expense2.841
Malpractice1.290.74

(5.41 × 1 + 2.84 × 1 + 1.29 × 0.74) × $33.4009 = $307.44

The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.

33221 billing questions

How is 33221 different from 33213?

33221 is for a generator connected to an existing multiple-lead system. Code 33213 is the generator-only choice for an existing dual-lead system.

Should 33221 be used when the generator is replaced?

Use the multiple-lead generator removal-and-replacement code, 33229, when the existing generator is removed and replaced. Code 33221 describes generator insertion rather than removal and replacement.

Does 33221 include placement of new leads?

It describes generator insertion with multiple leads already in place, not placement of new leads. The operative report should establish whether the leads were existing or newly implanted.

Can modifier 50 be reported?

No. CMS identifies bilateral adjustment as inappropriate for this code.

How does the 90-day global period affect postoperative billing?

The day-before preoperative visit and 90 days of related postoperative care are included in the global period.

How are other same-session procedures paid?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and other procedures are paid at 50%. Assistant-at-surgery payment is statutorily restricted; co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.

Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.

RVUs for 33221PPRRVU2026_Oct_nonQPP.csv, line 3,850 (RVU26D)
Geographic factors for Wyoming**GPCI2026.csv, line 112 (RVU26D)