CPT code 0207U: Alzheimer assay, phosphorylated ERK imaging2026 Medicare lab fee · Clinical Laboratory Fee Schedule
This test quantifies phosphorylated ERK1 and ERK2 responses in cultured skin fibroblasts and reports an Alzheimer disease probability index.
Medicare pays $511.20 for 0207U under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$511.20
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2022
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 0207U covers
0207U covers quantitative in-situ immunofluorescence imaging of phosphorylated ERK1 and ERK2 in cultured skin fibroblasts after bradykinin stimulation. The result is expressed as a probability index for Alzheimer disease. A laboratory cultures fibroblasts from a skin specimen and performs the assay; the result may be used in an Alzheimer disease evaluation. The test measures the response of cultured cells to bradykinin treatment.
Report 0207U as an add-on code in addition to the primary procedure. Medicare pays 0207U under the CLFS only, using one national amount across localities with no office-versus-facility adjustment. The 2026 national CLFS amount is $511.20, unchanged from 2022 through 2026. The code has no physician fee schedule payment row.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 0207U
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 0207U. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Not on the physician fee schedule
The physician fee schedule doesn’t list 0207U: Medicare pays the test only from the CLFS.
0207U on the lab fee schedule since 2020
0207U · CLFS 2026 Q4 (current)
$511.20
Unchanged since Jan 1, 2022
Every change on file
- Jan 1, 2022 · CLFS 2022 Q1MAC-priced → $511.20
25 quarterly CLFS releases on file, first CLFS 2020 Q4. A code missing from a quarter wasn’t on that release.
0207U compared with similar tests
- 0206UAlzheimer cell testCultured skin fibroblasts$2,215.40
- 0206U identifies an Alzheimer-related cell-aggregation analysis. 0207U quantifies phosphorylated ERK1 and ERK2 in bradykinin-treated cultured skin fibroblasts.
0207U billing questions
Can 0207U be reported by itself?
0207U is designated as an add-on code and is reported in addition to a primary procedure.
How does 0207U differ from 0206U?
0207U quantifies the phosphorylated ERK1 and ERK2 response after bradykinin treatment. 0206U identifies an Alzheimer-related cell-aggregation analysis.
What specimen is used for 0207U?
The test uses cultured skin fibroblasts derived from a skin specimen.
How does Medicare pay for 0207U?
Medicare pays 0207U under the CLFS using one national amount across localities, without an office-versus-facility adjustment.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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