CPT code 0210U: RPR test, quantitative immunoassay2026 Medicare lab fee · Clinical Laboratory Fee Schedule
A quantitative immunoassay measures nontreponemal antibodies associated with syphilis, supporting evaluation and follow-up of patients tested with an RPR assay.
Medicare pays $18.63 for 0210U under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$18.63
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2021
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 0210U covers
This assay measures nontreponemal antibodies associated with syphilis and reports a quantitative RPR result. Clinicians may order it when evaluating suspected syphilis or following antibody levels during patient management. Clinical laboratories perform and report the test; it is distinct from testing for treponemal-specific antibodies. The result is interpreted with the patient’s clinical history and other syphilis test results.
Report 0210U for the quantitative immunoassay performed. It is paid through the Medicare Clinical Laboratory Fee Schedule, with one national amount applying across states and localities and no office or facility payment difference. The 2026 national CLFS amount is $18.63, unchanged each year from 2021 through 2026. Medicare pays this code through the CLFS.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 0210U
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 0210U. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Not on the physician fee schedule
The physician fee schedule doesn’t list 0210U: Medicare pays the test only from the CLFS.
0210U on the lab fee schedule since 2020
0210U · CLFS 2026 Q4 (current)
$18.63
Unchanged since Jan 1, 2021
Every change on file
- Jan 1, 2021 · CLFS 2021 Q1MAC-priced → $18.63
25 quarterly CLFS releases on file, first CLFS 2020 Q4. A code missing from a quarter wasn’t on that release.
0210U compared with similar tests
- 86592Syphilis testQualitative, nontreponemal$4.27
- 86592 is for qualitative nontreponemal antibody testing. Use 0210U for the quantitative RPR immunoassay when that is the test performed.
- 86593Syphilis testQuantitative antibody test$4.40
- 86593 is the conventional quantitative nontreponemal test code. 0210U identifies a quantitative immunoassay; select the code that describes the actual assay performed.
- 86780Syphilis antibodyTreponemal antibody$13.24
- 86780 measures treponemal antibodies, whereas 0210U measures nontreponemal antibodies associated with syphilis. They are different tests and may be used together in an evaluation.
0210U billing questions
When should 0210U be reported instead of 86592?
0210U describes a quantitative RPR immunoassay. CPT 86592 is the qualitative nontreponemal antibody test, so choose according to the test performed and result reported.
How does 0210U differ from 86593?
Both relate to quantitative nontreponemal antibody testing. Report the code that matches the assay performed; 0210U identifies the quantitative immunoassay, while 86593 is the conventional quantitative test code.
Is 0210U a treponemal antibody test?
No. It measures nontreponemal antibodies associated with syphilis. Treponemal antibody testing, such as 86780, measures a different antibody response.
Does Medicare pay 0210U under the physician fee schedule?
No. Medicare pays 0210U through the CLFS.
Does the CLFS payment vary by locality or setting?
No. The code has one national CLFS amount across states and localities, with no office or facility payment difference.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
Fee sheets · Coming soon
Put 0210U and the rest of your codes on one sheet
Your codes at your locality, with payer contracts beside Medicare.
Join the waitlist