CPT code 21558: Tumor resection, neck/anterior thorax, 5 cm or larger2026 Medicare rate & RVUs in Maryland

Radical resection of a soft-tissue tumor in the neck or anterior thorax measuring at least 5 cm, typically for definitive oncologic treatment.

CMS RVU26DEffective Oct 1, 20263 payment localities650 Medicare services in 2024

CMS doesn’t publish an office rate for 21558 in Maryland.

—Office (non-facility)
$1,220.59–$1,341.98Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Maryland
  2. What 21558 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 21558 covers

This service covers radical removal of a soft-tissue tumor, such as a sarcoma, in the neck or anterior thorax when the tumor is at least 5 cm. It represents a more extensive oncologic resection than a limited excision or diagnostic biopsy. Head and neck or surgical oncology surgeons commonly perform it in an operating room, with the operative approach and extent guided by the tumor’s location and treatment plan.

Report the code when the operative record supports radical resection and identifies the anatomic site, tumor size, and extent of removal. The service has a 90-day global period, including the day-before preoperative visit and related postoperative care during that period. For other procedures performed in the same session, the highest-valued procedure is paid in full and additional procedures are subject to the standard 50% multiple procedure reduction. An assistant at surgery may be paid; co-surgeons require supporting documentation, and team surgery is not permitted. Modifier 50 is inappropriate for this code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 21558 pays more and less in Maryland

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

21558 office and facility rates by payment locality
Payment localityOfficeFacility
Baltimore area, MDUnavailable$1,295.23
Rest of MarylandUnavailable$1,220.59
Washington, DC areaUnavailable$1,341.98

How the 21558 rate is calculated

Each of 21558’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 21558

RVUs × geographic indexes × conversion factor

Office or facility?

Work21.04

21.04 RVUs× 1.000 GPCI

Practice expense11.03

11.03 RVUs× 1.000 GPCI

Malpractice4.50

4.50 RVUs× 1.000 GPCI

Adjusted RVUs

36.5700

Conversion factor

$33.4009

Medicare rate

$1,221.47

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 21558

21558 has a 90-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 21558

Tumor resection, neck/anterior thorax, 5 cm or larger

RuleCMS valueWhat it means
Global period090Major surgery: the day before, the day of, and 90 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)2Paid.
Co-surgeons (62)1Permitted with supporting documentation.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.69/0.21Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 21558

Tumor resection, neck/anterior thorax, 5 cm or larger

90-day global period ends

Dec 30, 2026

Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).

Visit on Oct 31, 2026

Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.

  • 24Unrelated E/M visit by the same physician
  • 79Unrelated procedure (starts its own global period)
  • 58Staged, more extensive, or therapy procedure that was planned
  • 78Unplanned return to the operating room for a related complication
SurgeryVisit
Sep 23, 2026Jan 10, 2027

Pre-op dayGlobal period

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

21558 without 51 · national facility

$1,221.47

Tumor resection, neck/anterior thorax, 5 cm or larger

21558-51 · Second procedure: 50%

$610.74

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

21558 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 21558

    Tumor resection, neck/anterior thorax, 5 cm or larger21.04 wRVU

    Not priced

  • 21557

    Tumor resection, radical, under 5 cm14.38 wRVU

    Not priced

  • 21554

    Tumor excision, deep, 5 cm or larger10.85 wRVU

    Not priced

  • 21550

    Soft-tissue biopsy, deep neck or thorax2.06 wRVU

    $271.88

How to choose

21557Tumor resectionRadical, under 5 cm
Both describe radical resection in the neck or anterior thorax; 21557 is for tumors under 5 cm, while 21558 is for tumors 5 cm or larger.
21554Tumor excisionDeep, 5 cm or larger
Use 21554 for a deep neck tumor at least 5 cm when the documented procedure is an excision, rather than the radical resection represented by 21558.
21550Soft-tissue biopsyDeep neck or thorax
21550 describes biopsy of a neck or chest lesion. It is for diagnostic tissue sampling, not definitive radical tumor resection.

21558 billing questions

How is 21558 different from 21554?

Both concern a deep neck tumor at least 5 cm, but 21558 is for radical resection. Use 21554 for the applicable deep-tumor excision when the documented operation is not a radical resection.

Does the tumor need to measure at least 5 cm?

Yes. This code is for a tumor measuring 5 cm or larger; 21557 is the related radical-resection code for tumors under 5 cm.

What documentation supports reporting 21558?

The operative report should identify the neck or anterior thorax site, tumor size, and the extent of the radical resection. Documentation should distinguish the operation from a limited excision or biopsy.

Can an assistant surgeon be reported?

CMS permits payment for an assistant at surgery with this code. Co-surgeon payment requires supporting documentation.

Can modifier 50 be used for bilateral tumors?

No. The code’s descriptor or anatomy makes modifier 50 inappropriate.

How does the 90-day global period affect postoperative billing?

The day-before preoperative visit and related postoperative care for 90 days are included in the global period.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 21558PPRRVU2026_Oct_nonQPP.csv, line 2,007 (RVU26D)

Open CMS sourceHow we calculate rates

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