CPT code 38211: Tumor-cell depletion, stem cell harvest processing2026 Medicare rate & RVUs in Guam

Describes processing a harvested hematopoietic cell product to remove tumor cells before it is prepared for a transplant.

CMS RVU26DEffective Oct 1, 20261 payment locality

CMS doesn’t publish an office rate for 38211 in Guam.

—Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Guam
  2. What 38211 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 38211 covers

This service involves processing a collected hematopoietic progenitor cell product to reduce tumor-cell contamination before the product is used in a transplant. It is associated with transplant preparation for patients with malignancy and is performed by a specialized cell-processing laboratory working with the transplant team. The product being processed is the cell harvest, not a tumor specimen taken for diagnosis. This code distinguishes tumor-cell removal from other types of cell-product manipulation, such as removing T cells or red blood cells.

CPT 38211 has physician fee schedule status I, meaning Medicare does not accept this code as valid for reporting and payment. Medicare uses a different code to report and pay for the service; this CPT code should not be treated as the Medicare reporting code. The service concerns processing of the harvested product, rather than the collection or transplantation procedure itself.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

38211 in Hawaii, Guam, HI

38211 office and facility rates by payment locality
Payment localityOfficeFacility
Hawaii, Guam, HIUnavailableUnavailable

How the 38211 rate is calculated

Each of 38211’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 38211

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.38

1.38 RVUs× 1.000 GPCI

Practice expense0.31

0.31 RVUs× 1.000 GPCI

Malpractice0.15

0.15 RVUs× 1.000 GPCI

Adjusted RVUs

1.8400

Conversion factor

$33.4009

Medicare rate

$61.46

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 38211

38211 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · 38211

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

38211 isn’t priced in this setting.

38211 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 38211

    Tumor-cell depletion, stem cell harvest processing1.38 wRVU

    Not priced

  • 38210

    T-cell depletion, harvest processing1.53 wRVU

    Not priced

  • 38212

    RBC depletion, stem-cell harvest0.92 wRVU

    Not priced

  • 38213

    Platelet depletion, stem cell harvest processing0.23 wRVU

    Not priced

How to choose

38210T-cell depletionHarvest processing
Code 38211 identifies tumor-cell depletion of the harvest; 38210 describes T-cell depletion.
38212RBC depletionStem-cell harvest
Code 38211 identifies tumor-cell depletion. Code 38212 describes red-cell depletion of the harvested product.
38213Platelet depletionStem cell harvest processing
Code 38213 describes platelet depletion, not removal of tumor cells from the harvest.

38211 billing questions

How does this differ from T-cell depletion?

This code describes removing tumor cells from a harvested cell product. Code 38210 describes T-cell depletion, a different type of product manipulation.

Is this the code for collecting the stem cell harvest?

No. It describes processing a collected product to reduce tumor-cell contamination. Codes 38205 and 38206 describe allogeneic and autologous stem cell collection, respectively.

How does it differ from red-cell depletion?

Tumor-cell depletion targets tumor-cell contamination. Code 38212 describes red-cell depletion of a harvest.

Can this CPT code be reported to Medicare?

No. Medicare status I means this code is not valid for Medicare; Medicare uses a different code to report and pay for the service.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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