CPT code 38241: Cell transplant, autologous cells2026 Medicare rate & RVUs in Missouri
Reports infusion of a patient’s own hematopoietic cells as a transplant, commonly after intensive treatment for a hematologic malignancy.
CMS doesn’t publish an office rate for 38241 in Missouri.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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What 38241 covers
CPT 38241 represents transplantation of autologous hematopoietic progenitor cells, such as cells collected from the patient’s peripheral blood or bone marrow. It is typically reported for the transplant infusion during a facility-based treatment course, often after high-dose therapy for a blood cancer. The transplant physician and cellular therapy team coordinate delivery of the patient’s cells; this is distinct from collecting the cells or processing them for storage or infusion.
Report the transplant when the patient’s own hematopoietic cells are infused as the transplant. Documentation should identify the autologous product, the transplant indication, and the infusion performed. CMS lists payment as restricted to specific circumstances, so payment depends on meeting the applicable coverage conditions. When multiple procedures subject to the standard multiple-procedure rule occur in the same session, the highest-valued procedure is paid in full and the others at 50%.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where 38241 pays more and less in Missouri
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
| Payment locality | Office | Facility |
|---|---|---|
| Metropolitan Kansas City, MO | Unavailable | $146.10 |
| Metropolitan St. Louis, MO | Unavailable | $146.85 |
| Rest of Missouri | Unavailable | $142.66 |
How the 38241 rate is calculated
Each of 38241’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 38241
RVUs × geographic indexes × conversion factor
Work2.93
2.93 RVUs× 1.000 GPCI
Practice expense1.33
1.33 RVUs× 1.000 GPCI
Malpractice0.20
0.20 RVUs× 1.000 GPCI
Adjusted RVUs
4.4600
Conversion factor
$33.4009
Medicare rate
$148.97
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for 38241
The CMS indicators that decide how 38241 is paid alongside other services.
CMS payment indicators · 38241
Cell transplant, autologous cells
| Rule | CMS value | What it means |
|---|---|---|
| Global period | XXX | The global surgery concept doesn’t apply. |
| Multiple procedures | 2 | Standard reduction: highest-valued procedure at 100%, others at 50%. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 0 | Physician service: no professional/technical split. |
What modifiers do to the payment
Modifier 51 · payment effect
With and without the modifier
38241 without 51 · national facility
$148.97
Cell transplant, autologous cells
38241-51 · Second procedure: 50%
$74.49
When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).
38241 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 38240Cell transplantAllogeneic, per donor
- Use 38241 for the patient’s own hematopoietic cells; 38240 describes transplantation using cells from an allogeneic donor.
- 38243Cell boostAfter transplant
- 38241 represents an autologous transplant. 38243 is for a hematopoietic cell boost rather than the transplant infusion.
- 38208Stem cell thawingBefore clinical use
- 38208 reports thawing preserved cells. It does not replace 38241 when those cells are infused as an autologous transplant.
38241 billing questions
How is 38241 different from 38240?
38241 is for transplantation of the patient’s own hematopoietic cells. Use 38240 for transplantation of cells from an allogeneic donor.
Does 38241 include cell collection?
No. It represents the transplant infusion, not the earlier collection of autologous cells. Cell collection is separately represented by 38206 when that service is performed.
Can thawing be reported with 38241?
When previously preserved cells are thawed for the transplant, 38208 identifies the thawing service and may be reported with the transplant when performed.
What documentation supports 38241?
Document that the infused cells are the patient’s own hematopoietic cells, the transplant indication, and the transplant infusion. The record should distinguish the infusion from cell collection and processing.
How does the multiple-procedure rule affect 38241?
When multiple procedures subject to the rule are performed in the same session, the highest-valued procedure is paid in full and the others at 50%. CMS also restricts payment for 38241 to specific circumstances.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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