CPT code 52287: Bladder chemodenervation, cystoscopic injection2026 Medicare rate & RVUs in Missouri
Reports cystoscopic injection of a chemodenervation agent into the bladder for conditions such as overactive bladder or neurogenic detrusor overactivity.
Medicare pays $329.53–$352.00 for 52287 in the office in Missouri, from Rest of Missouri to Metropolitan St. Louis, MO. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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What 52287 covers
A urologist typically performs this procedure by passing a cystoscope through the urethra and injecting a chemodenervation agent into the bladder wall. Common indications include overactive bladder with inadequate response or intolerance to medication and neurogenic detrusor overactivity. The code represents the cystoscopic injection service, not a biopsy or treatment of a bladder lesion. When the practice supplies onabotulinumtoxinA, the drug may be reported separately using the applicable drug code.
Report the service for the cystoscopic chemodenervation session; document the indication, agent and dose, injection sites, and procedure performed. The procedure has a 0-day global period, so same-day preoperative and postoperative care is included. When related endoscopies are performed together, endoscopy-family pricing applies. Modifier 50 is inappropriate for this service. Medicare does not pay an assistant at surgery, and co-surgeon and team-surgery reporting are not permitted. The physician fee schedule has different practice-expense inputs for office and facility settings.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where 52287 pays more and less in Missouri
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
3 payment localities
$329.53 to $352.00
| Payment locality | Office | Facility |
|---|---|---|
| Metropolitan Kansas City, MO | $348.45 | $146.78 |
| Metropolitan St. Louis, MO | $352.00 | $147.54 |
| Rest of Missouri | $329.53 | $144.40 |
How the 52287 rate is calculated
Each of 52287’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 52287
RVUs × geographic indexes × conversion factor
Work3.12
3.12 RVUs× 1.000 GPCI
Practice expense7.34
7.34 RVUs× 1.000 GPCI
Malpractice0.43
0.43 RVUs× 1.000 GPCI
Adjusted RVUs
10.8900
Conversion factor
$33.4009
Medicare rate
$363.74
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for 52287
The CMS indicators that decide how 52287 is paid alongside other services.
CMS payment indicators · 52287
Bladder chemodenervation, cystoscopic injection
| Rule | CMS value | What it means |
|---|---|---|
| Global period | 000 | Same-day global: pre- and post-op care on the day of the procedure is included. |
| Multiple procedures | 3 | Endoscopy family rules apply. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 1 | Not paid (statutory restriction). |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 0 | Physician service: no professional/technical split. |
What modifiers do to the payment
Modifier 51 · payment effect
With and without the modifier
52287 without 51 · national office
$363.74
Bladder chemodenervation, cystoscopic injection
52287-51 · Second procedure: 50%
$181.87
When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).
52287 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 52204Cystoscopic biopsyBladder tissue sampling
- Use 52287 for bladder chemodenervation injections. Use 52204 when the cystoscopy includes biopsy of bladder tissue.
- 52224Bladder lesion treatmentLesions under 0.5 cm
- 52287 describes injection for bladder chemodenervation; 52224 is for cystoscopic treatment of a bladder lesion.
- 52214Cystoscopy treatmentFulguration at specified sites
- 52287 involves injections into the bladder wall for chemodenervation. 52214 is used for cystoscopic fulguration or other treatment at specified urinary-tract sites.
52287 billing questions
How is this different from cystoscopy with biopsy?
52287 reports injections intended to chemodenervate the bladder. A biopsy code is for sampling bladder tissue, not for the therapeutic injection.
Can the medication be reported separately?
When the practice supplies onabotulinumtoxinA, report the drug separately using the applicable drug code. The cystoscopic injection service is reported with 52287.
Should modifier 50 be appended?
No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.
What happens when another related endoscopy is performed at the same session?
CMS endoscopy-family pricing applies when related endoscopies are performed together. Documentation should identify each distinct service performed.
What documentation supports 52287?
Document the bladder condition being treated, the chemodenervation agent and dose, the cystoscopic injection procedure, and the sites treated.
Can an assistant or co-surgeon be reported?
Medicare does not pay an assistant at surgery for this service. Co-surgeons and team surgery are not permitted.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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