CPT code 59015: Chorionic villus sampling, placental tissue sampling2026 Medicare rate & RVUs in Florida

Reports prenatal placental villus sampling to obtain fetal genetic material, typically during early pregnancy when diagnostic testing is indicated.

CMS RVU26DEffective Oct 1, 20263 payment localities

Medicare pays $169.17–$198.10 for 59015 in the office in Florida, from Rest of Florida to Miami, FL. Which amount applies depends on the service address.

$169.17–$198.10Office (non-facility)
$127.98–$153.24Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Florida
  2. What 59015 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 59015 covers

A clinician obtains a small sample of chorionic villi from the placenta for prenatal diagnostic testing. Sampling may use a transcervical catheter or a transabdominal needle, with ultrasound used to guide the approach. Maternal-fetal medicine specialists and obstetricians commonly perform the procedure in an outpatient setting when testing for a fetal chromosomal or genetic condition is indicated.

Report 59015 for the sampling procedure, documenting the indication, approach, and specimen obtained. The genetic analysis is a separate laboratory service when performed and reported. Medicare assigns a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to a 50% reduction. Modifier 50 is inappropriate for this sampling. Assistant-at-surgery payment requires documented medical necessity; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 59015 pays more and less in Florida

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$169.17 to $198.10

$169.17$183.63$198.10
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
59015 office and facility rates by payment locality
Payment localityOfficeFacility
Fort Lauderdale, FL$179.87$136.22
Miami, FL$198.10$153.24
Rest of Florida$169.17$127.98

How the 59015 rate is calculated

Each of 59015’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 59015

RVUs × geographic indexes × conversion factor

Office or facility?

Work2.15

2.15 RVUs× 1.000 GPCI

Practice expense1.98

1.98 RVUs× 1.000 GPCI

Malpractice0.68

0.68 RVUs× 1.000 GPCI

Adjusted RVUs

4.8100

Conversion factor

$33.4009

Medicare rate

$160.66

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 59015

The CMS indicators that decide how 59015 is paid alongside other services.

CMS payment indicators · 59015

Chorionic villus sampling, placental tissue sampling

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

59015 without 51 · national office

$160.66

Chorionic villus sampling, placental tissue sampling

59015-51 · Second procedure: 50%

$80.33

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

59015 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 59015

    Chorionic villus sampling, placental tissue sampling2.15 wRVU

    $160.66

  • 59000

    Amniocentesis, diagnostic fluid sampling1.27 wRVU

    $119.58−$41.08

  • 59012

    Cordocentesis, prenatal fetal blood sampling3.35 wRVU

    Not priced

  • 76945

    CVS ultrasound guidance, during CVS0 wRVU

    Not priced

How to choose

59000AmniocentesisDiagnostic fluid sampling
Use 59015 when placental chorionic villi are sampled; use 59000 when amniotic fluid is obtained for diagnostic testing.
59012CordocentesisPrenatal fetal blood sampling
59012 involves prenatal fetal blood sampling by cord puncture. It is not the code for obtaining placental villi.
76945CVS ultrasound guidanceDuring CVS
76945 reports ultrasound guidance for chorionic villus sampling, not the tissue-sampling procedure itself.

59015 billing questions

How is chorionic villus sampling different from diagnostic amniocentesis?

59015 reports sampling placental villi, while 59000 reports sampling amniotic fluid. The appropriate procedure depends on the diagnostic method and specimen obtained.

Can ultrasound guidance be reported with 59015?

CPT 76945 describes ultrasound guidance for chorionic villus sampling. Report it when the guidance service is performed and documented.

Is the genetic laboratory analysis included in 59015?

No. Code 59015 represents obtaining the placental tissue; laboratory analysis is a distinct service when performed and reported.

Should modifier 50 be used for sampling from both sides of the placenta?

No. Modifier 50 is inappropriate for this procedure. Document the sampling performed and the approach used.

What same-session payment rules affect 59015?

Same-day preoperative and postoperative care is included in its 0-day global period. In a session with multiple procedures, the highest-valued procedure is paid in full and other procedures are subject to a 50% reduction.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 59015PPRRVU2026_Oct_nonQPP.csv, line 6,627 (RVU26D)

Open CMS sourceHow we calculate rates

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