CPT code 60100: Thyroid biopsy, percutaneous needle2026 Medicare rate & RVUs in Missouri

Report this procedure for percutaneous needle sampling of thyroid tissue, such as a nodule, when the service is not a fine-needle aspiration biopsy.

CMS RVU26DEffective Oct 1, 20263 payment localities3.8K Medicare services in 2024

Medicare pays $101.21–$106.06 for 60100 in the office in Missouri, from Rest of Missouri to Metropolitan St. Louis, MO. Which amount applies depends on the service address.

$101.21–$106.06Office (non-facility)
$64.07–$65.04Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Missouri
  2. What 60100 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 60100 covers

A clinician obtains thyroid tissue by passing a needle through the skin into a thyroid nodule or other focal abnormality. The procedure is commonly performed by an endocrinologist, radiologist, or surgeon in an office, outpatient department, or imaging suite. This code describes needle tissue biopsy; when the service is specifically fine-needle aspiration, use the applicable FNA code instead.

Report one service for the percutaneous thyroid biopsy and document the target, needle approach, tissue obtained, and any imaging guidance performed. The code has a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures are performed in one session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% multiple procedure reduction. Modifier 50 is inappropriate for this code. Medicare does not pay an assistant at surgery, and co-surgeon and team-surgery reporting are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 60100 pays more and less in Missouri

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$101.21 to $106.06

$101.21$103.63$106.06
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
60100 office and facility rates by payment locality
Payment localityOfficeFacility
Metropolitan Kansas City, MO$105.24$64.79
Metropolitan St. Louis, MO$106.06$65.04
Rest of Missouri$101.21$64.07

How the 60100 rate is calculated

Each of 60100’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 60100

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.52

1.52 RVUs× 1.000 GPCI

Practice expense1.56

1.56 RVUs× 1.000 GPCI

Malpractice0.17

0.17 RVUs× 1.000 GPCI

Adjusted RVUs

3.2500

Conversion factor

$33.4009

Medicare rate

$108.55

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 60100

The CMS indicators that decide how 60100 is paid alongside other services.

CMS payment indicators · 60100

Thyroid biopsy, percutaneous needle

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

60100 without 51 · national office

$108.55

Thyroid biopsy, percutaneous needle

60100-51 · Second procedure: 50%

$54.28

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

60100 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 60100

    Thyroid biopsy, percutaneous needle1.52 wRVU

    $108.55

  • 10005

    Ultrasound-guided FNA, first lesion1.42 wRVU

    $132.27+$23.72

  • 10021

    Fine needle aspiration, first lesion, no imaging1 wRVU

    $100.87−$7.68

  • 60200

    Thyroid surgery, focal lesion or isthmus9.77 wRVU

    Not priced

How to choose

10005Ultrasound-guided FNAFirst lesion
Use 10005 for fine-needle aspiration biopsy with ultrasound guidance. Use 60100 for percutaneous needle tissue biopsy rather than an FNA service.
10021Fine needle aspirationFirst lesion, no imaging
Use 10021 for fine-needle aspiration biopsy without imaging guidance. The distinction is the FNA method, not simply the thyroid site.
60200Thyroid surgeryFocal lesion or isthmus
60200 describes surgical excision of a thyroid lesion, not percutaneous needle sampling. Choose it when the lesion is removed surgically.

60100 billing questions

How is 60100 different from a thyroid FNA code?

60100 represents percutaneous needle biopsy for tissue sampling. Use the FNA code set when the service is specifically fine-needle aspiration, with the code determined in part by whether imaging guidance is included.

Can imaging guidance be reported separately?

The biopsy code does not describe imaging guidance. If guidance is performed and separately reportable, document the modality, guidance, and needle placement; ultrasound guidance may be reported with 76942 when its requirements are met.

What documentation supports 60100?

Record the thyroid target, percutaneous needle approach, tissue sampling performed, and the specimen submitted. Include the imaging guidance details when guidance is performed.

Does 60100 have a global period?

It has a 0-day global period. Same-day preoperative and postoperative care is included in the procedure.

Can modifier 50 or an assistant-at-surgery modifier be used?

Modifier 50 is inappropriate for this code. Medicare does not pay an assistant at surgery for 60100.

How does Medicare handle other procedures performed in the same session?

The highest-valued procedure is paid in full, and other procedures in the session are subject to the standard multiple procedure reduction. Co-surgeon and team-surgery reporting are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 60100PPRRVU2026_Oct_nonQPP.csv, line 6,693 (RVU26D)

Open CMS sourceHow we calculate rates

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