CPT code 64721: Carpal tunnel release, median nerve at carpal tunnel2026 Medicare rate & RVUs in Maine

Reports open surgical release of the median nerve at the carpal tunnel, typically by dividing the transverse carpal ligament to relieve compression.

CMS RVU26DEffective Oct 1, 20262 payment localities153.3K Medicare services in 2024

Medicare pays $447.14–$467.85 for 64721 in the office in Maine, from Rest of Maine to Southern Maine, ME. Which amount applies depends on the service address.

$447.14–$467.85Office (non-facility)
$392.44–$408.93Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Maine
  2. What 64721 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 64721 covers

A hand or orthopedic surgeon typically performs this open operation for median nerve compression at the wrist, often when carpal tunnel symptoms warrant surgical decompression. The surgeon opens the wrist or palm and releases the transverse carpal ligament to reduce pressure on the median nerve. The procedure is commonly performed in an operating room or ambulatory surgery setting.

Report 64721 for the documented open median nerve release at the carpal tunnel; the operative note should identify the side and describe the release performed. The code has a 90-day global period, including the day-before preoperative visit and related postoperative care during that period. For multiple procedures in one session, the highest-valued procedure is paid in full and others at 50%. Modifier 50 identifies bilateral surgery, paid at 150%. Medicare does not pay an assistant at surgery, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 64721 pays more and less in Maine

64721 office and facility rates by payment locality
Payment localityOfficeFacility
Rest of Maine$447.14$392.44
Southern Maine, ME$467.85$408.93

How the 64721 rate is calculated

Each of 64721’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 64721

RVUs × geographic indexes × conversion factor

Office or facility?

Work4.85

4.85 RVUs× 1.000 GPCI

Practice expense8.61

8.61 RVUs× 1.000 GPCI

Malpractice0.99

0.99 RVUs× 1.000 GPCI

Adjusted RVUs

14.4500

Conversion factor

$33.4009

Medicare rate

$482.64

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 64721

64721 has a 90-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 64721

Carpal tunnel release, median nerve at carpal tunnel

RuleCMS valueWhat it means
Global period090Major surgery: the day before, the day of, and 90 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)1Bilateral with modifier 50 pays 150% of the fee schedule amount.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.11/0.76/0.13Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 64721

Carpal tunnel release, median nerve at carpal tunnel

90-day global period ends

Dec 30, 2026

Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).

Visit on Oct 31, 2026

Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.

  • 24Unrelated E/M visit by the same physician
  • 79Unrelated procedure (starts its own global period)
  • 58Staged, more extensive, or therapy procedure that was planned
  • 78Unplanned return to the operating room for a related complication
SurgeryVisit
Sep 23, 2026Jan 10, 2027

Pre-op dayGlobal period

What modifiers do to the payment

Modifier 50 · payment effect

With and without the modifier

64721 without 50 · national office

$482.64

Carpal tunnel release, median nerve at carpal tunnel

64721-50 · Bilateral: 150%

$723.96

Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).

When to use modifier 50

64721 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 64721

    Carpal tunnel release, median nerve at carpal tunnel4.85 wRVU

    $482.64

  • 29848

    Carpal tunnel release, endoscopic approach6.23 wRVU

    Not priced

  • 64728

    Carpal tunnel decompression, median nerve2.7 wRVU

    $1,343.05+$860.41

  • 64719

    Ulnar nerve surgery, at wrist4.85 wRVU

    Not priced

How to choose

29848Carpal tunnel releaseEndoscopic approach
29848 describes endoscopic carpal tunnel release. Use 64721 for the open median nerve release.
64728Carpal tunnel decompressionMedian nerve
Both concern median nerve decompression at the carpal tunnel, but they are distinct procedure codes. Match the code to the operative service documented rather than treating them as interchangeable.
64719Ulnar nerve surgeryAt wrist
64719 addresses ulnar nerve decompression at the wrist, not median nerve compression within the carpal tunnel.

64721 billing questions

How does 64721 differ from endoscopic carpal tunnel release?

Use 64721 for the open median nerve release at the carpal tunnel. The endoscopic approach is reported with 29848.

Can internal neurolysis be reported with 64721?

CPT 64727 is an add-on for qualifying internal neurolysis requiring an operating microscope. The operative documentation should support that additional work.

How is bilateral carpal tunnel release reported?

Report modifier 50 for bilateral surgery; CMS pays the bilateral procedure at 150%.

Are routine postoperative visits separately payable?

Related postoperative care during the 90-day global period is included, along with the day-before preoperative visit.

Can an assistant or co-surgeon be billed for 64721?

Medicare does not pay an assistant at surgery for this code. Co-surgeons and team surgery are not permitted.

What happens when 64721 is performed with another procedure?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and other procedures in the same session are paid at 50%.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 64721PPRRVU2026_Oct_nonQPP.csv, line 7,210 (RVU26D)

Open CMS sourceHow we calculate rates

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