CPT code 65781: Ocular reconstruction, limbal stem cell allograft2026 Medicare rate & RVUs in Chicago, IL
Reports ocular surface reconstruction using donor limbal stem cells for limbal stem cell deficiency, such as after severe chemical injury.
In Chicago, IL, Medicare pays $1,190.49 for 65781 in a facility. There’s no office rate.
Check a contract rate as a % of Medicare · 65781 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 65781 covers
An ophthalmic surgeon uses donor limbal tissue containing stem cells to rebuild the ocular surface when the patient’s limbal stem cell function is inadequate. The donor tissue may come from a cadaveric or living donor. This operation is used for significant limbal stem cell deficiency, including cases following severe chemical or thermal injury, and is generally performed in a surgical facility.
Report 65781 when the reconstruction uses an allogeneic limbal stem cell graft; document the donor tissue and the surgical work performed. The code has a 90-day global period, including the day-before preoperative visit and related postoperative care during that period. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard multiple procedure reduction. For bilateral reporting with modifier 50, CMS pays at 150%. Assistant-at-surgery payment may be available; co-surgeons require supporting documentation, and team surgery is not permitted.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Chicago, IL compares for 65781
Across 109 of 109 payment localities, the facility rate for 65781 runs from $1,031.71 in Arkansas to $1,428.75 in Alaska. Chicago, IL pays $1,190.49. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Chicago, IL · this page$1,190.49
- East St. Louis, IL · Illinois$1,131.89−$58.60
- Rest of Illinois · Illinois$1,107.26−$83.23
- Suburban Chicago, IL · Illinois$1,176.53−$13.96
- Los Angeles, CA · California$1,220.09+$29.60
- Washington, DC area · District of Columbia$1,246.49+$56.00
- Miami, FL · Florida$1,214.83+$24.34
Other areas in Illinois first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| Manhattan, NYNew York | — | $1,266.92 |
| AlaskaAlaska | — | $1,428.75 |
| AlabamaAlabama | — | $1,041.88 |
| ArkansasArkansas | — | $1,031.71 |
| ArizonaArizona | — | $1,101.12 |
| Bakersfield, CACalifornia | — | $1,162.31 |
| Chico, CACalifornia | — | $1,157.69 |
| El Centro, CACalifornia | — | $1,157.92 |
| Fresno, CACalifornia | — | $1,157.69 |
| Hanford, CACalifornia | — | $1,157.69 |
| Madera, CACalifornia | — | $1,157.69 |
| Merced, CACalifornia | — | $1,157.69 |
| Modesto, CACalifornia | — | $1,157.69 |
| Napa, CACalifornia | — | $1,291.22 |
| Oxnard, CACalifornia | — | $1,209.99 |
| Redding, CACalifornia | — | $1,157.69 |
| Rest of CaliforniaCalifornia | — | $1,157.69 |
| Riverside, CACalifornia | — | $1,173.21 |
| Sacramento, CACalifornia | — | $1,201.41 |
| Salinas, CACalifornia | — | $1,196.51 |
| San Diego, CACalifornia | — | $1,214.15 |
| Marin County, CACalifornia | — | $1,352.43 |
| San Francisco, CACalifornia | — | $1,350.83 |
| San Benito County, CACalifornia | — | $1,380.44 |
| Santa Clara County, CACalifornia | — | $1,373.90 |
| San Luis Obispo, CACalifornia | — | $1,178.54 |
| Santa Cruz, CACalifornia | — | $1,217.77 |
| Santa Maria, CACalifornia | — | $1,198.14 |
| Santa Rosa, CACalifornia | — | $1,229.39 |
| Stockton, CACalifornia | — | $1,157.69 |
| Vallejo, CACalifornia | — | $1,288.91 |
| Visalia, CACalifornia | — | $1,157.69 |
| Yuba City, CACalifornia | — | $1,157.69 |
| ColoradoColorado | — | $1,150.75 |
| ConnecticutConnecticut | — | $1,181.99 |
| DelawareDelaware | — | $1,115.32 |
| Fort Lauderdale, FLFlorida | — | $1,167.30 |
| Rest of FloridaFlorida | — | $1,125.29 |
| Atlanta, GAGeorgia | — | $1,141.94 |
| Rest of GeorgiaGeorgia | — | $1,079.60 |
| Hawaii, Guam, HIHawaii | — | $1,169.55 |
| IowaIowa | — | $1,053.32 |
| IdahoIdaho | — | $1,059.32 |
| IndianaIndiana | — | $1,063.33 |
| KansasKansas | — | $1,053.02 |
| KentuckyKentucky | — | $1,065.10 |
| New Orleans, LALouisiana | — | $1,100.73 |
| Rest of LouisianaLouisiana | — | $1,065.19 |
| Metropolitan Boston, MAMassachusetts | — | $1,236.07 |
| Rest of MassachusettsMassachusetts | — | $1,148.54 |
| Baltimore area, MDMaryland | — | $1,178.96 |
| Rest of MarylandMaryland | — | $1,130.80 |
| Rest of MaineMaine | — | $1,066.34 |
| Southern Maine, MEMaine | — | $1,101.20 |
| Detroit, MIMichigan | — | $1,138.27 |
| Rest of MichiganMichigan | — | $1,086.82 |
| MinnesotaMinnesota | — | $1,103.85 |
| Metropolitan Kansas City, MOMissouri | — | $1,092.27 |
| Metropolitan St. Louis, MOMissouri | — | $1,099.75 |
| Rest of MissouriMissouri | — | $1,054.79 |
| MississippiMississippi | — | $1,043.23 |
| MontanaMontana | — | $1,122.84 |
| North CarolinaNorth Carolina | — | $1,073.44 |
| North DakotaNorth Dakota | — | $1,094.96 |
| NebraskaNebraska | — | $1,056.30 |
| New HampshireNew Hampshire | — | $1,136.94 |
| Northern New JerseyNew Jersey | — | $1,240.96 |
| Rest of New JerseyNew Jersey | — | $1,195.76 |
| New MexicoNew Mexico | — | $1,092.15 |
| NevadaNevada | — | $1,115.56 |
| NYC suburbs and Long Island, NYNew York | — | $1,292.78 |
| Poughkeepsie and northern NYC suburbs, NYNew York | — | $1,205.49 |
| Queens, NYNew York | — | $1,269.84 |
| Rest of New YorkNew York | — | $1,084.70 |
| OhioOhio | — | $1,081.12 |
| OklahomaOklahoma | — | $1,060.54 |
| Portland, OROregon | — | $1,174.17 |
| Rest of OregonOregon | — | $1,107.01 |
| Metropolitan Philadelphia, PAPennsylvania | — | $1,162.55 |
| Rest of PennsylvaniaPennsylvania | — | $1,080.58 |
| Puerto RicoPuerto Rico | — | $1,127.57 |
| Rhode IslandRhode Island | — | $1,145.08 |
| South CarolinaSouth Carolina | — | $1,079.02 |
| South DakotaSouth Dakota | — | $1,091.67 |
| TennesseeTennessee | — | $1,057.00 |
| Austin, TXTexas | — | $1,146.88 |
| Beaumont, TXTexas | — | $1,075.95 |
| Brazoria, TXTexas | — | $1,112.94 |
| Dallas, TXTexas | — | $1,119.63 |
| Fort Worth, TXTexas | — | $1,115.39 |
| Galveston, TXTexas | — | $1,116.17 |
| Houston, TXTexas | — | $1,141.98 |
| Rest of TexasTexas | — | $1,093.64 |
| UtahUtah | — | $1,089.04 |
| VirginiaVirginia | — | $1,100.85 |
| Virgin Islands, VIUnited States Virgin Islands | — | $1,127.57 |
| VermontVermont | — | $1,094.82 |
| Rest of WashingtonWashington | — | $1,145.07 |
| King County, WAWashington | — | $1,253.95 |
| WisconsinWisconsin | — | $1,069.98 |
| West VirginiaWest Virginia | — | $1,079.70 |
| WyomingWyoming | — | $1,110.69 |
65781 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | No published base rate | 1 |
| AL | No published base rate | 1 |
| AR | No published base rate | 1 |
| AZ | No published base rate | 1 |
| CA | No published base rate | 29 |
| CO | No published base rate | 1 |
| CT | No published base rate | 1 |
| DC | No published base rate | 1 |
| DE | No published base rate | 1 |
| FL | No published base rate | 3 |
| GA | No published base rate | 2 |
| GU | No published base rate | 1 |
| HI | No published base rate | 1 |
| IA | No published base rate | 1 |
| ID | No published base rate | 1 |
| IL | No published base rate | 4 |
| IN | No published base rate | 1 |
| KS | No published base rate | 1 |
| KY | No published base rate | 1 |
| LA | No published base rate | 2 |
| MA | No published base rate | 2 |
| MD | No published base rate | 3 |
| ME | No published base rate | 2 |
| MI | No published base rate | 2 |
| MN | No published base rate | 1 |
| MO | No published base rate | 3 |
| MS | No published base rate | 1 |
| MT | No published base rate | 1 |
| NC | No published base rate | 1 |
| ND | No published base rate | 1 |
| NE | No published base rate | 1 |
| NH | No published base rate | 1 |
| NJ | No published base rate | 2 |
| NM | No published base rate | 1 |
| NV | No published base rate | 1 |
| NY | No published base rate | 5 |
| OH | No published base rate | 1 |
| OK | No published base rate | 1 |
| OR | No published base rate | 2 |
| PA | No published base rate | 2 |
| PR | No published base rate | 1 |
| RI | No published base rate | 1 |
| SC | No published base rate | 1 |
| SD | No published base rate | 1 |
| TN | No published base rate | 1 |
| TX | No published base rate | 8 |
| UT | No published base rate | 1 |
| VA | No published base rate | 2 |
| VI | No published base rate | 1 |
| VT | No published base rate | 1 |
| WA | No published base rate | 2 |
| WI | No published base rate | 1 |
| WV | No published base rate | 1 |
| WY | No published base rate | 1 |
How the 65781 rate is calculated
Each of 65781’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 65781
RVUs × geographic indexes × conversion factor
Work17.69
17.69 RVUs× 1.000 GPCI
Practice expense14.52
14.52 RVUs× 1.000 GPCI
Malpractice1.41
1.41 RVUs× 1.000 GPCI
Adjusted RVUs
33.6200
Conversion factor
$33.4009
Medicare rate
$1,122.94
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Chicago, IL inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
7,343
- Code
- 65781
- Physician work
- 17.69
- Practice expense
- 14.52
- Malpractice
- 1.41
GPCI2026.csv
48
- Locality
- Chicago, IL
- Physician work
- 1.007
- Practice expense
- 1.005
- Malpractice
- 2.295
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 17.69 | × 1.007 | 17.8138 |
| Practice expense | 14.52 | × 1.005 | 14.5926 |
| Malpractice | 1.41 | × 2.295 | 3.2359 |
| Total RVUs | 35.6424 | ||
| Conversion factor | × 33.4009 | ||
Facility rate, Chicago, IL$1190.49
Facility: (17.69 × 1.007 + 14.52 × 1.005 + 1.41 × 2.295) × $33.4009 = $1190.49
Payment rules and modifiers for 65781
65781 has a 90-day global period: related visits in that window are included in the surgery payment.
CMS payment indicators · 65781
Ocular reconstruction, limbal stem cell allograft
| Rule | CMS value | What it means |
|---|---|---|
| Global period | 090 | Major surgery: the day before, the day of, and 90 days after are included. |
| Multiple procedures | 2 | Standard reduction: highest-valued procedure at 100%, others at 50%. |
| Bilateral (modifier 50) | 1 | Bilateral with modifier 50 pays 150% of the fee schedule amount. |
| Assistant at surgery (80/81/82/AS) | 2 | Paid. |
| Co-surgeons (62) | 1 | Permitted with supporting documentation. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 0 | Physician service: no professional/technical split. |
| Split (54/55/56) | 0.10/0.70/0.20 | Share of the payment for pre-op, the procedure itself, and post-op care. |
Global surgery period · 65781
Ocular reconstruction, limbal stem cell allograft
90-day global period ends
Dec 30, 2026
Covers Sep 30, 2026 through Dec 30, 2026 (92 days, including the day before surgery).
Visit on Oct 31, 2026
Day 30 of the 90-day post-op period: related follow-up care is included in the surgical payment.
Pre-op dayGlobal period
What modifiers do to the payment
Modifier 50 · payment effect
With and without the modifier
65781 without 50 · national facility
$1,122.94
Ocular reconstruction, limbal stem cell allograft
65781-50 · Bilateral: 150%
$1,684.41
Both sides on one line with modifier 50 are paid at 150% of the fee schedule amount (subject to multiple-procedure rules with other procedures).
How 65781 has changed in Chicago, IL
65781 · Office / nonfacility
Rate unavailable
Effective 2026-10-01
A rate is unavailable in one of these releases, so a change cannot be calculated.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | Not available in this setting | $1,190.49 | RVU26D |
| 2026-07-01 | Not available in this setting | $1,190.49 | RVU26C |
| 2026-04-01 | Not available in this setting | $1,190.49 | RVU26B |
| 2026-01-01 | Not available in this setting | $1,190.49 | RVU26A |
| 2025-10-01 | Not available in this setting | $1,338.09 | RVU25D |
| 2025-07-01 | Not available in this setting | $1,338.09 | RVU25C |
| 2025-04-01 | Not available in this setting | $1,338.09 | RVU25B |
| 2025-01-01 | Not available in this setting | $1,338.09 | RVU25A |
| 2024-10-01 | Not available in this setting | $1,377.01 | RVU24D |
| 2024-07-01 | Not available in this setting | $1,377.01 | RVU24C |
| 2024-04-01 | Not available in this setting | $1,377.01 | RVU24B |
| 2024-03-09 | Not available in this setting | $1,377.01 | RVU24AR |
| 2024-01-01 | Not available in this setting | $1,354.54 | RVU24A |
| 2023-10-01 | Not available in this setting | $1,391.36 | RVU23D |
| 2023-07-01 | Not available in this setting | $1,391.36 | RVU23C |
| 2023-04-01 | Not available in this setting | $1,391.36 | RVU23B |
| 2023-01-01 | Not available in this setting | $1,391.36 | RVU23A |
| 2022-10-01 | Not available in this setting | $1,405.98 | RVU22D |
| 2022-07-01 | Not available in this setting | $1,405.98 | RVU22C |
| 2022-04-01 | Not available in this setting | $1,405.98 | RVU22B |
| 2022-01-01 | Not available in this setting | $1,405.98 | RVU22A |
| 2021-10-01 | Not available in this setting | $1,414.66 | RVU21D |
| 2021-07-01 | Not available in this setting | $1,414.66 | RVU21C |
| 2021-04-01 | Not available in this setting | $1,414.66 | RVU21B |
| 2021-01-01 | Not available in this setting | $1,414.66 | RVU21A |
| 2020-10-01 | Not available in this setting | $1,434.11 | RVU20D |
| 2020-07-01 | Not available in this setting | $1,434.11 | RVU20C |
| 2020-04-01 | Not available in this setting | $1,434.11 | RVU20B |
| 2020-01-01 | Not available in this setting | $1,434.11 | RVU20A |
| 2019-10-01 | Not available in this setting | $1,437.76 | RVU19D |
| 2019-07-01 | Not available in this setting | $1,437.76 | RVU19C |
| 2019-04-01 | Not available in this setting | $1,437.76 | RVU19B |
| 2019-01-01 | Not available in this setting | $1,437.76 | RVU19A |
| 2018-10-01 | Not available in this setting | $1,439.91 | RVU18D |
| 2018-07-01 | Not available in this setting | $1,439.91 | RVU18C |
| 2018-04-01 | Not available in this setting | $1,439.91 | RVU18B |
| 2018-01-01 | Not available in this setting | $1,439.91 | RVU18AR1 |
| 2017-10-01 | Not available in this setting | $1,433.81 | RVU17D |
| 2017-07-01 | Not available in this setting | $1,433.81 | RVU17C |
| 2017-04-01 | Not available in this setting | $1,433.81 | RVU17B |
| 2017-01-01 | Not available in this setting | $1,433.81 | RVU17A |
| 2016-10-01 | Not available in this setting | $1,435.14 | RVU16D |
| 2016-07-01 | Not available in this setting | $1,435.14 | RVU16C |
| 2016-04-01 | Not available in this setting | $1,435.14 | RVU16B |
| 2016-01-01 | Not available in this setting | $1,435.14 | RVU16A |
| 2015-10-01 | Not available in this setting | $1,438.08 | RVU15D |
| 2015-07-01 | Not available in this setting | $1,438.08 | RVU15C |
| 2015-04-01 | Not available in this setting | $1,430.92 | RVU15B |
| 2015-01-01 | Not available in this setting | $1,430.92 | RVU15A |
| 2014-10-01 | Not available in this setting | $1,440.55 | RVU14D |
| 2014-07-01 | Not available in this setting | $1,440.55 | RVU14C |
| 2014-04-01 | Not available in this setting | $1,440.55 | RVU14B |
| 2014-01-01 | Not available in this setting | $1,440.55 | RVU14A |
| 2013-10-01 | Not available in this setting | $1,437.02 | RVU13D |
| 2013-07-01 | Not available in this setting | Rate data unavailable | RVU13C |
| 2013-04-01 | Not available in this setting | Rate data unavailable | RVU13B |
| 2013-01-01 | Not available in this setting | Rate data unavailable | RVU13AR |
Where the Chicago, IL rate applies
Chicago, IL is a Medicare payment area, not a city. Our Census mapping connects it to 137 cities and communities in Illinois. Some span more than one payment area; confirm with the service ZIP.
- 65781 in Chicago · multiple payment areas
- Alsip
- Arlington Heights
- 65781 in Barrington · multiple payment areas
- 65781 in Barrington Hills · multiple payment areas
- 65781 in Bartlett · multiple payment areas
- Bedford Park
- Bellwood
65781 billing questions
How is 65781 different from 65782?
65781 is for limbal stem cells from a donor. 65782 is for an autologous graft using the patient’s own tissue.
When would 65780 be reported instead?
65780 describes ocular surface reconstruction using a multilayer amniotic membrane approach. Choose based on the graft and reconstruction performed, not just the diagnosis.
Does 65781 have a global period?
Yes. Its 90-day global period includes the day-before preoperative visit and related postoperative care during the following 90 days.
How is bilateral 65781 paid?
CMS lists bilateral reporting with modifier 50 at 150%. The operative documentation should support surgery on both eyes.
Can an assistant or co-surgeon be reported?
Assistant-at-surgery payment may be available. Co-surgeons are paid only with supporting documentation; team surgery is not permitted.
What documentation supports reporting 65781?
Document the limbal stem cell deficiency, the donor source of the graft, and the operative reconstruction performed.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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