CPT code 78580: Lung perfusion scan, perfusion only2026 Medicare rate & RVUs in Missouri

Reports nuclear medicine imaging of pulmonary blood flow when a perfusion-only lung study is performed, including evaluation for suspected pulmonary embolism.

CMS RVU26DEffective Oct 1, 20263 payment localities31.4K Medicare services in 2024

Medicare pays $184.14–$200.66 for 78580 in the office in Missouri, from Rest of Missouri to Metropolitan St. Louis, MO. Which amount applies depends on the service address.

$184.14–$200.66Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Missouri
  2. What 78580 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 78580 covers

This nuclear medicine study maps blood flow through the lungs after intravenous administration of radiolabeled particles. Gamma-camera images show how perfusion is distributed across the lungs. Common reasons include suspected pulmonary embolism, assessment of pulmonary vascular perfusion, and evaluation of functioning lung before selected thoracic surgery. A nuclear medicine technologist acquires the images, which a radiologist or nuclear medicine physician interprets in a hospital or outpatient imaging setting.

Report 78580 for perfusion imaging alone. When ventilation and perfusion imaging are both performed, 78582 describes the combined examination. Documentation should support the clinical indication, radiopharmaceutical administration, images obtained, and interpretation. The service has separately priced professional and technical components: modifier 26 identifies interpretation, modifier TC identifies equipment and staff, and billing without either modifier represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 78580 pays more and less in Missouri

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$184.14 to $200.66

$184.14$192.40$200.66
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
78580 office and facility rates by payment locality
Payment localityOfficeFacility
Metropolitan Kansas City, MO$198.22Unavailable
Metropolitan St. Louis, MO$200.66Unavailable
Rest of Missouri$184.14Unavailable

How the 78580 rate is calculated

Each of 78580’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 78580

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.72

0.72 RVUs× 1.000 GPCI

Practice expense5.47

5.47 RVUs× 1.000 GPCI

Malpractice0.08

0.08 RVUs× 1.000 GPCI

Adjusted RVUs

6.2700

Conversion factor

$33.4009

Medicare rate

$209.42

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 78580

The CMS indicators that decide how 78580 is paid alongside other services.

CMS payment indicators · 78580

Lung perfusion scan, perfusion only

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

78580 without 26 · national office

$209.42

Lung perfusion scan, perfusion only

78580-26 · Professional component

$33.73

Pays only the interpretation and report.

When to use modifier 26

78580 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 78580

    Lung perfusion scan, perfusion only0.72 wRVU

    $209.42

  • 78579

    Lung scan, ventilation only0.48 wRVU

    $166.34−$43.08

  • 78582

    Lung scan, ventilation and perfusion1.04 wRVU

    $290.59+$81.17

  • 78597

    Lung perfusion, differential quantification0.73 wRVU

    $180.03−$29.39

  • 78598

    Lung V/Q imaging, differential ventilation and perfusion0.83 wRVU

    $264.87+$55.45

How to choose

78579Lung scanVentilation only
78579 reports lung ventilation imaging. Choose 78580 when the study images pulmonary blood flow rather than ventilation.
78582Lung scanVentilation and perfusion
78582 describes both ventilation and perfusion imaging in the combined examination. Use 78580 when only perfusion imaging is performed.
78597Lung perfusionDifferential quantification
78597 is for quantitative differential pulmonary perfusion imaging; 78580 reports perfusion imaging without that quantitative differential service.
78598Lung V/Q imagingDifferential ventilation and perfusion
78598 describes combined ventilation and perfusion imaging with quantitative differential assessment. It is distinct from perfusion-only imaging reported with 78580.

78580 billing questions

When should 78580 be reported instead of 78582?

Use 78580 when the examination includes perfusion imaging only. When both ventilation and perfusion imaging are performed, report the combined examination with 78582.

What do modifiers 26 and TC identify?

Modifier 26 identifies the professional interpretation component, and modifier TC identifies the technical component, including equipment and staff. Without either modifier, the claim represents the global service.

Can 78580 be reported with 78579 for a ventilation-perfusion study?

When both ventilation and perfusion imaging are performed as a combined examination, 78582 describes that service. Do not report 78580 as though it represented the entire combined study.

How does 78580 differ from quantitative differential perfusion imaging?

78580 reports perfusion imaging without the quantitative differential study described by 78597. Select the code that matches the service performed and documented.

What documentation supports 78580?

The record should identify the indication, radiopharmaceutical administration, images acquired, and the interpreting clinician's findings. It should also make clear whether the billed service is professional, technical, or global.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 78580PPRRVU2026_Oct_nonQPP.csv, line 9,428 (RVU26D)

Open CMS sourceHow we calculate rates

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