CPT code 80074: Hepatitis panel, four viral markers2026 Medicare lab fee · Clinical Laboratory Fee Schedule
This four-marker serology panel evaluates suspected acute viral hepatitis, including cases with jaundice, compatible symptoms, or elevated liver enzymes.
Medicare pays $47.63 for 80074 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$47.63
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 80074 covers
This blood test combines serology for acute hepatitis A and B with hepatitis B surface antigen and hepatitis C antibody. The panel includes IgM antibodies to hepatitis A and hepatitis B core antigen, plus tests for hepatitis B surface antigen and hepatitis C antibody. Clinical laboratories typically perform it on serum for patients with jaundice, dark urine, nausea, fatigue, or elevated liver enzymes when viral hepatitis is part of the evaluation. Primary care clinicians, emergency clinicians, and hospital-based providers may order it.
Report 80074 when all four panel tests are performed; when fewer than all four are performed, report the applicable individual assay code or codes. Medicare pays this service only under the CLFS. The 2026 national CLFS amount is $47.63, unchanged since 2020; one amount applies nationwide, without locality or office/facility adjustment. The code has no separate physician fee schedule payment.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 80074
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 80074. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 80074 with status X (excluded by statute), so the test itself is paid only from the CLFS.
80074 on the lab fee schedule since 2020
80074 · CLFS 2026 Q4 (current)
$47.63
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
80074 compared with similar tests
- 80076Liver panelSeven liver chemistry tests$8.17
- 80076 evaluates liver function with chemistry tests. Choose 80074 for the acute viral hepatitis serology workup; both may be ordered when evaluating liver injury and its possible cause.
- 86709Hepatitis AIgM antibody$11.26
- 86709 is the hepatitis A IgM antibody assay alone. Use 80074 when the full four-marker acute hepatitis panel is performed.
- 86803Hepatitis C antibodyScreening antibody assay$14.27
- 86803 is a hepatitis C antibody test alone. It does not include the hepatitis A and B markers in 80074.
80074 billing questions
When should 80074 be reported instead of individual hepatitis assay codes?
Report 80074 when all four tests are performed. When fewer than all four are performed, report the applicable individual assay codes.
Which tests are included in this panel?
It includes hepatitis A IgM antibody, hepatitis B core IgM antibody, hepatitis B surface antigen, and hepatitis C antibody.
Can the component assays also be billed separately?
Do not separately report the included assays for the same complete panel service. Individual assay codes are appropriate when only selected component tests are performed rather than the complete panel.
How does Medicare pay 80074?
Medicare pays it under the CLFS, with one national amount applying across localities and office and facility settings. It has no separate physician fee schedule payment.
Is 80074 the same as a hepatic function panel?
No. 80074 tests for viral hepatitis markers; a hepatic function panel measures liver-related analytes and does not provide this four-marker serology workup.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
Fee sheets
Put 80074 and the rest of your codes on one sheet
Your codes at your locality, with payer contracts beside Medicare.
Build my fee sheet