CPT code 80193: Drug assay, leflunomide measurement2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Laboratory measurement of leflunomide, reported when a laboratory performs testing to measure this medication for a patient.
Medicare pays $38.57 for 80193 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$38.57
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2021
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 80193 covers
Code 80193 reports a laboratory measurement of leflunomide. It identifies leflunomide as the analyte, distinguishing this service from assays that measure other medications, including mycophenolate, sirolimus, and tacrolimus. The code reports the leflunomide measurement performed by a clinical laboratory. It does not identify a measurement of those other analytes.
Medicare pays 80193 only through the CLFS. CMS sets one national amount per code, applicable in every state and locality, with no geographic adjustment or office-versus-facility difference. The 2026 national CLFS amount is $38.57, unchanged from 2021 through 2026. The physician fee schedule excludes the test by statute; Medicare payment is from the CLFS.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 80193
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 80193. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 80193 with status X (excluded by statute), so the test itself is paid only from the CLFS.
80193 on the lab fee schedule since 2021
80193 · CLFS 2026 Q4 (current)
$38.57
Unchanged since Jan 1, 2021
24 quarterly CLFS releases on file, first CLFS 2021 Q1. A code missing from a quarter wasn’t on that release.
80193 compared with similar tests
- 80180Mycophenolate levelQuantitative assay$18.05
- 80180 measures mycophenolate; 80193 measures leflunomide. Choose according to the medication measured.
- 80195Sirolimus levelWhole-blood drug level$13.73
- 80195 measures sirolimus, while 80193 measures leflunomide.
- 80197Drug levelTacrolimus concentration$13.73
- 80197 measures tacrolimus; use 80193 for the leflunomide measurement.
80193 billing questions
What does code 80193 measure?
It reports a laboratory measurement of leflunomide.
How do I distinguish 80193 from other drug assay codes?
Select 80193 for leflunomide. Codes such as 80180, 80195, and 80197 identify measurements of mycophenolate, sirolimus, and tacrolimus, respectively.
Does code 80193 identify a multi-drug panel?
No. It identifies measurement of leflunomide.
How does Medicare pay for code 80193?
Medicare pays it only under the CLFS, using one national amount per code across localities and office and facility settings.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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