CPT code 80200: Tobramycin level, antibiotic monitoring2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures tobramycin in a patient sample to monitor antibiotic exposure during treatment, including when clinicians assess dosing or potential drug toxicity.
Medicare pays $16.13 for 80200 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$16.13
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 80200 covers
This assay measures tobramycin, an aminoglycoside antibiotic, in a patient sample. Clinicians may order it during treatment of serious bacterial infections to help assess drug exposure, adjust dosing, or evaluate possible toxicity. Serum drug levels are commonly collected at times related to a dose, such as peak or trough sampling; the collection timing affects how the result is interpreted. Hospital and independent clinical laboratories typically perform and report the assay for the treating clinician.
Report 80200 for the tobramycin assay, not for another drug measured in the same monitoring episode. Medicare pays it only through the CLFS. The 2026 national CLFS amount is $16.13, unchanged from 2020 through 2026; one amount applies nationwide, without locality or office-versus-facility adjustment. The code is excluded from the physician fee schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 80200
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 80200. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 80200 with status X (excluded by statute), so the test itself is paid only from the CLFS.
80200 on the lab fee schedule since 2020
80200 · CLFS 2026 Q4 (current)
$16.13
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
80200 compared with similar tests
- 80202Vancomycin levelAntibiotic concentration$13.54
- Use 80202 for a vancomycin assay. Use 80200 when the measured antibiotic is tobramycin.
- 80201Topiramate levelTopiramate-specific assay$11.92
- Use 80201 for topiramate levels; 80200 is specific to tobramycin.
- 80299Drug assayUnlisted therapeutic drug$18.64
- 80299 is a general quantitative drug assay. Choose 80200 when the assay is specifically for tobramycin.
80200 billing questions
When should 80200 be selected instead of another drug assay?
Use 80200 when the measured drug is tobramycin. A different named drug, such as vancomycin or topiramate, has its own assay code.
Are peak and trough measurements reported with different codes?
No. Both measurements concern tobramycin; 80200 identifies the drug assay, not whether the sample is a peak or trough.
Does Medicare pay 80200 under the physician fee schedule?
No. Medicare pays this assay through the CLFS only.
Does Medicare pay a different amount by locality or setting?
No. The CLFS amount is national and applies across localities, with no office-versus-facility adjustment.
What should the laboratory documentation support?
Documentation should identify the tobramycin assay and support the clinical request, including relevant collection timing when interpreting a dose-related level.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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