CPT code 82085: Aldolase, enzyme level2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures aldolase in blood during evaluation of muscle weakness, muscle injury, or suspected inflammatory muscle disease.
Medicare pays $9.71 for 82085 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$9.71
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 82085 covers
Aldolase testing measures the level of this enzyme in a blood specimen, typically serum. Clinicians may order it when evaluating muscle weakness, suspected muscle injury, or inflammatory muscle disease. Laboratory personnel perform and report the assay in outpatient and other clinical settings, often alongside other enzyme tests used in a muscle evaluation.
Report 82085 for the aldolase assay. It is a laboratory test paid only under the Medicare Clinical Laboratory Fee Schedule (CLFS), not the physician fee schedule. The 2026 national CLFS amount is $9.71, unchanged since 2020. Medicare pays one amount per code nationwide, without locality adjustment or a difference between office and facility settings. Report the assay rather than treating the code as a panel or as an aldosterone test.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 82085
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 82085. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 82085 with status X (excluded by statute), so the test itself is paid only from the CLFS.
82085 on the lab fee schedule since 2020
82085 · CLFS 2026 Q4 (current)
$9.71
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
82085 compared with similar tests
- 82550Total CKTotal enzyme activity$6.51
- 82550 measures creatine kinase, a different enzyme commonly assessed in muscle evaluations. Use 82085 when aldolase is the test performed.
- 82088AldosteroneHormone level$40.75
- 82088 measures aldosterone, a hormone; 82085 measures the enzyme aldolase. Similar names do not indicate interchangeable tests.
- 84450ASTAspartate aminotransferase$5.18
- 84450 reports an AST assay. It is distinct from the aldolase enzyme assay reported with 82085.
82085 billing questions
When should 82085 be used instead of creatine kinase testing?
Use 82085 when the laboratory performs an aldolase assay. Creatine kinase testing measures a different enzyme and may be ordered alongside aldolase during evaluation of muscle symptoms.
Is aldolase the same test as aldosterone?
No. Aldolase is an enzyme measured under 82085; aldosterone is a hormone measured under 82088.
How is 82085 paid by Medicare?
Medicare pays 82085 under the CLFS. The payment is nationally set and does not vary by locality or office versus facility setting.
Does 82085 include a group of enzyme tests?
No. It reports the aldolase assay; other separately performed enzyme assays are reported under their own applicable codes.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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