CPT code 82233: Beta-amyloid, aβ40 peptide2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Laboratory testing measures beta-amyloid 1-40 (Aβ40), distinguishing this peptide-specific assay from testing for beta-amyloid 1-42 (Aβ42).
Medicare pays $128.92 for 82233 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$128.92
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2026
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 82233 covers
82233 identifies laboratory testing for beta-amyloid 1-40 (Aβ40), a specific beta-amyloid peptide. It is distinct from beta-amyloid 1-42 (Aβ42), identified by 82234, and from beta-2 protein testing, identified by 82232. The code choice follows the analyte tested: this code is for Aβ40, not Aβ42. For claim review, compare the billed code with the analyte named in the laboratory result; an Aβ42 result corresponds to the neighboring Aβ42 code, not 82233. These codes distinguish peptide-specific tests rather than interchangeable amyloid measurements.
Medicare pays 82233 under the Clinical Laboratory Fee Schedule (CLFS) only. CMS sets one national amount that applies in every state and locality, with no geographic adjustment or office-versus-facility payment difference. The 2026 national CLFS amount is $128.92. The test is excluded from physician fee schedule payment.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 82233
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 82233. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 82233 with status X (excluded by statute), so the test itself is paid only from the CLFS.
82233 on the lab fee schedule since 2025
82233 · CLFS 2026 Q4 (current)
$128.92
Unchanged since Jan 1, 2026
Every change on file
- Jan 1, 2026 · CLFS 2026 Q1MAC-priced → $128.92
8 quarterly CLFS releases on file, first CLFS 2025 Q1. A code missing from a quarter wasn’t on that release.
82233 compared with similar tests
82233 billing questions
How does 82233 differ from 82234?
82233 identifies testing for beta-amyloid 1-40 (Aβ40); 82234 identifies testing for beta-amyloid 1-42 (Aβ42). Choose the code that matches the analyte tested.
Can both codes be reported for one patient?
They identify different analytes. Each code corresponds to its respective peptide assay.
How does 82233 differ from 82232?
82233 identifies beta-amyloid 1-40 testing. 82232 identifies an assay of beta-2 protein.
How does Medicare pay for 82233?
Medicare pays 82233 through the CLFS at one national amount across states and localities, with no office-versus-facility payment difference.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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