CPT code 82677: Estriol, estriol hormone level2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures estriol in a laboratory specimen, commonly as a maternal serum screening marker during pregnancy when estriol is one of the requested analytes.
Medicare pays $24.18 for 82677 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$24.18
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 82677 covers
82677 reports a laboratory measurement of estriol, an estrogen hormone. Maternal serum estriol is commonly included as one analyte in prenatal serum screening; the ordering clinician considers it with other screening markers when assessing pregnancy-related risk. The laboratory reports the estriol result to the ordering clinician. This assay is distinct from testing for estradiol, estrone, total estrogens, or fractionated estrogens.
Report 82677 for the estriol assay, not as a code for an entire prenatal screening panel. Medicare pays it only through the Clinical Laboratory Fee Schedule (CLFS), at one national amount that applies across states and localities, with no office-versus-facility payment difference. The 2026 national CLFS amount is $24.18, unchanged since 2020. The test is excluded from the physician fee schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 82677
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 82677. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 82677 with status X (excluded by statute), so the test itself is paid only from the CLFS.
82677 on the lab fee schedule since 2020
82677 · CLFS 2026 Q4 (current)
$24.18
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
82677 compared with similar tests
- 82670EstradiolTotal estradiol$27.94
- 82677 measures estriol; 82670 is used when the laboratory measures estradiol.
- 82671Estrogen testFractionated$32.30
- 82677 identifies an estriol assay, while 82671 is for total estrogens.
- 82672Estrogen testTotal estrogen$21.70
- Use 82677 for estriol measurement and 82672 for fractionated estrogen testing.
- 82679EstroneEstrone-specific hormone assay$24.95
- 82677 measures estriol; 82679 measures estrone.
82677 billing questions
When should 82677 be reported instead of an estradiol assay?
Report 82677 when the laboratory measures estriol. Use 82670 when the requested analyte is estradiol.
Is 82677 the code for a complete prenatal screening panel?
No. It represents the estriol measurement, which may be one marker in maternal serum screening; it does not represent the entire screening panel.
How does Medicare pay for 82677?
Medicare pays 82677 through the CLFS at one national amount across localities, without an office-versus-facility payment difference.
Is 82677 paid through the physician fee schedule?
No. Medicare pays this test only through the CLFS; it is excluded from the physician fee schedule.
How does 82677 differ from 82671 and 82672?
82677 measures estriol, 82671 is for total estrogens, and 82672 is for fractionated estrogens. Select the code that matches the assay performed.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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