CPT code 83993: Calprotectin, stool protein level2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures calprotectin, a stool protein used as a marker of intestinal inflammation when clinicians evaluate or monitor inflammatory bowel disease.
Medicare pays $19.63 for 83993 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$19.63
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 83993 covers
This laboratory assay measures calprotectin, a protein, in a stool specimen. Clinicians use the result as a marker of intestinal inflammation when evaluating symptoms such as chronic diarrhea or abdominal pain and when assessing inflammatory bowel disease. Gastroenterology practices may order it to help distinguish an inflammatory bowel condition from a functional disorder or to follow disease activity. Clinical laboratories perform and report the assay.
Report 83993 for the fecal calprotectin assay. Medicare pays it only through the Clinical Laboratory Fee Schedule (CLFS). The 2026 national CLFS amount is $19.63, unchanged in each year from 2020 through 2026. The same national amount applies across states and localities, without an office-versus-facility difference. The test is excluded from the physician fee schedule, so no separate physician interpretation payment is made under that schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 83993
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 83993. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 83993 with status X (excluded by statute), so the test itself is paid only from the CLFS.
83993 on the lab fee schedule since 2020
83993 · CLFS 2026 Q4 (current)
$19.63
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
83993 compared with similar tests
- 83630Fecal lactoferrinQualitative$19.70
- Choose 83993 for a stool calprotectin assay and 83630 for fecal lactoferrin. Both assess inflammatory markers in stool, but they measure different proteins.
- 86140CRP testStandard CRP assay$5.18
- Code 86140 measures C-reactive protein, a systemic blood marker of inflammation. Code 83993 measures calprotectin in stool and reflects intestinal inflammation.
- 82274FIT stool testImmunoassay, 1–3 determinations$15.92
- Code 82274 is for fecal occult blood testing, not calprotectin. Select based on whether the ordered test detects blood or measures an inflammatory protein.
83993 billing questions
When should this code be chosen instead of fecal lactoferrin?
Use this code for a stool calprotectin assay. Fecal lactoferrin is a different inflammatory marker and is reported with 83630.
What does this assay measure?
It measures the level of calprotectin, a protein, in stool. Clinicians use it as a marker of intestinal inflammation.
Is a physician interpretation separately billable?
Medicare pays this test through the CLFS only. It is excluded from the physician fee schedule, so there is no separate physician interpretation payment under that schedule.
Does Medicare use a different amount by location or setting?
No. The CLFS amount is national and applies across localities, with no office-versus-facility difference.
Is this the same test as fecal occult blood testing?
No. Calprotectin measures a stool protein associated with intestinal inflammation; fecal occult blood testing looks for blood in stool.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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