CPT code 87339: H. pylori antigen, non-stool antigen assay2026 Medicare lab fee · Clinical Laboratory Fee Schedule
An immunoassay detects Helicobacter pylori antigen associated with the gastrointestinal tract when the reported service is not the stool-specific antigen test.
Medicare pays $16.00 for 87339 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$16.00
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 87339 covers
This laboratory test uses an immunoassay to detect H. pylori antigen associated with the gastrointestinal tract. The result is qualitative or semiquantitative. Clinicians may order H. pylori testing when evaluating suspected infection, including in patients with peptic ulcer disease. Code 87339 distinguishes the general antigen assay from the stool-specific H. pylori antigen service reported with 87338; the documented assay and specimen guide that distinction.
Report the antigen immunoassay performed, distinguishing it from stool antigen testing reported with 87338 and from antibody or breath testing. Medicare pays this code only through the Clinical Laboratory Fee Schedule (CLFS). The 2026 national CLFS amount is $16.00, unchanged since 2020. The same national amount applies in every locality, with no geographic or office-versus-facility adjustment. The test is paid only through the CLFS, not the physician fee schedule.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 87339
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 87339. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 87339 with status X (excluded by statute), so the test itself is paid only from the CLFS.
87339 on the lab fee schedule since 2020
87339 · CLFS 2026 Q4 (current)
$16.00
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
87339 compared with similar tests
- 87338H. pylori antigenStool immunoassay$14.38
- Use 87338 for the stool-specific H. pylori antigen test. Code 87339 describes general H. pylori antigen detection by immunoassay.
- 86677H. pylori antibodySerologic testing$16.85
- Code 86677 is for H. pylori antibody testing; 87339 detects H. pylori antigen.
- 83013H. pylori Breath TestCarbon-13 urease analysis$67.36
- Code 83013 reports H. pylori breath-test analysis. Use 87339 for antigen detection by immunoassay, not breath testing.
87339 billing questions
How does 87339 differ from 87338?
87338 is the stool-specific H. pylori antigen test. Use 87339 for the general H. pylori antigen immunoassay when the documented service is not the stool-specific test.
Is 87339 an H. pylori antibody test?
No. It reports qualitative or semiquantitative antigen detection by immunoassay. H. pylori antibody testing is a different service, such as code 86677.
Can 87339 be reported for a breath test?
No. This code reports antigen detection by immunoassay; a breath test uses a different method and code.
Does Medicare pay 87339 under the physician fee schedule?
No. Medicare pays this test through the CLFS, at one national amount across localities and settings.
What should the documentation distinguish from 87338?
Document the assay and specimen so the general H. pylori antigen service can be distinguished from the stool-specific antigen test.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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