CPT code 87341: HBsAg confirmation, neutralization assay2026 Medicare lab fee · Clinical Laboratory Fee Schedule
This immunoassay uses neutralization to confirm hepatitis B surface antigen detection after a reactive HBsAg screen.
Medicare pays $10.33 for 87341 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$10.33
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 8 sections
What 87341 covers
This immunoassay uses a neutralization step to determine whether a detected hepatitis B surface antigen (HBsAg) signal is specific to HBsAg. It is used as confirmation following a reactive HBsAg screening immunoassay; 87340 identifies the initial HBsAg immunoassay. Clinical laboratories perform and report the assay as part of hepatitis B testing. It addresses surface antigen, not hepatitis B surface antibody or core antibody, which are different markers.
Report 87341 for the neutralization test when performed and 87340 for the initial HBsAg immunoassay when that test is also performed. Medicare pays 87341 through the CLFS at one national amount across states and localities, with no office or facility difference. The 2026 national CLFS amount is $10.33, unchanged since 2020. The test is excluded from the physician fee schedule by statute.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 87341
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 87341. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 87341 with status X (excluded by statute), so the test itself is paid only from the CLFS.
87341 on the lab fee schedule since 2020
87341 · CLFS 2026 Q4 (current)
$10.33
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
87341 compared with similar tests
- 87340HBsAg testSurface antigen immunoassay$10.33
- 87340 identifies the initial HBsAg immunoassay. 87341 is the neutralization test used to confirm a reactive HBsAg result.
- 87350HBeAg testImmunoassay antigen detection$11.53
- 87350 tests for hepatitis B e antigen, not surface antigen. 87341 is used for HBsAg neutralization.
- 86706Surface antibodyHepatitis B$10.74
- 86706 measures hepatitis B surface antibody, a different marker from the surface antigen addressed by 87341.
- 86704Core antibodyTotal antibody$12.05
- 86704 measures hepatitis B core antibody; 87341 is for neutralization of a detected HBsAg signal.
87341 billing questions
When is 87341 reported?
Report it for the HBsAg neutralization test used to confirm a reactive HBsAg screening result.
Can 87341 be reported with 87340?
Yes, when both the initial HBsAg immunoassay and the neutralization test are performed. The codes identify distinct tests.
How does 87341 differ from 87350?
87341 is for HBsAg neutralization; 87350 tests for hepatitis B e antigen.
How does Medicare pay for 87341?
Medicare pays it through the CLFS at one national amount across localities, with no office or facility difference. It is excluded from the physician fee schedule.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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