CPT code 87507: GI pathogen panel, 12–25 targets2026 Medicare lab fee · Clinical Laboratory Fee Schedule

Reports a multiplex nucleic acid test for detecting 12–25 gastrointestinal pathogen targets, commonly used to investigate infectious diarrhea.

CMS CLFS 2026 Q4Effective Oct 1, 2026Same amount nationwide14.4K Medicare services in 2024

Medicare pays $416.78 for 87507 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.

Medicare lab fee · CLFS 2026 Q4

National CLFS amount

$416.78

In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.

Geographic adjustment
None
Office vs facility
Same
Since 2020
Unchanged
CMS updates
Quarterly

Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.

On this page 8 sections
  1. Medicare lab fee
  2. What 87507 covers
  3. How it’s paid
  4. Amount history
  5. Similar tests
  6. Related codes
  7. Billing questions
  8. Sources

What 87507 covers

This laboratory test uses multiplex nucleic acid methods to detect a broad range of gastrointestinal pathogens, such as C. difficile, pathogenic E. coli, Salmonella, Shigella, norovirus, and Giardia. It is commonly performed on stool from patients being evaluated for infectious diarrhea. Clinical laboratories and hospital laboratories typically perform and report the test; the panel is useful when the clinical question calls for testing across multiple possible infectious causes rather than a single-organism assay.

Report one unit for the panel performed on a specimen, not separate units for each target detected. Select this code for a panel covering 12–25 targets; panels with fewer targets have separate codes. Medicare pays the test only through the CLFS. The 2026 national CLFS amount is $416.78, unchanged since 2020, and the same amount applies across localities and office or facility settings. The test is excluded from the physician fee schedule.

This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.

How Medicare pays 87507

Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.

One national amount

CMS sets a single Clinical Laboratory Fee Schedule amount for 87507. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.

No office or facility rate

Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.

Updated every quarter

CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.

Excluded from the physician fee schedule

The physician fee schedule lists 87507 with status X (excluded by statute), so the test itself is paid only from the CLFS.

87507 on the lab fee schedule since 2020

87507 · CLFS 2026 Q4 (current)

$416.78

Unchanged since Jan 1, 2020

Amount in each year’s latest CLFS release · bars start at $0

27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.

87507 compared with similar tests

87505GI pathogen panelThree to five targets$128.29
87505 is for a gastrointestinal pathogen panel with fewer targets. Use 87507 when the panel covers 12–25 targets.
87506GI pathogen panel6–11 targets$262.99
87506 covers a smaller gastrointestinal panel target range, 6–11 targets; 87507 applies to panels with 12–25 targets.
87493C. difficile testToxin-gene amplification$37.27
87493 is a C. difficile-specific molecular test. Use 87507 for a broad gastrointestinal pathogen panel covering 12–25 targets.

87507 billing questions

When should this code be selected instead of 87506?

Use 87507 when the gastrointestinal panel covers 12–25 targets. Code 87506 is the related panel code for a smaller target range.

Are individual pathogens reported separately from the panel?

This code represents the multiplex panel, not a separate charge for each organism target. Report the panel test performed.

How many units should be reported?

Report one unit for each panel test performed on a specimen, rather than one unit per target.

How does Medicare pay for this test?

Medicare pays it through the CLFS only, at one national amount that applies across localities and office or facility settings.

How does this differ from a C. difficile-only molecular test?

This code represents a broad gastrointestinal panel with 12–25 targets. A C. difficile-specific molecular test, such as 87493, addresses that organism rather than a broad panel.

Where this amount comes from

FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.

CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file line behind this amount
CLFS row for 87507PUF_CLFS_CY2026_Q4V1.csv, line 2,015 (CLFS 2026 Q4)

Open CMS sourceHow we source rates

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