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CPT code 88189: Flow cytometry, 16 or more markers2026 Medicare rate & RVUs in Detroit, MI

Reports the professional interpretation of a flow cytometry study using 16 or more markers, commonly for immunophenotyping blood, marrow, tissue, or fluid specimens.

CMS RVU26DEffective Oct 1, 2026One payment locality265.5K Medicare services in 2024

In Detroit, MI, Medicare pays $80.02 for 88189 in the office and $80.02 when it’s performed in a hospital or facility.

$80.02Office (non-facility)
$80.02Hospital or facility
+1.1%vs the national office rate ($79.16)

Check a contract rate as a % of Medicare · 88189 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88189 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Detroit, MI
  2. What 88189 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88189 covers

A pathologist or other qualified physician interprets flow cytometry findings from a study using 16 or more markers and prepares the interpretive report. These studies commonly support evaluation of suspected hematologic malignancies, such as leukemia or lymphoma, using specimens such as peripheral blood, bone marrow, lymph node tissue, or body fluids. The interpretation assesses the marker findings as a whole rather than billing for the laboratory work that processes and analyzes the specimen.

Select this level according to the number of markers in the study: 88189 is for 16 or more, while 88187 and 88188 cover lower marker ranges. The record should support the marker count and include the signed interpretation and report. This is a professional-component-only code; separate code or codes cover the technical portion. The technical services may include 88184 for the first marker and 88185 for additional markers, as appropriate.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Detroit, MI compares for 88189

Across 109 of 109 payment localities, the office rate for 88189 runs from $75.01 in Arkansas to $107.22 in Alaska. Detroit, MI pays $80.02. The RVUs are the same everywhere; the geographic indexes change the dollars.

88189 in Detroit, MI vs other payment areas
  1. Detroit, MI · this page$80.02
  2. Rest of Michigan · Michigan$77.60−$2.42
  3. Los Angeles, CA · California$84.56+$4.54
  4. Washington, DC area · District of Columbia$86.22+$6.20
  5. Miami, FL · Florida$83.61+$3.59
  6. Chicago, IL · Illinois$82.68+$2.66
  7. Manhattan, NY · New York$87.54+$7.52

Other areas in Michigan first, then benchmark localities. Bars start at $0.

Every other payment area

88189 in every other Medicare payment locality
Payment localityOfficeFacility
AlaskaAlaska$107.22$107.22
AlabamaAlabama$75.47$75.47
ArkansasArkansas$75.01$75.01
ArizonaArizona$78.16$78.16
Bakersfield, CACalifornia$81.35$81.35
Chico, CACalifornia$81.07$81.07
El Centro, CACalifornia$81.08$81.08
Fresno, CACalifornia$81.07$81.07

88189 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$75.01

$107.22

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88189 office rate range by state
State / territoryOffice rate rangeLocalities
AK$107.221
AL$75.471
AR$75.011
AZ$78.161
CA$81.07–$93.6229
CO$80.681
CT$82.411
DC$86.221
DE$78.941
FL$79.40–$83.613
GA$77.30–$80.142
GU$81.101
HI$81.101
IA$75.931
ID$76.221
IL$78.62–$82.684
IN$76.401
KS$75.951
KY$76.591
LA$76.60–$78.222
MA$80.71–$85.322
MD$79.78–$86.223
ME$76.57–$78.102
MI$77.60–$80.022
MN$78.131
MO$76.15–$78.143
MS$75.581
MT$79.161
NC$76.881
ND$77.771
NE$76.061
NH$79.741
NJ$83.57–$86.232
NM$77.861
NV$78.791
NY$77.40–$88.755
OH$77.321
OK$76.351
OR$78.38–$81.822
PA$77.28–$81.492
PR$79.361
RI$80.671
SC$77.181
SD$77.611
TN$76.131
TX$77.07–$80.338
UT$77.641
VA$78.11–$86.222
VI$79.361
VT$77.791
WA$80.46–$86.362
WI$76.641
WV$77.371
WY$78.551

See 88189 in every payment locality

How the 88189 rate is calculated

Each of 88189’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88189

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.66

1.66 RVUs× 1.000 GPCI

Practice expense0.64

0.64 RVUs× 1.000 GPCI

Malpractice0.07

0.07 RVUs× 1.000 GPCI

Adjusted RVUs

2.3700

Conversion factor

$33.4009

Medicare rate

$79.16

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Detroit, MI inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,166

Code
88189
Physician work
1.66
Practice expense
0.64
Malpractice
0.07

GPCI2026.csv

64

Locality
Detroit, MI
Physician work
1.000
Practice expense
0.965
Malpractice
1.686
Office calculation for 88189 in Detroit, MI
ComponentRVULocality factorAdjusted
Physician work1.66× 1.0001.6600
Practice expense0.64× 0.9650.6176
Malpractice0.07× 1.6860.1180
Total RVUs2.3956
Conversion factor× 33.4009

Office rate, Detroit, MI$80.02

Office: (1.66 × 1 + 0.64 × 0.965 + 0.07 × 1.686) × $33.4009 = $80.02

Facility: (1.66 × 1 + 0.64 × 0.965 + 0.07 × 1.686) × $33.4009 = $80.02

Open 88189 in the RVU calculator

Payment rules and modifiers for 88189

The CMS indicators that decide how 88189 is paid alongside other services.

CMS payment indicators · 88189

Flow cytometry, 16 or more markers

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical2Professional component only.

Codes related to 88189

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 88189
CodeHow it relatesOffice range, Detroit, MI
Same family
88187Flow cytometry, 2–8 marker interpretationProfessional interpretation for a flow cytometry study using a lower marker range.$35.41
88188Flow cytometry, 9–15 markersProfessional interpretation for 9 through 15 markers; 88189 begins at 16.$59.22
Often billed with
88184Flow cytometry, first marker, technical componentMay report the technical portion for the study's first marker.$78.81
88185Flow cytometry add-on, technical work, each additional markerMay report technical work for additional markers.$22.24

How 88189 has changed in Detroit, MI

88189 · Office / nonfacility

$80.02

Effective 2026-10-01

The base rate is $0.71 lower than on 2025-10-01, moving from $80.73 to $80.02 (0.9%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $80.73changed to$80.02

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.70 changed to 1.66
    • Practice expense RVU 0.68 changed to 0.64
    • Work GPCI 1.003 changed to 1.000
    • Practice expense GPCI 0.986 changed to 0.965
    • Malpractice GPCI 1.718 changed to 1.686

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $83.32changed to$80.73

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 0.67 changed to 0.68
    • Malpractice RVU 0.08 changed to 0.07

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $81.96changed to$83.32

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $84.99changed to$81.96

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.68 changed to 0.67
    • Work GPCI 1.000 changed to 1.003
    • Practice expense GPCI 0.992 changed to 0.986
    • Malpractice GPCI 1.670 changed to 1.718

  5. January 1, 2023

    RVU23A

    $86.31changed to$84.99

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.65 changed to 0.68
    • Malpractice RVU 0.09 changed to 0.08
    • Practice expense GPCI 0.997 changed to 0.992
    • Malpractice GPCI 1.622 changed to 1.670

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $87.02changed to$86.31

    • Conversion factor 34.8931 changed to 34.6062

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $90.75changed to$87.02

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 0.67 changed to 0.65
    • Practice expense GPCI 0.993 changed to 0.997
    • Malpractice GPCI 1.657 changed to 1.622

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $90.02changed to$90.75

    • Conversion factor 36.0391 changed to 36.0896
    • Malpractice RVU 0.08 changed to 0.09
    • Practice expense GPCI 0.989 changed to 0.993
    • Malpractice GPCI 1.691 changed to 1.657

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $90.64changed to$90.02

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.69 changed to 0.67

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $93.83changed to$90.64

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 0.80 changed to 0.69
    • Practice expense GPCI 0.992 changed to 0.989
    • Malpractice GPCI 1.510 changed to 1.691

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $115.21changed to$93.83

    • Conversion factor 35.8043 changed to 35.8887
    • Work RVU 2.23 changed to 1.70
    • Practice expense RVU 0.86 changed to 0.80
    • Malpractice RVU 0.10 changed to 0.08
    • Practice expense GPCI 0.994 changed to 0.992
    • Malpractice GPCI 1.328 changed to 1.510

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $114.91changed to$115.21

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 0.84 changed to 0.86

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $114.33changed to$114.91

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $113.98changed to$114.33

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 0.75 changed to 0.84
    • Malpractice RVU 0.11 changed to 0.10
    • Work GPCI 1.010 changed to 1.000
    • Practice expense GPCI 1.009 changed to 0.994
    • Malpractice GPCI 1.571 changed to 1.328

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $112.09changed to$113.98

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 0.78 changed to 0.75
    • Malpractice RVU 0.12 changed to 0.11
    • Work GPCI 1.022 changed to 1.010
    • Practice expense GPCI 1.023 changed to 1.009
    • Malpractice GPCI 1.814 changed to 1.571

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $112.09

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$80.02$80.02RVU26D
2026-07-01$80.02$80.02RVU26C
2026-04-01$80.02$80.02RVU26B
2026-01-01$80.02$80.02RVU26A
2025-10-01$80.73$80.73RVU25D
2025-07-01$80.73$80.73RVU25C
2025-04-01$80.73$80.73RVU25B
2025-01-01$80.73$80.73RVU25A
2024-10-01$83.32$83.32RVU24D
2024-07-01$83.32$83.32RVU24C
2024-04-01$83.32$83.32RVU24B
2024-03-09$83.32$83.32RVU24AR
2024-01-01$81.96$81.96RVU24A
2023-10-01$84.99$84.99RVU23D
2023-07-01$84.99$84.99RVU23C
2023-04-01$84.99$84.99RVU23B
2023-01-01$84.99$84.99RVU23A
2022-10-01$86.31$86.31RVU22D
2022-07-01$86.31$86.31RVU22C
2022-04-01$86.31$86.31RVU22B
2022-01-01$86.31$86.31RVU22A
2021-10-01$87.02$87.02RVU21D
2021-07-01$87.02$87.02RVU21C
2021-04-01$87.02$87.02RVU21B
2021-01-01$87.02$87.02RVU21A
2020-10-01$90.75$90.75RVU20D
2020-07-01$90.75$90.75RVU20C
2020-04-01$90.75$90.75RVU20B
2020-01-01$90.75$90.75RVU20A
2019-10-01$90.02$90.02RVU19D
2019-07-01$90.02$90.02RVU19C
2019-04-01$90.02$90.02RVU19B
2019-01-01$90.02$90.02RVU19A
2018-10-01$90.64$90.64RVU18D
2018-07-01$90.64$90.64RVU18C
2018-04-01$90.64$90.64RVU18B
2018-01-01$90.64$90.64RVU18AR1
2017-10-01$93.83$93.83RVU17D
2017-07-01$93.83$93.83RVU17C
2017-04-01$93.83$93.83RVU17B
2017-01-01$93.83$93.83RVU17A
2016-10-01$115.21$115.21RVU16D
2016-07-01$115.21$115.21RVU16C
2016-04-01$115.21$115.21RVU16B
2016-01-01$115.21$115.21RVU16A
2015-10-01$114.91$114.91RVU15D
2015-07-01$114.91$114.91RVU15C
2015-04-01$114.33$114.33RVU15B
2015-01-01$114.33$114.33RVU15A
2014-10-01$113.98$113.98RVU14D
2014-07-01$113.98$113.98RVU14C
2014-04-01$113.98$113.98RVU14B
2014-01-01$113.98$113.98RVU14A
2013-10-01$112.09$112.09RVU13D
2013-07-01$112.09$112.09RVU13C
2013-04-01$112.09$112.09RVU13B
2013-01-01$112.09$112.09RVU13AR

Price 88189 for an earlier date of service

Where the Detroit, MI rate applies

Detroit, MI is a Medicare payment area, not a city. Our Census mapping connects it to 98 cities and communities in Michigan. Some span more than one payment area; confirm with the service ZIP.

  • Detroit
  • Allen Park
  • Ann Arbor
  • Armada
  • Auburn Hills
  • Barton Hills
  • Belleville
  • Berkley

Browse all communities in Michigan

88189 billing questions

When should 88189 be selected instead of 88188?

Use 88189 when the flow cytometry study includes 16 or more markers. Code 88188 is for the lower range of 9 through 15 markers.

Does 88189 include the laboratory's technical work?

No. It represents the professional interpretation and report; separate code or codes cover the technical portion.

Which codes may represent the technical portion?

Code 88184 covers the technical work for the first marker, and 88185 covers additional markers, as appropriate to the study.

What documentation supports reporting 88189?

Keep the flow cytometry report, the marker count supporting the 16-or-more level, and the signed professional interpretation.

Should modifier 26 be appended to 88189?

No. 88189 is already a professional-component-only code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88189PPRRVU2026_Oct_nonQPP.csv, line 11,166 (RVU26D)
Geographic factors for Detroit, MIGPCI2026.csv, line 64 (RVU26D)

Open CMS sourceHow we calculate rates

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