CPT code 88313: Special stain, group II, tissue constituents2026 Medicare rate & RVUs in Napa, CA

Group II histochemical staining highlights tissue features such as fibrosis, iron, or amyloid and is reported once per stain per specimen.

CMS RVU26DEffective Oct 1, 2026One payment locality1.4M Medicare services in 2024

In Napa, CA, Medicare pays $104.03 for 88313 in the office.

$104.03Office (non-facility)
Not available in this settingHospital or facility
+28.7%vs the national office rate ($80.83)

Check a contract rate as a % of Medicare · 88313 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88313 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Napa, CA
  2. What 88313 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88313 covers

Group II histochemical stains highlight tissue components rather than infectious organisms. Examples include trichrome for fibrosis, Prussian blue for iron, reticulin for tissue architecture, elastic stains for vessel walls, and Congo red for amyloid. Histology staff prepare and stain slides, commonly from paraffin blocks, and a pathologist interprets the findings in the pathology report. These stains may be used on liver biopsies to assess fibrosis or iron, medical kidney biopsies to examine tissue architecture, and cardiac or fat pad biopsies to investigate amyloid.

Report one unit for each distinct Group II stain on each specimen, generally with the applicable tissue examination code, such as 88305 or 88307. The report should identify the specimen, stain, and result. Stains used to identify microorganisms belong in 88312; frozen-section histochemistry and enzyme histochemistry have separate codes. CMS prices the professional interpretation with modifier 26 and the technical preparation, reagents, and staff work with modifier TC. Billing without either modifier represents the global service. Physician work accounts for about 10% of the office total.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Napa, CA compares for 88313

Across 109 of 109 payment localities, the office rate for 88313 runs from $70.29 in Arkansas to $113.40 in San Benito County, CA. Napa, CA pays $104.03. The RVUs are the same everywhere; the geographic indexes change the dollars.

88313 in Napa, CA vs other payment areas
  1. Napa, CA · this page$104.03
  2. Bakersfield, CA · California$87.67−$16.36
  3. Chico, CA · California$87.61−$16.42
  4. El Centro, CA · California$87.61−$16.42
  5. Fresno, CA · California$87.61−$16.42
  6. Hanford, CA · California$87.61−$16.42
  7. Los Angeles, CA · California$94.18−$9.85

Other areas in California first, then benchmark localities. Bars start at $0.

Every other payment area

88313 in every other Medicare payment locality
Payment localityOfficeFacility
Madera, CACalifornia$87.61—
Merced, CACalifornia$87.61—
Modesto, CACalifornia$87.61—
Oxnard, CACalifornia$93.98—
Redding, CACalifornia$87.61—
Rest of CaliforniaCalifornia$87.61—
Riverside, CACalifornia$87.83—
Sacramento, CACalifornia$92.61—

88313 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$70.29

$100.51

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88313 office rate range by state
State / territoryOffice rate rangeLocalities
AK$89.081
AL$71.481
AR$70.291
AZ$78.491
CA$87.61–$113.4029
CO$85.411
CT$86.711
DC$94.221
DE$79.931
FL$77.98–$84.823
GA$73.13–$82.152
GU$90.481
HI$90.481
IA$74.271
ID$74.681
IL$74.90–$83.364
IN$75.201
KS$73.541
KY$72.731
LA$72.47–$76.642
MA$84.66–$95.132
MD$81.72–$94.223
ME$74.78–$79.932
MI$74.61–$78.752
MN$82.461
MO$70.81–$77.353
MS$70.581
MT$80.831
NC$75.731
ND$80.431
NE$74.831
NH$83.721
NJ$87.87–$92.962
NM$74.951
NV$80.791
NY$77.01–$95.595
OH$74.531
OK$72.931
OR$80.34–$88.832
PA$74.85–$84.072
PR$81.621
RI$83.301
SC$75.221
SD$80.391
TN$73.931
TX$74.26–$84.978
UT$76.411
VA$79.40–$94.222
VI$81.621
VT$79.781
WA$84.61–$97.542
WI$77.321
WV$71.621
WY$80.661

See 88313 in every payment locality

How the 88313 rate is calculated

Each of 88313’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88313

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.23

0.23 RVUs× 1.000 GPCI

Practice expense2.17

2.17 RVUs× 1.000 GPCI

Malpractice0.02

0.02 RVUs× 1.000 GPCI

Adjusted RVUs

2.4200

Conversion factor

$33.4009

Medicare rate

$80.83

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Napa, CA inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,221

Code
88313
Physician work
0.23
Practice expense
2.17
Malpractice
0.02

GPCI2026.csv

17

Locality
Napa, CA
Physician work
1.063
Practice expense
1.318
Malpractice
0.508
Office calculation for 88313 in Napa, CA
ComponentRVULocality factorAdjusted
Physician work0.23× 1.0630.2445
Practice expense2.17× 1.3182.8601
Malpractice0.02× 0.5080.0102
Total RVUs3.1147
Conversion factor× 33.4009

Office rate, Napa, CA$104.03

Office: (0.23 × 1.063 + 2.17 × 1.318 + 0.02 × 0.508) × $33.4009 = $104.03

Open 88313 in the RVU calculator

Payment rules and modifiers for 88313

The CMS indicators that decide how 88313 is paid alongside other services.

CMS payment indicators · 88313

Special stain, group II, tissue constituents

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88313 without 26 · national office

$80.83

Special stain, group II, tissue constituents

88313-26 · Professional component

$11.36

Pays only the interpretation and report.

When to use modifier 26

How 88313 has changed in Napa, CA

88313 · Office / nonfacility

$104.03

Effective 2026-10-01

The base rate is $2.26 higher than on 2025-10-01, moving from $101.77 to $104.03 (2.2%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $101.77changed to$104.03

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.24 changed to 0.23
    • Practice expense RVU 2.20 changed to 2.17
    • Work GPCI 1.058 changed to 1.063
    • Practice expense GPCI 1.310 changed to 1.318
    • Malpractice GPCI 0.521 changed to 0.508

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $106.04changed to$101.77

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 2.23 changed to 2.20

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $104.31changed to$106.04

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $102.35changed to$104.31

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 2.18 changed to 2.23
    • Work GPCI 1.051 changed to 1.058
    • Practice expense GPCI 1.265 changed to 1.310
    • Malpractice GPCI 0.513 changed to 0.521
  5. January 1, 2023

    RVU23A

    $98.53changed to$102.35

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 2.12 changed to 2.18
    • Work GPCI 1.044 changed to 1.051
    • Practice expense GPCI 1.220 changed to 1.265
    • Malpractice GPCI 0.504 changed to 0.513

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $97.64changed to$98.53

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 2.08 changed to 2.12

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $93.44changed to$97.64

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.88 changed to 2.08
    • Work GPCI 1.049 changed to 1.044
    • Practice expense GPCI 1.238 changed to 1.220
    • Malpractice GPCI 0.496 changed to 0.504

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $90.48changed to$93.44

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 1.79 changed to 1.88
    • Work GPCI 1.055 changed to 1.049
    • Practice expense GPCI 1.256 changed to 1.238
    • Malpractice GPCI 0.458 changed to 0.496

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $88.12changed to$90.48

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.74 changed to 1.79

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $87.45changed to$88.12

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 1.71 changed to 1.74
    • Work GPCI 1.057 changed to 1.055
    • Practice expense GPCI 1.271 changed to 1.256
    • Malpractice GPCI 0.477 changed to 0.458

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    No ratechanged to$87.45

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$104.03Not available in this settingRVU26D
2026-07-01$104.03Not available in this settingRVU26C
2026-04-01$104.03Not available in this settingRVU26B
2026-01-01$104.03Not available in this settingRVU26A
2025-10-01$101.77Not available in this settingRVU25D
2025-07-01$101.77Not available in this settingRVU25C
2025-04-01$101.77Not available in this settingRVU25B
2025-01-01$101.77Not available in this settingRVU25A
2024-10-01$106.04Not available in this settingRVU24D
2024-07-01$106.04Not available in this settingRVU24C
2024-04-01$106.04Not available in this settingRVU24B
2024-03-09$106.04Not available in this settingRVU24AR
2024-01-01$104.31Not available in this settingRVU24A
2023-10-01$102.35Not available in this settingRVU23D
2023-07-01$102.35Not available in this settingRVU23C
2023-04-01$102.35Not available in this settingRVU23B
2023-01-01$102.35Not available in this settingRVU23A
2022-10-01$98.53Not available in this settingRVU22D
2022-07-01$98.53Not available in this settingRVU22C
2022-04-01$98.53Not available in this settingRVU22B
2022-01-01$98.53Not available in this settingRVU22A
2021-10-01$97.64Not available in this settingRVU21D
2021-07-01$97.64Not available in this settingRVU21C
2021-04-01$97.64Not available in this settingRVU21B
2021-01-01$97.64Not available in this settingRVU21A
2020-10-01$93.44Not available in this settingRVU20D
2020-07-01$93.44Not available in this settingRVU20C
2020-04-01$93.44Not available in this settingRVU20B
2020-01-01$93.44Not available in this settingRVU20A
2019-10-01$90.48Not available in this settingRVU19D
2019-07-01$90.48Not available in this settingRVU19C
2019-04-01$90.48Not available in this settingRVU19B
2019-01-01$90.48Not available in this settingRVU19A
2018-10-01$88.12Not available in this settingRVU18D
2018-07-01$88.12Not available in this settingRVU18C
2018-04-01$88.12Not available in this settingRVU18B
2018-01-01$88.12Not available in this settingRVU18AR1
2017-10-01$87.45Not available in this settingRVU17D
2017-07-01$87.45Not available in this settingRVU17C
2017-04-01$87.45Not available in this settingRVU17B
2017-01-01$87.45Not available in this settingRVU17A
2016-10-01Rate data unavailableNot available in this settingRVU16D
2016-07-01Rate data unavailableNot available in this settingRVU16C
2016-04-01Rate data unavailableNot available in this settingRVU16B
2016-01-01Rate data unavailableNot available in this settingRVU16A
2015-10-01Rate data unavailableNot available in this settingRVU15D
2015-07-01Rate data unavailableNot available in this settingRVU15C
2015-04-01Rate data unavailableNot available in this settingRVU15B
2015-01-01Rate data unavailableNot available in this settingRVU15A
2014-10-01Rate data unavailableNot available in this settingRVU14D
2014-07-01Rate data unavailableNot available in this settingRVU14C
2014-04-01Rate data unavailableNot available in this settingRVU14B
2014-01-01Rate data unavailableNot available in this settingRVU14A
2013-10-01Rate data unavailableNot available in this settingRVU13D
2013-07-01Rate data unavailableNot available in this settingRVU13C
2013-04-01Rate data unavailableNot available in this settingRVU13B
2013-01-01Rate data unavailableNot available in this settingRVU13AR

Price 88313 for an earlier date of service

Where the Napa, CA rate applies

Napa, CA is a Medicare payment area, not a city. Our Census mapping connects it to 11 cities and communities in California. Some span more than one payment area; confirm with the service ZIP.

  • Napa
  • American Canyon
  • Angwin
  • Calistoga
  • Deer Park
  • Moskowite Corner
  • Oakville
  • Rutherford

Browse all communities in California

88313 billing questions

How many units are reported when several Group II stains are performed?

Report one unit per distinct stain per specimen. A liver biopsy with trichrome and iron stains supports two units; the same stain on two separately submitted specimens also supports two units.

When is 88312 used instead of 88313?

Use 88312 for a stain performed to identify microorganisms, such as a fungal, acid-fast, or Gram stain. Use 88313 for stains demonstrating tissue constituents such as collagen, iron, glycogen, elastic fibers, or amyloid.

Does the stain's purpose matter if the same stain can serve either group?

Yes. A PAS stain used to look for fungi is reported with 88312, while PAS used to evaluate glycogen or basement membranes is reported with 88313.

Is the routine H&E slide separately reportable with 88313?

No. Routine H&E staining is included in the gross and microscopic surgical pathology examination. Report 88313 for a separately performed Group II special stain.

How are modifiers 26 and TC applied?

A pathologist who interprets a slide stained by another entity bills 88313 with modifier 26. The entity providing only slide preparation and staining bills with modifier TC; an entity providing both components bills without either modifier.

What documentation supports each unit?

The pathology report should identify each stain and specimen and describe the result or its diagnostic significance. An order without a reported interpretation does not support billing the professional component.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88313PPRRVU2026_Oct_nonQPP.csv, line 11,221 (RVU26D)
Geographic factors for Napa, CAGPCI2026.csv, line 17 (RVU26D)

Open CMS sourceHow we calculate rates

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