CPT code 89325: Sperm antibody2026 Medicare lab fee · Clinical Laboratory Fee Schedule
Measures antibodies directed against sperm during infertility evaluation when clinicians are considering a possible immune contribution.
Medicare pays $10.67 for 89325 under the 2026 Clinical Laboratory Fee Schedule: one national amount, the same in every state and setting.
Medicare lab fee · CLFS 2026 Q4
National CLFS amount
$10.67
In effect since Jan 1, 2026. The same amount in every state, payment locality and setting.
- Geographic adjustment
- None
- Office vs facility
- Same
- Since 2020
- Unchanged
- CMS updates
- Quarterly
Medicare pays the lesser of the lab’s charge and this amount. Patients usually owe no Part B deductible or coinsurance for covered clinical lab tests.
On this page 7 sections
What 89325 covers
This laboratory test measures antibodies directed against sperm. Clinicians may request it during an infertility evaluation when an immune factor is considered. The result addresses antibody findings; it is distinct from semen measurements such as volume, count, and motility and from testing that detects sperm presence. Reproductive laboratories report the measurement for the ordering clinician.
Report 89325 for the sperm-antibody measurement performed. Medicare pays it only under the CLFS, at one national amount applicable across all states and localities without geographic or office/facility adjustment. The 2026 national amount is $10.67 and remained unchanged from 2020 through 2025. The physician fee schedule excludes this test by statute; Medicare payment is through CLFS rather than PFS.
This summary was written with AI assistance from CMS Clinical Laboratory Fee Schedule data. Amounts on this page come directly from CMS files.
How Medicare pays 89325
Clinical lab tests aren’t priced like physician services. They’re paid from their own fee schedule, with its own rules. See the whole lab fee schedule.
One national amount
CMS sets a single Clinical Laboratory Fee Schedule amount for 89325. There’s no geographic (GPCI) adjustment, so it pays the same in every state and payment locality.
No office or facility rate
Lab tests aren’t built from relative value units, so there’s no office and facility split: the place of service doesn’t change the CLFS amount.
Updated every quarter
CMS republishes the CLFS each quarter. New tests, often proprietary laboratory analyses (PLA codes), join during the year; existing amounts are updated each January.
Excluded from the physician fee schedule
The physician fee schedule lists 89325 with status X (excluded by statute), so the test itself is paid only from the CLFS.
89325 on the lab fee schedule since 2020
89325 · CLFS 2026 Q4 (current)
$10.67
Unchanged since Jan 1, 2020
27 quarterly CLFS releases on file, first CLFS 2020 Q1. A code missing from a quarter wasn’t on that release.
89325 compared with similar tests
- 89310Semen analysisMotility and count$8.61
- Choose 89325 for measurement of sperm-directed antibodies. Code 89310 concerns semen analysis that includes sperm count.
- 89320Semen analysisVolume, count, motility, differential$12.31
- Code 89320 evaluates semen volume, count, and motility; 89325 measures sperm-directed antibodies.
- 89321Semen analysisSperm presence and motility$12.05
- Code 89321 is for sperm detection in semen testing, while 89325 measures antibodies directed against sperm.
- 89300Semen analysisIncludes postcoital testing$9.84
- Code 89300 combines semen evaluation with a postcoital assessment. Code 89325 measures sperm antibodies.
89325 billing questions
How does 89325 differ from a semen analysis?
89325 measures antibodies directed against sperm. Semen-analysis codes describe other evaluations, such as sperm count, motility, or sperm detection.
Does 89325 include a semen analysis?
89325 identifies the sperm-antibody measurement, not semen volume, count, or motility testing.
How many units should be reported?
The code represents sperm-antibody measurement. It is not a per-sperm or per-antibody unit.
Is modifier 26 used for physician interpretation?
Medicare pays 89325 through the CLFS; the physician fee schedule excludes the test by statute, so there is no separate physician-fee-schedule interpretation payment.
How does Medicare pay for 89325?
Medicare uses one national CLFS amount across states and localities, without geographic or office/facility adjustment.
Where this amount comes from
FeeBase reads lab amounts directly from the CMS Clinical Laboratory Fee Schedule file for the quarter: one row per code, with its payment indicator and national amount. Contractor-priced tests are labeled, never given a made-up amount. Amounts are Medicare payment limits, not a patient’s bill or a commercial rate.
CMS CLFS 2026 Q4 · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file line behind this amount
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