HCPCS code J9355: Trastuzumab injection, per 10 mg, non-biosimilar2026 Medicare rate & RVUs in Michigan

Reports non-biosimilar trastuzumab given by injection, commonly in oncology treatment for HER2-positive breast or gastric cancer, in 10 mg units.

CMS RVU26DEffective Oct 1, 20262 payment localities

CMS doesn’t publish an office rate for J9355 in Michigan.

—Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Michigan
  2. What J9355 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What J9355 covers

J9355 represents non-biosimilar trastuzumab, an intravenous monoclonal antibody used in treatment regimens for HER2-positive breast cancer and certain HER2-positive gastric or gastroesophageal junction cancers. Oncology practices and hospital outpatient departments commonly report the drug when it is administered as part of a treatment course. This code is for trastuzumab itself, not an antibody-drug conjugate or a subcutaneous trastuzumab combination.

CMS assigns status E, which excludes the drug from the physician fee schedule; when Medicare covers it, payment is made under another method. The HCPCS pricing method identifies it as a Part B drug generally paid using CMS quarterly ASP drug pricing files when covered. The Medicare contractor determines coverage. Each billing unit represents 10 mg of trastuzumab, so the administered dose is converted into 10 mg units. The drug code represents the medication, while a reportable infusion administration is a separate service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where J9355 pays more and less in Michigan

J9355 office and facility rates by payment locality
Payment localityOfficeFacility
Detroit, MIUnavailableUnavailable
Rest of MichiganUnavailableUnavailable

How the J9355 rate is calculated

Each of J9355’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · J9355

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for J9355

J9355 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · J9355

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

J9355 isn’t priced in this setting.

J9355 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • J9355

    Trastuzumab injection, per 10 mg, non-biosimilar0 wRVU

    Not priced

  • J9354

    Ado-trastuzumab emtansine, per 1 mg0 wRVU

    Not priced

  • J9356

    Trastuzumab combination, per 10 mg trastuzumab0 wRVU

    Not priced

  • J9358

    Fam-trastuzumab deruxtecan, per 1 mg0 wRVU

    Not priced

  • Q5117

    Kanjinti injection, per 10 mg0 wRVU

    Not priced

How to choose

J9354Ado-trastuzumab emtansinePer 1 mg
J9354 is ado-trastuzumab emtansine, an antibody-drug conjugate. J9355 is non-biosimilar trastuzumab without that attached drug.
J9356Trastuzumab combinationPer 10 mg trastuzumab
J9356 is the subcutaneous trastuzumab and hyaluronidase product; J9355 represents intravenous trastuzumab.
J9358Fam-trastuzumab deruxtecanPer 1 mg
J9358 represents trastuzumab deruxtecan, a distinct antibody-drug conjugate, not trastuzumab alone.
Q5117Kanjinti injectionPer 10 mg
Q5117 identifies trastuzumab-anns, a biosimilar. J9355 is for trastuzumab excluding biosimilars.

J9355 billing questions

How many units should be reported?

Each unit represents 10 mg of trastuzumab. Divide the administered dose in milligrams by 10 to determine the number of units.

Does J9355 include trastuzumab biosimilars?

No. J9355 is for trastuzumab excluding biosimilars; use the applicable HCPCS code for the specific biosimilar administered.

How is J9355 different from J9356?

J9355 represents intravenous trastuzumab. J9356 represents a subcutaneous trastuzumab and hyaluronidase product.

Is the infusion administration included in J9355?

J9355 represents the drug. Report a separately identifiable, reportable infusion administration service separately.

How does Medicare treat this code?

CMS excludes J9355 from the physician fee schedule under status E. When covered, it is a Part B drug generally priced using CMS quarterly ASP drug pricing files, and the Medicare contractor determines coverage.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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