HCPCS code Q4108: Wound matrix, integra Matrix2026 Medicare rate & RVUs in Massachusetts
Report Integra Matrix for the wound-matrix product used with a primary wound procedure, with units reflecting the product area represented by the code.
Medicare pays $134.00–$151.95 for Q4108 in the office in Massachusetts, from Rest of Massachusetts to Metropolitan Boston, MA. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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What Q4108 covers
Q4108 identifies Integra Matrix, a wound-care matrix product used on a prepared wound bed. It may be encountered in wound-care services and surgical treatment of wounds; wound-care clinicians and surgeons typically document the wound treated and the product used. It is distinct from other Integra products, including bilayer matrix wound dressing, dermal regeneration template, and flowable wound matrix.
CMS classifies Q4108 as an add-on code, so report it only with a primary procedure; its payment falls within that procedure’s global period. The code is technical-component-only, with interpretation covered by a separate code. Documentation should identify Integra Matrix, the treated wound site, the primary procedure, and the quantity applied. Use the product’s square-centimeter unit when reporting the quantity, and ensure the primary procedure matches the service performed and wound location.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4108 pays more and less in Massachusetts
| Payment locality | Office | Facility |
|---|---|---|
| Metropolitan Boston, MA | $151.95 | Unavailable |
| Rest of Massachusetts | $134.00 | Unavailable |
How the Q4108 rate is calculated
Each of Q4108’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4108
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4108
The CMS indicators that decide how Q4108 is paid alongside other services.
CMS payment indicators · Q4108
Wound matrix, integra Matrix
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4108 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- Q4104Wound matrixIntegra BMWD
- Q4104 is for Integra Bilayer Matrix Wound Dressing. Use Q4108 for Integra Matrix, based on the product documented and supplied.
- Q4105Skin substituteIntegra DRT or Omnigraft
- Q4105 identifies Integra Dermal Regeneration Template or Omnigraft. It is not interchangeable with the Integra Matrix product reported under Q4108.
- Q4114Integra flowable matrixPer 1 cc
- Q4114 identifies Integra Flowable Wound Matrix. Select it for that flowable product, not for Integra Matrix reported under Q4108.
Q4108 billing questions
How is Q4108 different from Q4104 or Q4105?
Q4108 identifies Integra Matrix. Q4104 identifies Integra Bilayer Matrix Wound Dressing, while Q4105 identifies Integra Dermal Regeneration Template or Omnigraft; report the product actually used.
Can Q4108 be billed by itself?
No. CMS identifies it as an add-on code, so it must be reported with a primary procedure and is paid within that procedure’s global period.
What should the record support?
Document the Integra Matrix product, wound site, primary procedure, and quantity applied. The reported units should reflect the product quantity represented in square centimeters.
Does Q4108 include interpretation?
CMS classifies Q4108 as technical-component-only; a separate code covers interpretation. The record and claim should distinguish the technical service from any separately coded interpretation.
Which application procedure may be reported with Q4108?
A skin-substitute application procedure may serve as the primary procedure, with the specific code selected according to the treated site and service. Q4108 is not reported without that primary procedure.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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