HCPCS code Q4220: Skin substitute, bellacell HD or SureDerm2026 Medicare rate & RVUs in Massachusetts

Reports the square-centimeter supply of Bellacell HD or SureDerm used with a skin-substitute application procedure for wound treatment.

CMS RVU26DEffective Oct 1, 20262 payment localities

Medicare pays $134.00–$151.95 for Q4220 in the office in Massachusetts, from Rest of Massachusetts to Metropolitan Boston, MA. Which amount applies depends on the service address.

$134.00–$151.95Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Massachusetts
  2. What Q4220 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4220 covers

Q4220 represents the supplied Bellacell HD or SureDerm product, rather than the clinician’s work applying it. These products may be used in wound care, including in outpatient wound clinics and surgical or podiatric practices. The clinician separately performs and reports the appropriate application procedure; the product code identifies the specific material supplied for that treatment.

Report the product in square-centimeter units based on the amount used, and pair it with a qualifying primary application procedure. Keep documentation that identifies Bellacell HD or SureDerm and supports the quantity supplied and applied. CMS classifies Q4220 as an add-on: it is not billed alone, and payment falls within the primary procedure’s global period. It is a technical-component-only code; a separate applicable code covers interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4220 pays more and less in Massachusetts

Q4220 office and facility rates by payment locality
Payment localityOfficeFacility
Metropolitan Boston, MA$151.95Unavailable
Rest of Massachusetts$134.00Unavailable

How the Q4220 rate is calculated

Each of Q4220’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4220

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4220

The CMS indicators that decide how Q4220 is paid alongside other services.

CMS payment indicators · Q4220

Skin substitute, bellacell HD or SureDerm

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4220 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q4220

    Skin substitute, bellacell HD or SureDerm0 wRVU

    $127.26

  • 15271

    Skin substitute graft, first 25 cm², trunk/limbs1.46 wRVU

    $157.99+$30.73

  • 15275

    Skin substitute, face and other specified sites1.78 wRVU

    $160.32+$33.06

  • Q4221

    Wound product, amnioWrap2, per square centimeter0 wRVU

    $127.26+$0.00

How to choose

15271Skin substitute graftFirst 25 cm², trunk/limbs
15271 reports the application service for its applicable site group; Q4220 reports the Bellacell HD or SureDerm product supplied for that service.
15275Skin substituteFace and other specified sites
15275 reports application at its applicable face, scalp, hand, foot, or genital site group. Q4220 identifies the product, not the application work.
Q4221Wound productAmnioWrap2, per square centimeter
Q4221 identifies Amniowrap2, while Q4220 identifies Bellacell HD or SureDerm. Choose by the product documented as supplied, not by wound dimensions alone.

Q4220 billing questions

Can Q4220 be billed by itself?

No. CMS identifies it as an add-on, so report it with the primary wound application procedure.

How should units be determined?

Use square-centimeter units for the Bellacell HD or SureDerm product supplied and applied. The record should support the product identity and quantity.

Is the application procedure included in Q4220?

No. Q4220 identifies the product; report the appropriate application procedure separately as the primary service.

Does Q4220 include a professional interpretation component?

No. CMS classifies Q4220 as technical-component-only, with interpretation covered by a separate applicable code.

Should Q4220 be reported instead of Q4221?

Select the HCPCS code that matches the product actually supplied. Q4221 identifies a different product, Amniowrap2, and is not selected based only on wound size.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4220PPRRVU2026_Oct_nonQPP.csv, line 18,311 (RVU26D)

Open CMS sourceHow we calculate rates

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