HCPCS code Q4224: Wound matrix, HHF10-P per square centimeter2026 Medicare rate & RVUs in Missouri
Q4224 represents HHF10-P by square-centimeter quantity when the product is used with a primary wound-treatment procedure.
Medicare pays $109.70–$121.15 for Q4224 in the office in Missouri, from Rest of Missouri to Metropolitan St. Louis, MO. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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What Q4224 covers
Q4224 identifies HHF10-P, a wound-care tissue product reported by square-centimeter quantity. It represents the product used during wound treatment, rather than the clinician’s work to prepare or apply it. Wound-care clinicians and surgeons may use the product in outpatient or facility settings when treating a wound and performing a separately coded primary procedure.
Report Q4224 with the applicable primary procedure, not by itself; CMS treats it as an add-on code paid within that procedure’s global period. Record the product and the square-centimeter quantity used, along with the wound site and the associated procedure. CMS classifies Q4224 as technical-component-only, with interpretation covered by a separate code. The primary procedure code describes the wound treatment; Q4224 identifies the HHF10-P product quantity.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4224 pays more and less in Missouri
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
3 payment localities
$109.70 to $121.15
| Payment locality | Office | Facility |
|---|---|---|
| Metropolitan Kansas City, MO | $119.49 | Unavailable |
| Metropolitan St. Louis, MO | $121.15 | Unavailable |
| Rest of Missouri | $109.70 | Unavailable |
How the Q4224 rate is calculated
Each of Q4224’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4224
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4224
The CMS indicators that decide how Q4224 is paid alongside other services.
CMS payment indicators · Q4224
Wound matrix, HHF10-P per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4224 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- Q4223Ocular membrane productDermabind SL Optic, per cm²
- Q4223 identifies a different wound-care product. Use Q4224 for HHF10-P and select Q4223 only when that code’s product was used.
- Q4225Skin substituteAmnio or DermaTL
- Q4225 identifies a different product, despite also being reported by square-centimeter quantity. The product used determines which HCPCS code applies.
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- CPT 15271 reports a skin substitute application service at a qualifying site; Q4224 reports the HHF10-P product quantity and is billed with a primary procedure.
Q4224 billing questions
Can Q4224 be reported by itself?
No. CMS identifies Q4224 as an add-on code that must be billed with a primary procedure.
Which service is commonly paired with Q4224?
Pair it with the applicable skin substitute application procedure, such as CPT 15271 for a qualifying trunk, arm, or leg site.
How should the quantity be documented?
Document the HHF10-P product and the square-centimeter quantity used, along with the treated wound site and the primary procedure.
Does Q4224 include the wound application work?
No. Q4224 identifies the product quantity; report the appropriate primary procedure for the wound-treatment service.
Is there a separate interpretation component?
CMS classifies Q4224 as technical-component-only and states that a separate code covers interpretation.
How does Q4224 differ from Q4223?
Both are product-specific codes reported by square-centimeter quantity, but Q4224 identifies HHF10-P and Q4223 identifies a different product. Select the code matching the product used.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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