HCPCS code Q4229: Amniotic membrane, cogenex, per square centimeter2026 Medicare rate & RVUs in Maryland
Reports Cogenex amniotic membrane furnished for wound coverage, measured by the square centimeter and paired with the applicable skin-substitute application procedure.
Medicare pays $128.78–$149.91 for Q4229 in the office in Maryland, from Rest of Maryland to Washington, DC area. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What Q4229 covers
Q4229 identifies Cogenex amniotic membrane supplied for wound coverage, with the product quantity measured in square centimeters. It represents the product rather than the clinician’s wound preparation or application work. It may be used in wound-care settings where a clinician applies the membrane as part of treatment; the application procedure is reported separately. The code is specific to this Cogenex membrane and should not be substituted for another product code based only on the products’ shared amniotic origin.
Report Q4229 with the primary skin-substitute application procedure appropriate to the wound’s site and treated area, using documentation of the product and square centimeters furnished. CMS classifies it as an add-on code, so it is billed only with a primary procedure and paid within that procedure’s global period. Its valuation reflects practice expense, with no physician work or malpractice RVUs. It is technical-component-only; a separate code covers interpretation.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4229 pays more and less in Maryland
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
3 payment localities
$128.78 to $149.91
| Payment locality | Office | Facility |
|---|---|---|
| Baltimore area, MD | $136.55 | Unavailable |
| Rest of Maryland | $128.78 | Unavailable |
| Washington, DC area | $149.91 | Unavailable |
How the Q4229 rate is calculated
Each of Q4229’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4229
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4229
The CMS indicators that decide how Q4229 is paid alongside other services.
CMS payment indicators · Q4229
Amniotic membrane, cogenex, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4229 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- Q4230Cogenex flowable amnionPer 0.5 cc
- Q4230 identifies Cogenex Flow amnion and is measured per 0.5 cc; Q4229 identifies Cogenex amniotic membrane and is measured per square centimeter. Report the code for the product actually furnished.
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- 15271 reports the application procedure for qualifying wounds on the trunk, arms, or legs; Q4229 reports the Cogenex membrane product used with an application procedure.
- 15275Skin substituteFace and other specified sites
- 15275 reports the application procedure for qualifying wounds at specified anatomical sites, including the head, face, neck, hands, feet, or genitalia. Q4229 reports the product, not the application.
Q4229 billing questions
Can Q4229 be billed by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure. Pair it with the applicable skin-substitute application procedure.
How are units reported?
The code is measured per square centimeter. Document the product quantity furnished and the wound site and treated area supporting the reported units.
Is the application work included in Q4229?
No. Q4229 identifies the Cogenex membrane product; report the appropriate application procedure separately. CMS pays Q4229 within that primary procedure’s global period.
How does Q4229 differ from Q4230?
Q4229 identifies Cogenex amniotic membrane measured by square centimeter. Q4230 identifies Cogenex Flow amnion measured by 0.5 cc, so select the code matching the product furnished.
Does Q4229 include interpretation?
No. CMS classifies Q4229 as technical-component-only and assigns interpretation to a separate code.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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