HCPCS code Q4321: Renograft graft, per square centimeter2026 Medicare rate & RVUs in Maine
Q4321 reports Renograft by square centimeter when furnished with a primary wound procedure involving graft application.
Medicare pays $117.08–$126.11 for Q4321 in the office in Maine, from Rest of Maine to Southern Maine, ME. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What Q4321 covers
Q4321 identifies Renograft supplied by the square centimeter for use with a wound procedure. The product line is reported alongside the primary procedure that applies the graft; it is not a standalone service. The code is relevant to wound care encounters in which the documented product used is Renograft.
Report the quantity in square centimeters and retain documentation supporting the product used and the quantity furnished. CMS classifies Q4321 as an add-on code, so it must accompany a primary procedure and its payment is within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation. The application procedure is selected separately according to the service performed and applicable site and area criteria.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4321 pays more and less in Maine
| Payment locality | Office | Facility |
|---|---|---|
| Rest of Maine | $117.08 | Unavailable |
| Southern Maine, ME | $126.11 | Unavailable |
How the Q4321 rate is calculated
Each of Q4321’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4321
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4321
The CMS indicators that decide how Q4321 is paid alongside other services.
CMS payment indicators · Q4321
Renograft graft, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4321 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- This is an application procedure, not the Renograft product code. It applies to qualifying trunk, arm, or leg sites; Q4321 identifies the product furnished.
- 15275Skin substituteFace and other specified sites
- This is an application procedure for qualifying head, neck, hand, foot, or genital sites. Q4321 reports Renograft rather than the application service.
- Q4320Wound graftPellograft, per square centimeter
- Q4320 identifies Pellograft, while Q4321 identifies Renograft. Select the product code matching the material actually furnished.
Q4321 billing questions
Can Q4321 be reported by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure.
How is the Q4321 quantity reported?
The descriptor is per square centimeter. Document the Renograft quantity furnished in square centimeters.
Does Q4321 include interpretation?
No. CMS classifies Q4321 as technical-component-only; a separate code covers interpretation.
Which application code is paired with Q4321?
Pair it with the primary procedure that applies the graft. For example, the applicable wound-graft application code depends on the treated site and area.
What documentation supports Q4321?
Document that Renograft was used and the quantity furnished in square centimeters, along with the primary wound procedure.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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