HCPCS code Q4327: Amniotic allograft, duoamnion, per square centimeter2026 Medicare rate & RVUs in California
Reports Duoamnion amniotic membrane allograft supplied for wound application, with units representing the square centimeters furnished alongside a primary procedure.
Medicare pays $139.47–$183.51 for Q4327 in the office in California, from Bakersfield, CA to Santa Clara County, CA. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What Q4327 covers
Q4327 identifies Duoamnion, a named amniotic membrane allograft supplied for application to a wound. Wound-care clinicians, including physicians and podiatrists, may use it as a covering on a prepared wound bed during outpatient wound treatment. The product line is distinct from the procedure used to prepare and apply the graft; wound debridement or other wound management may occur in the same encounter when separately supported.
Report Q4327 only with a primary procedure, commonly an appropriate skin-substitute application code from the 15271–15278 family, selected for the treated site and wound area. The product record and clinical documentation should identify Duoamnion, the wound treated, and the square centimeters furnished. CMS classifies Q4327 as an add-on code paid within the primary procedure’s global period, so it is not a stand-alone service. CMS also classifies it as technical-component-only; interpretation is represented by a separate code.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4327 pays more and less in California
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
29 payment localities
$139.47 to $183.51
29 of 29 payment localities
| Payment locality | Office | Facility |
|---|---|---|
| Bakersfield, CA | $139.47 | Unavailable |
| Chico, CA | $139.47 | Unavailable |
| El Centro, CA | $139.47 | Unavailable |
| Fresno, CA | $139.47 | Unavailable |
| Hanford, CA | $139.47 | Unavailable |
| Los Angeles, CA | $150.55 | Unavailable |
| Madera, CA | $139.47 | Unavailable |
| Marin County, CA | $179.43 | Unavailable |
| Merced, CA | $139.47 | Unavailable |
| Modesto, CA | $139.47 | Unavailable |
| Napa, CA | $167.73 | Unavailable |
| Oxnard, CA | $150.42 | Unavailable |
| Redding, CA | $139.47 | Unavailable |
| Rest of California | $139.47 | Unavailable |
| Riverside, CA | $139.47 | Unavailable |
| Sacramento, CA | $148.00 | Unavailable |
| Salinas, CA | $147.49 | Unavailable |
| San Benito County, CA | $183.51 | Unavailable |
| San Diego, CA | $152.20 | Unavailable |
| San Francisco, CA | $179.43 | Unavailable |
| San Luis Obispo, CA | $144.95 | Unavailable |
| Santa Clara County, CA | $183.51 | Unavailable |
| Santa Cruz, CA | $154.62 | Unavailable |
| Santa Maria, CA | $148.38 | Unavailable |
| Santa Rosa, CA | $156.27 | Unavailable |
| Stockton, CA | $139.47 | Unavailable |
| Vallejo, CA | $167.73 | Unavailable |
| Visalia, CA | $139.47 | Unavailable |
| Yuba City, CA | $139.47 | Unavailable |
How the Q4327 rate is calculated
Each of Q4327’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4327
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4327
The CMS indicators that decide how Q4327 is paid alongside other services.
CMS payment indicators · Q4327
Amniotic allograft, duoamnion, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4327 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- Q4328Wound productMost, per square centimeter
- Q4328 identifies Most, while Q4327 identifies Duoamnion. The product documentation determines which code to report.
- Q4329Wound graftSinglay, per square centimeter
- Q4329 identifies Singlay, not Duoamnion. Do not select between them based only on the shared per-square-centimeter unit.
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- 15271 reports a primary skin-substitute application procedure; Q4327 reports the Duoamnion product as an add-on. The appropriate application code depends on the wound site and area.
Q4327 billing questions
What distinguishes Q4327 from another per-square-centimeter graft code?
Q4327 identifies Duoamnion specifically. Select the code that matches the product record rather than choosing among graft codes by unit of measure alone.
Can Q4327 be billed by itself?
No. CMS identifies it as an add-on code that must be reported with a primary procedure; an appropriate skin-substitute application procedure is a common pairing.
How should units be determined?
The code is measured per square centimeter. The product and wound documentation should support the square centimeters reported.
Does Q4327 include interpretation?
No. CMS classifies Q4327 as technical-component-only and indicates that a separate code covers interpretation.
What documentation supports reporting Q4327?
Document the Duoamnion product used, the wound treated, the application procedure, and the square centimeters furnished.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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