HCPCS code Q4330: Wound graft, total, per square centimeter2026 Medicare rate & RVUs in Guam

Reports Total wound graft material by square centimeter when supplied for application to a wound during a primary wound procedure.

CMS RVU26DEffective Oct 1, 20261 payment locality

Medicare pays $144.69 for Q4330 in the office in Guam (Hawaii, Guam, HI). Which amount applies depends on the service address.

$144.69Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in Guam
  2. What Q4330 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4330 covers

Q4330 identifies Total, a wound graft or skin-substitute product, measured per square centimeter. A wound-care clinician, podiatrist, surgeon, or other treating practitioner may use the material on a wound bed as part of wound treatment. The product code identifies the material; it does not describe the clinical work of preparing the wound or applying the graft.

Report the number of square centimeters supported by the record, along with the primary procedure for the wound application. Documentation should identify Total as the product used and support the amount applied, such as through the treated wound’s dimensions and the amount of material used. CMS designates Q4330 as an add-on code: it must be billed with a primary procedure, and payment falls within that procedure’s global period. CMS also classifies it as technical-component-only; interpretation is represented by a separate code, not Q4330.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Q4330 in Hawaii, Guam, HI

Q4330 office and facility rates by payment locality
Payment localityOfficeFacility
Hawaii, Guam, HI$144.69Unavailable

How the Q4330 rate is calculated

Each of Q4330’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4330

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4330

The CMS indicators that decide how Q4330 is paid alongside other services.

CMS payment indicators · Q4330

Wound graft, total, per square centimeter

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4330 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q4330

    Wound graft, total, per square centimeter0 wRVU

    $127.26

  • Q4329

    Wound graft, singlay, per square centimeter0 wRVU

    $127.26+$0.00

  • Q4331

    Wound matrix, axolotl, per square centimeter0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft, first 25 cm², trunk/limbs1.46 wRVU

    $157.99+$30.73

How to choose

Q4329Wound graftSinglay, per square centimeter
Q4329 identifies Singlay, while Q4330 identifies Total. Match the reported product to the product documented as used.
Q4331Wound matrixAxolotl, per square centimeter
Q4331 identifies Axolotl graft rather than Total. These product-specific codes are not interchangeable based only on the wound site.
15271Skin substitute graftFirst 25 cm², trunk/limbs
15271 reports the application service for qualifying trunk, arm, or leg wounds; Q4330 identifies the Total material supplied for that service.

Q4330 billing questions

What primary service should accompany Q4330?

Report Q4330 with the primary procedure for applying the wound graft material, such as an appropriate skin-substitute application service. Q4330 identifies the Total product, not the application work.

How should the quantity be determined?

The code is measured per square centimeter. Record the amount of Total used and the treated wound area so the reported quantity is supported.

How is Q4330 different from Q4331?

Q4330 identifies Total; Q4331 identifies Axolotl graft. Select the code matching the product actually used and documented.

Is interpretation included in Q4330?

No. CMS classifies Q4330 as technical-component-only and indicates that a separate code covers interpretation.

Does Q4330 have a separate global period?

No separate period is described for Q4330. CMS treats it as an add-on paid within the primary procedure’s global period.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4330PPRRVU2026_Oct_nonQPP.csv, line 18,417 (RVU26D)
Geographic factors for Hawaii, Guam, HIGPCI2026.csv, line 46 (RVU26D)

Open CMS sourceHow we calculate rates

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