HCPCS code Q4378: Wound matrix, renew FT, per square centimeter2026 Medicare rate & RVUs in Texas
Reports each square centimeter of Renew FT Matrix supplied with a primary wound procedure that applies a matrix to a treated wound bed.
Medicare pays $115.80–$134.64 for Q4378 in the office in Texas, from Beaumont, TX to Austin, TX. Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 9 sections
What Q4378 covers
Q4378 identifies the Renew FT Matrix product used in wound care. A clinician applies the matrix to a prepared wound bed as part of treatment; the product line represents the material, not the work of preparing the site or applying it. It is reported by the area of product supplied, rather than by the number of wounds or applications. The related application service is generally reported separately.
Report the product only with a primary procedure, using documentation that identifies Renew FT Matrix and supports the square-centimeter quantity supplied. CMS treats Q4378 as an add-on, paid within the primary procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation. The product code does not replace the application procedure code, and its units should reflect the area documented for the product used.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4378 pays more and less in Texas
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
8 payment localities
$115.80 to $134.64
8 of 8 payment localities
| Payment locality | Office | Facility |
|---|---|---|
| Austin, TX | $134.64 | Unavailable |
| Beaumont, TX | $115.80 | Unavailable |
| Brazoria, TX | $126.11 | Unavailable |
| Dallas, TX | $126.75 | Unavailable |
| Fort Worth, TX | $125.48 | Unavailable |
| Galveston, TX | $126.37 | Unavailable |
| Houston, TX | $126.37 | Unavailable |
| Rest of Texas | $120.77 | Unavailable |
How the Q4378 rate is calculated
Each of Q4378’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4378
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4378
The CMS indicators that decide how Q4378 is paid alongside other services.
CMS payment indicators · Q4378
Wound matrix, renew FT, per square centimeter
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4378 compared with similar codes
Compare codes · National
5 codes, side by side
How to choose
- 15271Skin substitute graftFirst 25 cm², trunk/limbs
- This is an application procedure for qualifying trunk or extremity sites; Q4378 reports Renew FT Matrix supplied with the primary procedure.
- 15275Skin substituteFace and other specified sites
- This application procedure covers qualifying head, neck, hand, foot, or genital sites. Q4378 identifies the product, not the application or anatomical site.
- Q4377Skin substituteTrigraft, per sq cm
- Q4377 identifies Trigraft FT, whereas Q4378 identifies Renew FT Matrix. Report the product actually supplied.
- Q4379Wound graftAmnioDefend FT, per sq cm
- Q4379 identifies Amniodefend FT, not Renew FT Matrix. The product-specific code follows the material used.
Q4378 billing questions
Is Q4378 the wound application procedure?
No. It identifies the Renew FT Matrix product by square centimeter. Report the wound application procedure separately when performed.
What should support the units?
Document the product used and the square-centimeter area supplied. Do not base units on the number of wounds alone.
Can Q4378 be reported by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure.
How does the global-period rule affect this code?
Payment for Q4378 is within the primary procedure’s global period. It is not separately paid outside that procedure’s global period.
Is there a separate professional interpretation component?
CMS classifies Q4378 as technical-component-only, with interpretation covered by a separate code.
How is Q4378 different from Q4377 or Q4379?
Those codes identify Trigraft FT and Amniodefend FT, respectively. Select the code matching the product actually supplied; their product quantities are not interchangeable.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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