HCPCS code Q5126: Alymsys injection, per 10 mg2026 Medicare rate & RVUs in California

Reports Alymsys, a bevacizumab biosimilar given intravenously in oncology treatment when the administered dose is billed by 10 mg.

CMS RVU26DEffective Oct 1, 202629 payment localities

CMS doesn’t publish an office rate for Q5126 in California.

—Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 9 sections
  1. Rate in California
  2. What Q5126 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q5126 covers

Alymsys is a bevacizumab biosimilar used intravenously in oncology regimens for selected cancers, including colorectal, non-squamous lung, renal, cervical, and ovarian cancers. Oncology practices, infusion centers, and hospital outpatient departments may report this drug code when Alymsys is administered. The code identifies the specific product, not bevacizumab products generally; use it when Alymsys was the product supplied.

CMS assigns this code physician fee schedule status E, meaning it is excluded from the physician fee schedule. When Medicare covers the drug, it is treated as a Part B drug and generally priced through CMS’s quarterly Average Sales Price drug pricing files; coverage is left to the Medicare contractor’s judgment. Each billing unit represents 10 mg of bevacizumab-maly. Report the administered dose in 10 mg units, and report the infusion administration service separately when furnished and supported by the claim.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q5126 pays more and less in California

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

29 of 29 payment localities

Q5126 office and facility rates by payment locality
Payment localityOfficeFacility
Bakersfield, CAUnavailableUnavailable
Chico, CAUnavailableUnavailable
El Centro, CAUnavailableUnavailable
Fresno, CAUnavailableUnavailable
Hanford, CAUnavailableUnavailable
Los Angeles, CAUnavailableUnavailable
Madera, CAUnavailableUnavailable
Marin County, CAUnavailableUnavailable
Merced, CAUnavailableUnavailable
Modesto, CAUnavailableUnavailable

How the Q5126 rate is calculated

Each of Q5126’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q5126

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q5126

Q5126 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · Q5126

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

Q5126 isn’t priced in this setting.

Q5126 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q5126

    Alymsys injection, per 10 mg0 wRVU

    Not priced

  • Q5118

    Zirabev injection, per 10 mg0 wRVU

    Not priced

  • Q5129

    Vegzelma injection, per 10 mg0 wRVU

    Not priced

  • J9035

    Bevacizumab, per 10 mg0 wRVU

    Not priced

How to choose

Q5118Zirabev injectionPer 10 mg
Q5118 identifies Zirabev (bevacizumab-bvzr); Q5126 identifies Alymsys (bevacizumab-maly). Select the code for the product administered.
Q5129Vegzelma injectionPer 10 mg
Q5129 identifies Vegzelma (bevacizumab-adcd); Q5126 identifies Alymsys. These are distinct bevacizumab biosimilar products.
J9035BevacizumabPer 10 mg
J9035 identifies bevacizumab, while Q5126 is specific to the Alymsys biosimilar. Use the product-specific code matching the drug supplied.

Q5126 billing questions

When should a practice use Q5126 instead of another bevacizumab code?

Use Q5126 when the administered product was Alymsys (bevacizumab-maly). Other bevacizumab products have their own HCPCS codes.

How many milligrams does one unit represent?

One unit represents 10 mg of bevacizumab-maly. Calculate units from the administered dose in 10 mg increments.

Does Q5126 include the infusion administration?

No. Q5126 identifies the drug; report the infusion administration service separately when it was furnished and is supported by the claim.

How does Medicare treat Q5126?

CMS assigns status E, excluding it from the physician fee schedule. When covered, it is a Part B drug generally priced using CMS’s quarterly ASP drug pricing files, and coverage is left to the Medicare contractor’s judgment.

What should the medical record support?

Document that Alymsys was administered and record the dose given. The product and dose documentation should support the reported units.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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